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7NNL
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BU of 7nnl by Molmil
Cryo-EM structure of the KdpFABC complex in an E1-ATP conformation loaded with K+
Descriptor: CARDIOLIPIN, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, POTASSIUM ION, ...
Authors:Silberberg, J.M, Corey, R.A, Hielkema, L, Stock, C, Stansfeld, P.J, Paulino, C, Haenelt, I.
Deposit date:2021-02-25
Release date:2021-07-28
Last modified:2021-09-29
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Deciphering ion transport and ATPase coupling in the intersubunit tunnel of KdpFABC.
Nat Commun, 12, 2021
7N73
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BU of 7n73 by Molmil
Cryo-EM structure of ATP13A2 in the ADP-AlF-bound E1P-ADP-like state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, CHOLESTEROL HEMISUCCINATE, Isoform 3 of Polyamine-transporting ATPase 13A2, ...
Authors:Sim, S.I, Park, E.
Deposit date:2021-06-09
Release date:2021-11-10
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural basis of polyamine transport by human ATP13A2 (PARK9).
Mol.Cell, 81, 2021
7N72
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BU of 7n72 by Molmil
Cryo-EM structure of ATP13A2 in the AlF-bound E2-Pi-like state
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CHOLESTEROL HEMISUCCINATE, DODECYL-BETA-D-MALTOSIDE, ...
Authors:Sim, S.I, Park, E.
Deposit date:2021-06-09
Release date:2021-11-10
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Structural basis of polyamine transport by human ATP13A2 (PARK9).
Mol.Cell, 81, 2021
7N74
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BU of 7n74 by Molmil
Cryo-EM structure of ATP13A2 D508N mutant in the E1-ATP-like state
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CHOLESTEROL HEMISUCCINATE, Isoform 3 of Polyamine-transporting ATPase 13A2, ...
Authors:Sim, S.I, Park, E.
Deposit date:2021-06-09
Release date:2021-11-10
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structural basis of polyamine transport by human ATP13A2 (PARK9).
Mol.Cell, 81, 2021
7N70
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BU of 7n70 by Molmil
Cryo-EM structure of ATP13A2 in the BeF-bound E2P-like state
Descriptor: BERYLLIUM TRIFLUORIDE ION, CHOLESTEROL HEMISUCCINATE, DODECYL-BETA-D-MALTOSIDE, ...
Authors:Sim, S.I, Park, E.
Deposit date:2021-06-09
Release date:2021-11-10
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structural basis of polyamine transport by human ATP13A2 (PARK9).
Mol.Cell, 81, 2021
7N78
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BU of 7n78 by Molmil
Cryo-EM structure of ATP13A2 in the E2-Pi state
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CHOLESTEROL HEMISUCCINATE, DODECYL-BETA-D-MALTOSIDE, ...
Authors:Sim, S.I, Park, E.
Deposit date:2021-06-09
Release date:2021-11-10
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural basis of polyamine transport by human ATP13A2 (PARK9).
Mol.Cell, 81, 2021
7N75
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BU of 7n75 by Molmil
Cryo-EM structure of ATP13A2 D458N/D962N mutant in the E1-apo state, Conformation 1
Descriptor: Isoform 3 of Polyamine-transporting ATPase 13A2
Authors:Sim, S.I, Park, E.
Deposit date:2021-06-09
Release date:2021-11-10
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural basis of polyamine transport by human ATP13A2 (PARK9).
Mol.Cell, 81, 2021
7N76
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BU of 7n76 by Molmil
Cryo-EM structure of ATP13A2 D458N/D962N mutant in the E1-apo state, Conformation 2
Descriptor: Isoform 3 of Polyamine-transporting ATPase 13A2
Authors:Sim, S.I, Park, E.
Deposit date:2021-06-09
Release date:2021-11-10
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural basis of polyamine transport by human ATP13A2 (PARK9).
Mol.Cell, 81, 2021
7N77
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BU of 7n77 by Molmil
Cryo-EM structure of ATP13A2 D458N/D962N mutant in the AlF-bound E1P-like state
Descriptor: CHOLESTEROL HEMISUCCINATE, Isoform 3 of Polyamine-transporting ATPase 13A2, MAGNESIUM ION, ...
Authors:Sim, S.I, Park, E.
Deposit date:2021-06-09
Release date:2021-11-10
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural basis of polyamine transport by human ATP13A2 (PARK9).
Mol.Cell, 81, 2021
7NNP
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BU of 7nnp by Molmil
Rb-loaded cryo-EM structure of the E1-ATP KdpFABC complex.
Descriptor: CARDIOLIPIN, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, Potassium-transporting ATPase ATP-binding subunit, ...
Authors:Silberberg, J.M, Corey, R.A, Hielkema, L, Stock, C, Stansfeld, P.J, Paulino, C, Haenelt, I.
Deposit date:2021-02-25
Release date:2021-07-28
Last modified:2021-09-29
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Deciphering ion transport and ATPase coupling in the intersubunit tunnel of KdpFABC.
Nat Commun, 12, 2021
7M5Y
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BU of 7m5y by Molmil
human ATP13A2 in the outward-facing E2 state bound to spermine and magnesium fluoride
Descriptor: (2R)-3-{[(S)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,4,6-trihydroxy-3,5-bis(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dioctanoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ...
Authors:Lee, K.P.K.
Deposit date:2021-03-25
Release date:2022-03-30
Last modified:2022-04-27
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural mechanisms for gating and ion selectivity of the human polyamine transporter ATP13A2.
Mol.Cell, 81, 2021
7M5X
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BU of 7m5x by Molmil
Human ATP13A2 in the outward-facing E2 state bound to spermine and beryllium fluoride
Descriptor: (2R)-3-{[(S)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,4,6-trihydroxy-3,5-bis(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dioctanoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, BERYLLIUM TRIFLUORIDE ION, ...
Authors:Lee, K.P.K.
Deposit date:2021-03-25
Release date:2022-03-30
Last modified:2022-04-27
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Structural mechanisms for gating and ion selectivity of the human polyamine transporter ATP13A2.
Mol.Cell, 81, 2021
7M5V
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BU of 7m5v by Molmil
human ATP13A2 in the AMPPNP-bound occluded state
Descriptor: (2R)-3-{[(S)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,4,6-trihydroxy-3,5-bis(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dioctanoate, 1-DODECANOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Lee, K.P.K.
Deposit date:2021-03-24
Release date:2022-03-30
Last modified:2022-04-27
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural mechanisms for gating and ion selectivity of the human polyamine transporter ATP13A2.
Mol.Cell, 81, 2021
8IOY
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BU of 8ioy by Molmil
Structure of ATP7B C983S/C985S/D1027A mutant with AMP-PNP
Descriptor: Copper-transporting ATPase 2, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Yang, G, Xu, L, Guo, J, Wu, Z.
Deposit date:2023-03-13
Release date:2023-04-26
Last modified:2023-05-03
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structures of the human Wilson disease copper transporter ATP7B.
Cell Rep, 42, 2023
8IJM
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BU of 8ijm by Molmil
Cyo-EM structure of K794A non-gastric proton pump in Na+ bound E1AMPPCP state
Descriptor: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ...
Authors:Abe, K.
Deposit date:2023-02-27
Release date:2023-08-02
Last modified:2023-08-09
Method:ELECTRON MICROSCOPY (3.13 Å)
Cite:An unusual conformation from Na + -sensitive non-gastric proton pump mutants reveals molecular mechanisms of cooperative Na + -binding.
Biochim Biophys Acta Mol Cell Res, 1870, 2023
8IJX
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BU of 8ijx by Molmil
Cryo-EM structure of the gastric proton pump with bound DQ-18
Descriptor: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1-[4-[(5-chloranyl-2-phenylmethoxy-phenyl)methoxy]phenyl]-N-methyl-methanamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Abe, K, Yokoshima, S, Yoshimori, A.
Deposit date:2023-02-28
Release date:2023-08-30
Last modified:2023-10-04
Method:ELECTRON MICROSCOPY (2.08 Å)
Cite:Deep learning driven de novo drug design based on gastric proton pump structures.
Commun Biol, 6, 2023
8IJW
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BU of 8ijw by Molmil
Cryo-EM structure of the gastric proton pump with bound DQ-06
Descriptor: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ...
Authors:Abe, K, Yokoshima, S, Yoshimori, A.
Deposit date:2023-02-28
Release date:2023-08-30
Last modified:2023-10-04
Method:ELECTRON MICROSCOPY (2.19 Å)
Cite:Deep learning driven de novo drug design based on gastric proton pump structures.
Commun Biol, 6, 2023
8IJV
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BU of 8ijv by Molmil
Cryo-EM structure of the gastric proton pump with bound DQ-02
Descriptor: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-[[5-chloranyl-2-(4-chlorophenyl)phenyl]methoxy]-N-methyl-but-2-yn-1-amine, ...
Authors:Abe, K, Yokoshima, S, Yoshimori, A.
Deposit date:2023-02-28
Release date:2023-08-30
Last modified:2023-10-04
Method:ELECTRON MICROSCOPY (2.1 Å)
Cite:Deep learning driven de novo drug design based on gastric proton pump structures.
Commun Biol, 6, 2023
8IJL
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BU of 8ijl by Molmil
Cyo-EM structure of wildtype non-gastric proton pump in the presence of Na+, AlF and ADP
Descriptor: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-{[(4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranosyl)oxy]methyl}-4-{[(3beta,9beta,14beta,17beta,25R)-spirost-5-en-3-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranoside, ...
Authors:Abe, K.
Deposit date:2023-02-27
Release date:2023-10-18
Method:ELECTRON MICROSCOPY (2.62 Å)
Cite:An unusual conformation from Na + -sensitive non-gastric proton pump mutants reveals molecular mechanisms of cooperative Na + -binding.
Biochim Biophys Acta Mol Cell Res, 1870, 2023
8IES
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BU of 8ies by Molmil
Cryo-EM structure of ATP13A2 in the E1P-ADP state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Polyamine-transporting ATPase 13A2, ...
Authors:Liu, Z.M, Mu, J.Q, Xue, C.Y.
Deposit date:2023-02-15
Release date:2023-12-20
Method:ELECTRON MICROSCOPY (3.73 Å)
Cite:Conformational cycle of human polyamine transporter ATP13A2.
Nat Commun, 14, 2023
8IEM
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BU of 8iem by Molmil
Cryo-EM structure of ATP13A2 in the E2P state
Descriptor: BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, Polyamine-transporting ATPase 13A2, ...
Authors:Liu, Z.M, Mu, J.Q, Xue, C.Y.
Deposit date:2023-02-15
Release date:2023-12-20
Method:ELECTRON MICROSCOPY (3.35 Å)
Cite:Conformational cycle of human polyamine transporter ATP13A2.
Nat Commun, 14, 2023
8IEN
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BU of 8ien by Molmil
Cryo-EM structure of ATP13A2 in the E2-Pi state
Descriptor: MAGNESIUM ION, Polyamine-transporting ATPase 13A2, SPERMINE, ...
Authors:Liu, Z.M, Mu, J.Q, Xue, C.Y.
Deposit date:2023-02-15
Release date:2023-12-20
Method:ELECTRON MICROSCOPY (3.25 Å)
Cite:Conformational cycle of human polyamine transporter ATP13A2.
Nat Commun, 14, 2023
8IER
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BU of 8ier by Molmil
Cryo-EM structure of ATP13A2 in the putative of E2 state
Descriptor: Polyamine-transporting ATPase 13A2, SPERMINE
Authors:Liu, Z.M, Mu, J.Q, Xue, C.Y.
Deposit date:2023-02-15
Release date:2023-12-20
Method:ELECTRON MICROSCOPY (4.87 Å)
Cite:Conformational cycle of human polyamine transporter ATP13A2.
Nat Commun, 14, 2023
8IEO
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BU of 8ieo by Molmil
Cryo-EM structure of ATP13A2 in the nominal E1P state
Descriptor: MAGNESIUM ION, Polyamine-transporting ATPase 13A2, SPERMINE, ...
Authors:Liu, Z.M, Mu, J.Q, Xue, C.Y.
Deposit date:2023-02-15
Release date:2023-12-20
Method:ELECTRON MICROSCOPY (3.78 Å)
Cite:Conformational cycle of human polyamine transporter ATP13A2.
Nat Commun, 14, 2023
8IEL
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BU of 8iel by Molmil
Cryo-EM structure of ATP13A2 in the E1-like state
Descriptor: Polyamine-transporting ATPase 13A2
Authors:Liu, Z.M, Mu, J.Q, Xue, C.Y.
Deposit date:2023-02-15
Release date:2023-12-20
Method:ELECTRON MICROSCOPY (5.65 Å)
Cite:Conformational cycle of human polyamine transporter ATP13A2.
Nat Commun, 14, 2023

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數據於2024-06-26公開中

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