5A3Q
Crystal structure of the (SR) Calcium ATPase E2-vanadate complex bound to thapsigargin and TNP-AMPPCP
Summary for 5A3Q
Entry DOI | 10.2210/pdb5a3q/pdb |
Related | 5A3R 5A3S |
Descriptor | SARCOPLASMIC/ENDOPLASMIC RETICULUM CALCIUM ATPASE 1, OCTANOIC ACID [3S-[3ALPHA, 3ABETA, 4ALPHA, 6BETA, 6ABETA, 7BETA, 8ALPHA(Z), 9BALPHA]]-6-(ACETYLOXY)-2,3,-3A,4,5,6,6A,7,8,9B-DECAHYDRO-3,3A-DIHYDROXY-3,6,9-TRIMETHYL-8-[(2-METHYL-1-OXO-2-BUTENYL)OX Y]-2-OXO-4-(1-OXOBUTOXY)-AZULENO[4,5-B]FURAN-7-YL ESTER, oxido(dioxo)vanadium, ... (8 entities in total) |
Functional Keywords | hydrolase, sarco(endo)plasmic reticulum calcium atpase, vanadate, p-type atpase, serca, trinitrophenyl-nucleotide analoges, calcium transport, inhibition, transition state |
Biological source | ORYCTOLAGUS CUNICULUS (RABBIT) |
Total number of polymer chains | 1 |
Total formula weight | 111217.77 |
Authors | Clausen, J.D.,Bublitz, M.,Arnou, B.,Olesen, C.,Andersen, J.P.,Moller, J.V.,Nissen, P. (deposition date: 2015-06-02, release date: 2016-04-13, Last modification date: 2024-01-10) |
Primary citation | Clausen, J.D.,Bublitz, M.,Arnou, B.,Olesen, C.,Andersen, J.P.,Clausen, J.D.,Bublitz, M.,Arnou, B.,Olesen, C.,Andersen, J.P.,Moller, J.V.,Nissen, P. Crystal Structure of the Vanadate-Inhibited Ca(2+)-ATPase. Structure, 24:617-, 2016 Cited by PubMed: 27050689DOI: 10.1016/J.STR.2016.02.018 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.05 Å) |
Structure validation
Download full validation report