5A3Q
Crystal structure of the (SR) Calcium ATPase E2-vanadate complex bound to thapsigargin and TNP-AMPPCP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | SARCOPLASMIC/ENDOPLASMIC RETICULUM CALCIUM ATPASE 1 | polymer | 995 | 109628.6 | 1 | UniProt (P04191) Pfam (PF00690) Pfam (PF00122) Pfam (PF13246) Pfam (PF00702) Pfam (PF00689) | ORYCTOLAGUS CUNICULUS (RABBIT) | SERCA1, SR CA(2+)-ATPASE 1, CALCIUM PUMP 1, CALCIUM-TRANSPORTING ATPASE SARCOPLASMIC RETICULUM TYPE, FAST TWITCH SKELETAL MUSCLE ISOFORM, ENDOPLASMIC RETICULUM CLASS 1/2 CA(2+) ATPASE, SARCOPLASMIC RETICULUM CALCIUM ATPASE 1 |
| 2 | B (A) | OCTANOIC ACID [3S-[3ALPHA, 3ABETA, 4ALPHA, 6BETA, 6ABETA, 7BETA, 8ALPHA(Z), 9BALPHA]]-6-(ACETYLOXY)-2,3,-3A,4,5,6,6A,7,8,9B-DECAHYDRO-3,3A-DIHYDROXY-3,6,9-TRIMETHYL-8-[(2-METHYL-1-OXO-2-BUTENYL)OX Y]-2-OXO-4-(1-OXOBUTOXY)-AZULENO[4,5-B]FURAN-7-YL ESTER | non-polymer | 650.8 | 1 | Chemie (TG1) | |||
| 3 | C (A) | oxido(dioxo)vanadium | non-polymer | 98.9 | 1 | Chemie (VN4) | |||
| 4 | D (A) | Spiro(2,4,6-trinitrobenzene[1,2a]-O2',O3'-methylene-adenosine (beta,gamma-methylene)triphosphate | non-polymer | 716.3 | 1 | Chemie (DL5) | |||
| 5 | E, F (A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 6 | G (A) | POTASSIUM ION | non-polymer | 39.1 | 1 | Chemie (K) | |||
| 7 | H (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 8 | I (A) | water | water | 18.0 | 8 | Chemie (HOH) |
Sequence modifications
A: 1 - 994 (UniProt: P04191)
| PDB | External Database | Details |
|---|---|---|
| Ace 0 | - | acetylation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 109628.6 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1589.2 | |
| All* | Total formula weight | 111217.8 |
