5A3Q
Crystal structure of the (SR) Calcium ATPase E2-vanadate complex bound to thapsigargin and TNP-AMPPCP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | SARCOPLASMIC/ENDOPLASMIC RETICULUM CALCIUM ATPASE 1 | polymer | 995 | 109628.6 | 1 | UniProt (P04191) Pfam (PF00690) Pfam (PF00122) Pfam (PF13246) Pfam (PF08282) Pfam (PF00689) | ORYCTOLAGUS CUNICULUS (RABBIT) | SERCA1, SR CA(2+)-ATPASE 1, CALCIUM PUMP 1, CALCIUM-TRANSPORTING ATPASE SARCOPLASMIC RETICULUM TYPE, FAST TWITCH SKELETAL MUSCLE ISOFORM, ENDOPLASMIC RETICULUM CLASS 1/2 CA(2+) ATPASE, SARCOPLASMIC RETICULUM CALCIUM ATPASE 1 |
| 2 | B (A) | OCTANOIC ACID [3S-[3ALPHA, 3ABETA, 4ALPHA, 6BETA, 6ABETA, 7BETA, 8ALPHA(Z), 9BALPHA]]-6-(ACETYLOXY)-2,3,-3A,4,5,6,6A,7,8,9B-DECAHYDRO-3,3A-DIHYDROXY-3,6,9-TRIMETHYL-8-[(2-METHYL-1-OXO-2-BUTENYL)OX Y]-2-OXO-4-(1-OXOBUTOXY)-AZULENO[4,5-B]FURAN-7-YL ESTER | non-polymer | 650.8 | 1 | Chemie (TG1) PubChem (16759595) PubChem (24867540) PubChem (44120125) PubChem (44400144) PubChem (45934368) PubChem (49827126) PubChem (95223084) PubChem (95223085) PubChem (95223086) PubChem (96327626) PubChem (96327627) PubChem (123922177) PubChem (125038794) PubChem (125038796) PubChem (131676360) PubChem (134692531) PubChem (146586290) PubChem (162925114) PubChem (162925115) PubChem (5428) PubChem (49926) PubChem (73265223) PubChem (95223083) PubChem (6604031) PubChem (125038795) PubChem (125038793) PubChem (126969181) PubChem (129393350) PubChem (155546938) PubChem (446378) PubChem (5321923) PubChem (5353993) PubChem (5458629) PubChem (9830965) | |||
| 3 | C (A) | oxido(dioxo)vanadium | non-polymer | 98.9 | 1 | Chemie (VN4) PubChem (26218) | |||
| 4 | D (A) | Spiro(2,4,6-trinitrobenzene[1,2a]-O2',O3'-methylene-adenosine (beta,gamma-methylene)triphosphate | non-polymer | 715.3 | 1 | Chemie (DL5) PubChem (137349184) | |||
| 5 | E, F (A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) PubChem (888) | |||
| 6 | G (A) | POTASSIUM ION | non-polymer | 39.1 | 1 | Chemie (K) PubChem (813) | |||
| 7 | H (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) PubChem (312) | |||
| 8 | I (A) | water | water | 18.0 | 8 | Chemie (HOH) |
Sequence modifications
A: 1 - 994 (UniProt: P04191)
| PDB | External Database | Details |
|---|---|---|
| Ace 0 | - | acetylation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 109628.6 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1588.1 | |
| All* | Total formula weight | 111216.8 |
