PDB: 12119 resultsInfo pagesStatus searchChemie searchBIRD

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2L4Z	NMR structure of fusion of CtIP (641-685) to LMO4-LIM1 (18-82) Descriptor: DNA endonuclease RBBP8,LIM domain transcription factor LMO4, ZINC ION Authors: Liew, C, Stokes, P.H, Kwan, A.H, Matthews, J.M. Deposit date: 2010-10-22 Release date: 2011-10-26 Last modified: 2024-05-29 Method: SOLUTION NMR Cite: Structural Basis of the Interaction of the Breast Cancer Oncogene LMO4 with the Tumour Suppressor CtIP/RBBP8. J.Mol.Biol., 425, 2013
2LEF	LEF1 HMG DOMAIN (FROM MOUSE), COMPLEXED WITH DNA (15BP), NMR, 12 STRUCTURES Descriptor: DNA (5'-D(*CP*AP*CP*CP*CP*TP*TP*TP*GP*AP*AP*GP*CP*TP*C)-3'), DNA (5'-D(*GP*AP*GP*CP*TP*TP*CP*AP*AP*AP*GP*GP*GP*TP*G)-3'), PROTEIN (LYMPHOID ENHANCER-BINDING FACTOR) Authors: Li, X, Love, J.J, Case, D.A, Wright, P.E. Deposit date: 1998-10-13 Release date: 1998-10-21 Last modified: 2023-12-27 Method: SOLUTION NMR Cite: Structural basis for DNA bending by the architectural transcription factor LEF-1. Nature, 376, 1995
2LJ9	Partial 3d structure of the c-terminal part of the free arabidopsis thaliana cp12-2 in its oxidized form Descriptor: CP12 domain-containing protein 2 Authors: Trivelli, X, Sparla, F, Marri, L, Trost, P. Deposit date: 2011-09-09 Release date: 2012-04-25 Last modified: 2012-06-27 Method: SOLUTION NMR Cite: Conformational Selection and Folding-upon-binding of Intrinsically Disordered Protein CP12 Regulate Photosynthetic Enzymes Assembly. J.Biol.Chem., 287, 2012
2LJL	NMR structure of Hsp12 in the presence of DPC Descriptor: 12 kDa heat shock protein Authors: Singarapu, K, Markley, J, Center for Eukaryotic Structural Genomics (CESG) Deposit date: 2011-09-20 Release date: 2011-10-12 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Structural characterization of Hsp12, the heat shock protein from Saccharomyces cerevisiae, in aqueous solution where it is intrinsically disordered and in detergent micelles where it is locally alpha-helical. J.Biol.Chem., 286, 2011
1E99	Human thymidylate kinase complexed with AZTMP and ADP Descriptor: 3'-AZIDO-3'-DEOXYTHYMIDINE-5'-MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... Authors: Ostermann, N, Lavie, A, Padiyar, S, Brundiers, R, Veit, T, Reinstein, J, Goody, R.S, Konrad, M, Schlichting, I. Deposit date: 2000-10-10 Release date: 2001-10-05 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Potentiating Azt Activation: Structures of Wildtype and Mutant Human Thymidylate Kinase Suggest Reasons for the Mutants' Improved Kinetics with the HIV Prodrug Metabolite Aztmp J.Mol.Biol., 304, 2000
1E98	Wild type human thymidylate kinase complexed with AZTMP and ADP Descriptor: 3'-AZIDO-3'-DEOXYTHYMIDINE-5'-MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... Authors: Ostermann, N, Lavie, A, Padiyar, S, Brundiers, R, Veit, T, Reintein, J, Goody, R.S, Konrad, M, Schlichting, I. Deposit date: 2000-10-10 Release date: 2001-10-05 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Potentiating Azt Activation: Structures of Wildtype and Mutant Human Thymidylate Kinase Suggest Reasons for the Mutants' Improved Kinetics with the HIV Prodrug Metabolite Aztmp J.Mol.Biol., 304, 2000
1E9B	Human thymidylate kinase complexed with AZTMP and APPNP Descriptor: 3'-AZIDO-3'-DEOXYTHYMIDINE-5'-MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... Authors: Ostermann, N, Lavie, A, Padiyar, S, Brundiers, R, Veit, T, Reintein, J, Goody, R.S, Konrad, M, Schlichting, I. Deposit date: 2000-10-10 Release date: 2001-10-05 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Potentiating Azt Activation: Structures of Wildtype and Mutant Human Thymidylate Kinase Suggest Reasons for the Mutants' Improved Kinetics with the HIV Prodrug Metabolite Aztmp J.Mol.Biol., 304, 2000
3I6W	Structure and Activation Mechanism of the CHK2 DNA-Damage Checkpoint Kinase Descriptor: Serine/threonine-protein kinase Chk2 Authors: Pavletich, N.P. Deposit date: 2009-07-07 Release date: 2009-11-10 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (3.25 Å) Cite: Structure and activation mechanism of the CHK2 DNA damage checkpoint kinase. Mol.Cell, 35, 2009
3I6U	Structure and Activation Mechanism of the CHK2 DNA-Damage Checkpoint Kinase Descriptor: Serine/threonine-protein kinase Chk2 Authors: Pavletich, N.P. Deposit date: 2009-07-07 Release date: 2009-11-10 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (3 Å) Cite: Structure and activation mechanism of the CHK2 DNA damage checkpoint kinase. Mol.Cell, 35, 2009
1FP4	CRYSTAL STRUCTURE OF THE ALPHA-H195Q MUTANT OF NITROGENASE Descriptor: 3-HYDROXY-3-CARBOXY-ADIPIC ACID, CALCIUM ION, FE-MO-S CLUSTER, ... Authors: Sorlie, M, Christiansen, J, Lemon, B.J, Peters, J.W, Dean, D.R, Hales, B.J. Deposit date: 2000-08-30 Release date: 2002-11-20 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Mechanistic features and structure of the nitrogenase alpha-Gln195 MoFe protein Biochemistry, 40, 2001
3J9T	Yeast V-ATPase state 1 Descriptor: V-type proton ATPase catalytic subunit A, V-type proton ATPase subunit B, V-type proton ATPase subunit C, ... Authors: Zhao, J, Benlekbir, S, Rubinstein, J.L. Deposit date: 2015-02-23 Release date: 2015-05-13 Last modified: 2024-02-21 Method: ELECTRON MICROSCOPY (6.9 Å) Cite: Electron cryomicroscopy observation of rotational states in a eukaryotic V-ATPase. Nature, 521, 2015
3K2L	Crystal Structure of dual-specificity tyrosine phosphorylation regulated kinase 2 (DYRK2) Descriptor: CHLORIDE ION, Dual specificity tyrosine-phosphorylation-regulated kinase 2, SODIUM ION, ... Authors: Filippakopoulos, P, Myrianthopoulos, V, Soundararajan, M, Krojer, T, Hapka, E, Fedorov, O, Berridge, G, Wang, J, Shrestha, L, Pike, A.C.W, Ugochukwu, E, von Delft, F, Arrowsmith, C.H, Edwards, A, Weigelt, J, Bountra, C, Mikros, E, Knapp, S, Structural Genomics Consortium (SGC) Deposit date: 2009-09-30 Release date: 2009-10-13 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.36 Å) Cite: Structures of Down Syndrome Kinases, DYRKs, Reveal Mechanisms of Kinase Activation and Substrate Recognition. Structure, 21, 2013
3J9V	Yeast V-ATPase state 3 Descriptor: V-type proton ATPase catalytic subunit A, V-type proton ATPase subunit B, V-type proton ATPase subunit C, ... Authors: Zhao, J, Benlekbir, S, Rubinstein, J.L. Deposit date: 2015-02-23 Release date: 2015-05-13 Last modified: 2024-02-21 Method: ELECTRON MICROSCOPY (8.3 Å) Cite: Electron cryomicroscopy observation of rotational states in a eukaryotic V-ATPase. Nature, 521, 2015
3J9U	Yeast V-ATPase state 2 Descriptor: V-type proton ATPase catalytic subunit A, V-type proton ATPase subunit B, V-type proton ATPase subunit C, ... Authors: Zhao, J, Benlekbir, S, Rubinstein, J.L. Deposit date: 2015-02-23 Release date: 2015-05-13 Last modified: 2024-02-21 Method: ELECTRON MICROSCOPY (7.6 Å) Cite: Electron cryomicroscopy observation of rotational states in a eukaryotic V-ATPase. Nature, 521, 2015
1GGW	CDC4P FROM SCHIZOSACCHAROMYCES POMBE Descriptor: PROTEIN (CDC4P) Authors: Slupsky, C.M, Hemmingsen, S.M, McIntosh, L.P. Deposit date: 2000-09-25 Release date: 2001-03-21 Last modified: 2023-12-27 Method: SOLUTION NMR Cite: Structure of Cdc4p, a contractile ring protein essential for cytokinesis in Schizosaccharomyces pombe. J.Biol.Chem., 276, 2001
3KVW	Crystal Structure of dual-specificity tyrosine phosphorylation regulated kinase 2 (DYRK2) in complex with an indirubin ligand Descriptor: (2Z,3E)-7'-bromo-3-(hydroxyimino)-2'-oxo-1,1',2',3-tetrahydro-2,3'-biindole-5-carboxylic acid, CHLORIDE ION, Dual specificity tyrosine-phosphorylation-regulated kinase 2 Authors: Filippakopoulos, P, Myrianthopoulos, V, Kritsanida, M, Magiatis, P, Skaltsounis, A.L, Soundararajan, M, Krojer, T, Gileadi, O, Hapka, E, Fedorov, O, Berridge, G, Wang, J, Shrestha, L, Vollmar, M, von Delft, F, Arrowsmith, C.H, Edwards, A, Weigelt, J, Bountra, C, Mikros, E, Knapp, S, Structural Genomics Consortium (SGC) Deposit date: 2009-11-30 Release date: 2010-01-05 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.28 Å) Cite: Crystal Structure of dual-specificity tyrosine phosphorylation regulated kinase 2 (DYRK2) in complex with an indirubin ligand To be Published
1H6O	Dimerisation domain from human TRF1 Descriptor: TELOMERIC REPEAT BINDING FACTOR 1 Authors: Fairall, L, Chapman, L, Rhodes, D. Deposit date: 2001-06-20 Release date: 2001-09-05 Last modified: 2024-04-24 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Structure of the TRFH dimerization domain of the human telomeric proteins TRF1 and TRF2. Mol.Cell, 8, 2001
1H6P	Dimeristion domain from human TRF2 Descriptor: MAGNESIUM ION, TELOMERIC REPEAT BINDING FACTOR 2 Authors: Chapman, L, Fairall, L, Rhodes, D. Deposit date: 2001-06-20 Release date: 2001-09-05 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structure of the Trfh Dimerization Domain of the Human Telomere Proteins Trf1 and Trf2 Mol.Cell, 8, 2001
1HS1	SOLUTION STRUCTURE OF RNA HAIRPIN LOOP UUAACU AS PART OF HAIRPIN R(GCGUUAACUCGCA) Descriptor: 5'-R(*GP*CP*GP*UP*UP*AP*AP*CP*UP*CP*GP*CP*A)-3' Authors: Zhang, H, Culyba, M, Volkman, H, Krugh, T.R. Deposit date: 2000-12-22 Release date: 2003-09-02 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Structural Characterization of Six-Nucleotide RNA Hairpin loops: r(UUAAUU), r(UUAAAU), r(UUAACU) To be Published
1HS3	SOLUTION STRUCTURE OF RNA HAIRPIN LOOP UUAAUU AS PART OF HAIRPIN R(GCGUUAAUUCGCA) Descriptor: 5'-R(*GP*CP*GP*UP*UP*AP*AP*UP*UP*CP*GP*CP*A)-3' Authors: Zhang, H, Culyba, M, Volkman, H, Krugh, T.R. Deposit date: 2000-12-22 Release date: 2003-09-02 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Structural Characterization of Six-Nucleotide RNA Hairpin loops: r(UUAAUU), r(UUAAAU), r(UUAACU) To be Published
1HS8	SOLUTION STRUCTURE OF RNA HAIRPIN LOOP UCAAUU AS PART OF HAIRPIN R(GCGUCAAUUCGCA) Descriptor: 5'-R(*GP*CP*GP*UP*CP*AP*AP*UP*UP*CP*GP*CP*A)-3' Authors: Zhang, H, Ricart, B, Huck, M, Krugh, T.R. Deposit date: 2000-12-25 Release date: 2003-09-02 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Structural Characterization of Six-Nucleotide RNA Hairpin loops r(UCAAUU) To be Published
1HS2	SOLUTION STRUCTURE OF RNA HAIRPIN LOOP UUAAGU AS PART OF HAIRPIN R(GCGUUAAGUCGCA) Descriptor: 5'-R(*GP*CP*GP*UP*UP*AP*AP*GP*UP*CP*GP*CP*A)-3' Authors: Zhang, H, Fountain, M.A, Krugh, T.R. Deposit date: 2000-12-22 Release date: 2001-08-29 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Structural characterization of a six-nucleotide RNA hairpin loop found in Escherichia coli, r(UUAAGU). Biochemistry, 40, 2001
1HS4	SOLUTION STRUCTURE OF RNA HAIRPIN LOOP UUAAAU AS PART OF HAIRPIN R(GCGUUAAAUCGCA) Descriptor: 5'-R(*GP*CP*GP*UP*UP*AP*AP*AP*UP*CP*GP*CP*A)-3' Authors: Zhang, H, Culyba, M, Volkman, H, Krugh, T.R. Deposit date: 2000-12-22 Release date: 2003-09-02 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Structural Characterization of Six-Nucleotide RNA Hairpin loops: r(UUAAUU), r(UUAAAU), r(UUAACU) To be Published
3L82	X-ray Crystal structure of TRF1 and Fbx4 complex Descriptor: F-box only protein 4, Telomeric repeat-binding factor 1 Authors: Zeng, Z.X, Wang, W, Yang, Y.T, Chen, Y, Yang, X.M, Diehl, J.A, Liu, X.D, Lei, M. Deposit date: 2009-12-29 Release date: 2010-03-09 Last modified: 2013-09-25 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structural Basis of Selective Ubiquitination of TRF1 by SCF(Fbx4) Dev.Cell, 18, 2010
6RML	Crystal structure of TOPBP1 BRCT0,1,2 in complex with a 53BP1 phosphopeptide Descriptor: 53BP1, DNA topoisomerase 2-binding protein 1 Authors: Day, M, Oliver, A.W, Pearl, L.H. Deposit date: 2019-05-07 Release date: 2019-06-12 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.81 Å) Cite: Phosphorylation-mediated interactions with TOPBP1 couple 53BP1 and 9-1-1 to control the G1 DNA damage checkpoint. Elife, 8, 2019

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