2QFU
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1EQM
| CRYSTAL STRUCTURE OF BINARY COMPLEX OF 6-HYDROXYMETHYL-7,8-DIHYDROPTERIN PYROPHOSPHOKINASE WITH ADENOSINE-5'-DIPHOSPHATE | Descriptor: | 6-HYDROXYMETHYL-7,8-DIHYDROPTERIN PYROPHOSPHOKINASE, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Xiao, B, Blaszczyk, J, Ji, X. | Deposit date: | 2000-04-05 | Release date: | 2001-04-05 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Unusual conformational changes in 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase as revealed by X-ray crystallography and NMR. J.Biol.Chem., 276, 2001
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1HRA
| THE SOLUTION STRUCTURE OF THE HUMAN RETINOIC ACID RECEPTOR-BETA DNA-BINDING DOMAIN | Descriptor: | RETINOIC ACID RECEPTOR, ZINC ION | Authors: | Knegtel, R.M.A, Katahira, M, Schilthuis, J.G, Bonvin, A.M.J.J, Boelens, R, Eib, D, Van Der Saag, P.T, Kaptein, R. | Deposit date: | 1993-07-25 | Release date: | 1994-01-31 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | The solution structure of the human retinoic acid receptor-beta DNA-binding domain. J.Biomol.NMR, 3, 1993
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2QTW
| The Crystal Structure of PCSK9 at 1.9 Angstroms Resolution Reveals structural homology to Resistin within the C-terminal domain | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Proprotein convertase subtilisin/kexin type 9, ... | Authors: | Hampton, E.N, Knuth, M.W, Li, J, Harris, J.L, Lesley, S.A, Spraggon, G. | Deposit date: | 2007-08-02 | Release date: | 2007-09-18 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The self-inhibited structure of full-length PCSK9 at 1.9 A reveals structural homology with resistin within the C-terminal domain. Proc.Natl.Acad.Sci.Usa, 104, 2007
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1F4Q
| CRYSTAL STRUCTURE OF APO GRANCALCIN | Descriptor: | GRANCALCIN | Authors: | Jia, J, Han, Q, Borregaard, N, Lollike, K, Cygler, M. | Deposit date: | 2000-06-08 | Release date: | 2000-09-27 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of human grancalcin, a member of the penta-EF-hand protein family. J.Mol.Biol., 300, 2000
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1EPH
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4HVA
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1RMQ
| Crystal structure of AphA class B acid phosphatase/phosphotransferase with osmiate mimicking the catalytic intermediate | Descriptor: | COBALT (II) ION, Class B acid phosphatase, OSMIUM ION | Authors: | Calderone, V, Forleo, C, Benvenuti, M, Rossolini, G.M, Thaller, M.C, Mangani, S. | Deposit date: | 2003-11-28 | Release date: | 2004-12-14 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Insights in the catalytic mechanism of AphA from Escherichia coli To be Published
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1BRP
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3RH5
| DNA Polymerase Beta Mutant (Y271) with a dideoxy-terminated primer with an incoming deoxynucleotide (dCTP) | Descriptor: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 5'-D(*CP*CP*GP*AP*CP*GP*CP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(DDG))-3', ... | Authors: | Cavanaugh, N.A, Beard, W.A, Batra, V.K, Perera, L, Pedersen, L.G, Wilson, S.H. | Deposit date: | 2011-04-11 | Release date: | 2011-07-06 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.096 Å) | Cite: | Molecular insights into DNA polymerase deterrents for ribonucleotide insertion. J.Biol.Chem., 286, 2011
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2R6W
| Estrogen receptor alpha ligand-binding domain complexed to a SERM | Descriptor: | Estrogen receptor, [6-hydroxy-2-(4-hydroxyphenyl)-1-benzothien-3-yl]{4-[2-(4-methylpiperidin-1-yl)ethoxy]phenyl}methanone | Authors: | Wang, Y. | Deposit date: | 2007-09-06 | Release date: | 2008-04-08 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Prediction of the tissue-specificity of selective estrogen receptor modulators by using a single biochemical method. Proc.Natl.Acad.Sci.Usa, 105, 2008
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1BRQ
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2LQL
| Solution structure of CHCH5 | Descriptor: | Coiled-coil-helix-coiled-coil-helix domain-containing protein 5 | Authors: | Peruzzini, R, Ciofi-Baffoni, S, Banci, L, Bertini, I. | Deposit date: | 2012-03-09 | Release date: | 2012-10-24 | Last modified: | 2023-12-06 | Method: | SOLUTION NMR | Cite: | Structural characterization of CHCHD5 and CHCHD7: Two atypical human twin CX(9)C proteins. J.Struct.Biol., 180, 2012
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1IDW
| STRUCTURE OF THE HYBRID RNA/DNA R-GCUUCGGC-D[CL]U IN PRESENCE OF RH(NH3)6+++ | Descriptor: | 5'-R(*GP*CP*UP*UP*CP*GP*GP*C)-D(P*(UCL))-3', CHLORIDE ION, RHODIUM HEXAMINE ION | Authors: | Cruse, W, Saludjian, P, Neuman, A, Prange, T. | Deposit date: | 2001-04-05 | Release date: | 2001-04-12 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Destabilizing effect of a fluorouracil extra base in a hybrid RNA duplex compared with bromo and chloro analogues Acta Crystallogr.,Sect.D, 57, 2001
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1S32
| Molecular Recognition of the Nucleosomal 'Supergroove' | Descriptor: | 2-(2-CARBAMOYLMETHOXY-ETHOXY)-ACETAMIDE, 3-AMINO-(DIMETHYLPROPYLAMINE), 4-AMINO-(1-METHYLIMIDAZOLE)-2-CARBOXYLIC ACID, ... | Authors: | Edayathumangalam, R.S, Weyermann, P, Gottesfeld, J.M, Dervan, P.B, Luger, K. | Deposit date: | 2004-01-12 | Release date: | 2004-05-11 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Molecular Recognition of the Nucleosomal 'Supergroove' Proc.Natl.Acad.Sci.USA, 101, 2004
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1IHA
| Structure of the Hybrid RNA/DNA R-GCUUCGGC-D[BR]U in Presence of RH(NH3)6+++ | Descriptor: | 5'-R(*GP*CP*UP*UP*CP*GP*GP*C)-D(P*(BRU))-3', CHLORIDE ION, RHODIUM HEXAMINE ION | Authors: | Cruse, W.B, Saludjian, P, Neuman, A, Prange, T. | Deposit date: | 2001-04-19 | Release date: | 2001-05-07 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Destabilizing effect of a fluorouracil extra base in a hybrid RNA duplex compared with bromo and chloro analogues. Acta Crystallogr.,Sect.D, 57, 2001
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2L07
| 1H, 13C, and 15N chemical shifts and structure of brazzein-derived peptide CKR-PNG | Descriptor: | Defensin-like protein | Authors: | Dittli, S.M, Assadi-Porter, F.M, Rao, H, Tonelli, M. | Deposit date: | 2010-06-30 | Release date: | 2011-06-22 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Structural role of the terminal disulfide bond in the sweetness of brazzein. Chem Senses, 36, 2011
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1J5O
| CRYSTAL STRUCTURE OF MET184ILE MUTANT OF HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH DOUBLE STRANDED DNA TEMPLATE-PRIMER | Descriptor: | 5'-D(*AP*TP*GP*GP*CP*GP*CP*CP*CP*GP*AP*AP*CP*AP*GP*GP*GP*AP*C)-3', 5'-D(*GP*TP*CP*CP*CP*TP*GP*TP*TP*CP*GP*GP*GP*CP*GP*CP*CP*A)-3', ANTIBODY (HEAVY CHAIN), ... | Authors: | Sarafianos, S.G, Das, K, Arnold, E. | Deposit date: | 2002-05-24 | Release date: | 2002-06-14 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Lamivudine (3TC) resistance in HIV-1 reverse transcriptase involves steric hindrance with beta-branched amino acids. Proc.Natl.Acad.Sci.USA, 96, 1999
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2R6Y
| Estrogen receptor alpha ligand-binding domain in complex with a SERM | Descriptor: | Estrogen receptor, [6-hydroxy-2-(4-hydroxyphenyl)-1-benzothien-3-yl][4-(2-pyrrolidin-1-ylethoxy)phenyl]methanone | Authors: | Wang, Y. | Deposit date: | 2007-09-06 | Release date: | 2008-04-08 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Prediction of the tissue-specificity of selective estrogen receptor modulators by using a single biochemical method. Proc.Natl.Acad.Sci.Usa, 105, 2008
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1EQG
| THE 2.6 ANGSTROM MODEL OF OVINE COX-1 COMPLEXED WITH IBUPROFEN | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, IBUPROFEN, PROSTAGLANDIN H2 SYNTHASE-1, ... | Authors: | Loll, P.J, Selinsky, B.S, Gupta, K, Sharkey, C.T. | Deposit date: | 2000-04-04 | Release date: | 2001-04-11 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.61 Å) | Cite: | Structural analysis of NSAID binding by prostaglandin H2 synthase: time-dependent and time-independent inhibitors elicit identical enzyme conformations. Biochemistry, 40, 2001
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3QI5
| Crystal structure of human alkyladenine DNA glycosylase in complex with 3,N4-ethenocystosine containing duplex DNA | Descriptor: | DNA (5'-D(*GP*AP*CP*AP*TP*GP*(EDC)P*TP*TP*GP*CP*CP*T)-3'), DNA (5'-D(*GP*GP*CP*AP*AP*GP*CP*AP*TP*GP*TP*CP*A)-3'), DNA-3-methyladenine glycosylase, ... | Authors: | Lingaraju, G.M, Davis, C.A, Setser, J.W, Samson, L.D, Drennan, C.L. | Deposit date: | 2011-01-26 | Release date: | 2011-03-09 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural Basis for the Inhibition of Human Alkyladenine DNA Glycosylase (AAG) by 3,N4-Ethenocytosine-containing DNA. J.Biol.Chem., 286, 2011
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7O2W
| Structure of the C9orf72-SMCR8 complex | Descriptor: | Guanine nucleotide exchange protein SMCR8,Guanine nucleotide exchange protein SMCR8,Maltose/maltodextrin-binding periplasmic protein, Ubiquitin-like protein SMT3,Guanine nucleotide exchange C9orf72 | Authors: | Noerpel, J, Cavadini, S, Schenk, A.D, Graff-Meyer, A, Chao, J, Bhaskar, V. | Deposit date: | 2021-03-31 | Release date: | 2021-07-21 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY | Cite: | Structure of the human C9orf72-SMCR8 complex reveals a multivalent protein interaction architecture. Plos Biol., 19, 2021
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5IP7
| Structure of RNA Polymerase II-Tfg1 peptide complex | Descriptor: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | Authors: | Plaschka, C, Hantsche, M, Dienemann, C, Burzinski, C, Plitzko, J, Cramer, P. | Deposit date: | 2016-03-09 | Release date: | 2016-05-11 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.52 Å) | Cite: | Transcription initiation complex structures elucidate DNA opening. Nature, 533, 2016
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3IK1
| Lactobacillus casei Thymidylate Synthase in Ternary Complex with dUMP and the Phtalimidic Derivative 20C | Descriptor: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 2-hydroxy-4-(4-methyl-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)benzoic acid, Thymidylate synthase | Authors: | Pozzi, C, Cancian, L, Leone, R, Luciani, R, Ferrari, S, Mangani, S, Costi, M.P. | Deposit date: | 2009-08-05 | Release date: | 2010-08-11 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Identification of the binding modes of N-phenylphthalimides inhibiting bacterial thymidylate synthase through X-ray crystallography screening J.Med.Chem., 54, 2011
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1EBV
| OVINE PGHS-1 COMPLEXED WITH SALICYL HYDROXAMIC ACID | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETIC ACID SALICYLOYL-AMINO-ESTER, ... | Authors: | Loll, P.J, Sharkey, C.T, O'Connor, S.J, Fitzgerald, D.J. | Deposit date: | 2000-01-24 | Release date: | 2000-02-24 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | O-acetylsalicylhydroxamic acid, a novel acetylating inhibitor of prostaglandin H2 synthase: structural and functional characterization of enzyme-inhibitor interactions. Mol.Pharmacol., 60, 2001
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