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1EBV

OVINE PGHS-1 COMPLEXED WITH SALICYL HYDROXAMIC ACID

Summary for 1EBV
Entry DOI10.2210/pdb1ebv/pdb
DescriptorPROSTAGLANDIN H2 SYNTHASE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
Functional Keywordsmonotopic membrane protein, oxidoreductase
Biological sourceOvis aries (sheep)
Total number of polymer chains1
Total formula weight65232.45
Authors
Loll, P.J.,Sharkey, C.T.,O'Connor, S.J.,Fitzgerald, D.J. (deposition date: 2000-01-24, release date: 2000-02-24, Last modification date: 2020-07-29)
Primary citationLoll, P.J.,Sharkey, C.T.,O'Connor, S.J.,Dooley, C.M.,O'Brien, E.,Devocelle, M.,Nolan, K.B.,Selinsky, B.S.,Fitzgerald, D.J.
O-acetylsalicylhydroxamic acid, a novel acetylating inhibitor of prostaglandin H2 synthase: structural and functional characterization of enzyme-inhibitor interactions.
Mol.Pharmacol., 60:1407-1413, 2001
Cited by
PubMed: 11723249
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.2 Å)
Structure validation

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