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6T17
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BU of 6t17 by Molmil
Cryo-EM structure of the wild-type flagellar filament of the Firmicute Kurthia
Descriptor: Flagellin
Authors:Blum, T.B, Abrahams, J.P.
Deposit date:2019-10-03
Release date:2019-10-30
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:The wild-type flagellar filament of the Firmicute Kurthia at 2.8 angstrom resolution in vivo.
Sci Rep, 9, 2019
6PLC
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BU of 6plc by Molmil
Structure of human DNA polymerase eta complexed with 8OA in the template base paired with incoming non-hydrolyzable GTP
Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*(A38)P*AP*TP*GP*AP*CP*GP*CP*T)-3'), ...
Authors:Koag, M.C, Lee, S.
Deposit date:2019-06-30
Release date:2020-04-22
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Mutagenesis mechanism of the major oxidative adenine lesion 7,8-dihydro-8-oxoadenine.
Nucleic Acids Res., 48, 2020
1GM5
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BU of 1gm5 by Molmil
Structure of RecG bound to three-way DNA junction
Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA (5'-(*CP*AP*GP*CP*TP*CP*CP*AP*TP*GP*AP*TP* CP*AP*TP*TP*GP*GP*CP*A)-3'), DNA (5'-(*GP*AP*GP*CP*AP*CP*TP*GP*C)-3'), ...
Authors:Singleton, M.R, Scaife, S, Wigley, D.B.
Deposit date:2001-09-11
Release date:2001-10-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.24 Å)
Cite:Structural Analysis of DNA Replication Fork Reversal by Recg
Cell(Cambridge,Mass.), 107, 2001
4WIF
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BU of 4wif by Molmil
Crystal structure of E47Q mutant cytidine deaminase from Mycobacterium tuberculosis (MtCDA E47Q)
Descriptor: Cytidine deaminase, ZINC ION
Authors:Trivella, D.B, Sanchez-Quitian, A.Z, Basso, L.A, Santos, D.S.
Deposit date:2014-09-25
Release date:2015-09-09
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of E47Q mutant cytidine deaminase from Mycobacterium tuberculosis (MtCDA E47Q)
Rsc Adv, 2015
4WIG
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BU of 4wig by Molmil
Crystal structure of E47D mutant cytidine deaminase from Mycobacterium tuberculosis (MtCDA E47D)
Descriptor: Cytidine deaminase, ZINC ION
Authors:Trivella, D.B.B, Sanchez-Quitian, A.Z, Basso, L.A, Santos, D.S.
Deposit date:2014-09-25
Release date:2015-08-12
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.758 Å)
Cite:Functional and structural evidence for the catalytic role played by glutamate-47 residue in the mode of action of Mycobacterium tuberculosis cytidine deaminase
Rsc Adv, 5, 2015
8UZ0
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BU of 8uz0 by Molmil
Straight actin filament from Arp2/3 branch junction sample (ADP)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Chavali, S.S, Chou, S.Z, Sindelar, C.V.
Deposit date:2023-11-14
Release date:2024-01-31
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Cryo-EM structures reveal how phosphate release from Arp3 weakens actin filament branches formed by Arp2/3 complex.
Nat Commun, 15, 2024
5FUE
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BU of 5fue by Molmil
Crystal structure of Schistosoma mansoni HDAC8 complexed with 3- benzamido-benzohydroxamate
Descriptor: 3-(benzoylamino)-N-oxobenzamide, DIMETHYLFORMAMIDE, GLYCEROL, ...
Authors:Marek, M, Romier, C.
Deposit date:2016-01-26
Release date:2016-03-09
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.199 Å)
Cite:Structure-Based Design and Synthesis of Novel Inhibitors Targeting Hdac8 from Schistosoma Mansoni for the Treatment of Schistosomiasis.
J.Med.Chem., 59, 2016
7U69
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BU of 7u69 by Molmil
Crystal Structure of Danio rerio Histone Deacetylase 10 in Complex with Phenethyl Piperidine-4-acrylhydroxamic Acid Inhibitor
Descriptor: (2E)-N-hydroxy-3-[1-(2-phenylethyl)piperidin-4-yl]prop-2-enamide, PHOSPHATE ION, POTASSIUM ION, ...
Authors:Herbst-Gervasoni, C.J, Christianson, D.W.
Deposit date:2022-03-03
Release date:2022-04-06
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Identification of histone deacetylase 10 (HDAC10) inhibitors that modulate autophagy in transformed cells.
Eur.J.Med.Chem., 234, 2022
7U6A
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BU of 7u6a by Molmil
Crystal Structure of Danio rerio Histone Deacetylase 10 in Complex with 3-thienylmethyl Benzhydroxamic Acid Inhibitor
Descriptor: 1,2-ETHANEDIOL, N-hydroxy-4-({[(thiophen-3-yl)methyl]amino}methyl)benzamide, PHOSPHATE ION, ...
Authors:Herbst-Gervasoni, C.J, Christianson, D.W.
Deposit date:2022-03-03
Release date:2022-04-06
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Identification of histone deacetylase 10 (HDAC10) inhibitors that modulate autophagy in transformed cells.
Eur.J.Med.Chem., 234, 2022
7U3M
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BU of 7u3m by Molmil
Crystal Structure of Danio rerio Histone Deacetylase 10 in Complex with N-methylpiperazine Benzhydroxamic Acid
Descriptor: N-hydroxy-4-[(4-methylpiperazin-1-yl)methyl]benzamide, PHOSPHATE ION, POTASSIUM ION, ...
Authors:Herbst-Gervasoni, C.J, Christianson, D.W.
Deposit date:2022-02-27
Release date:2022-04-06
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Identification of histone deacetylase 10 (HDAC10) inhibitors that modulate autophagy in transformed cells.
Eur.J.Med.Chem., 234, 2022
7U6B
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BU of 7u6b by Molmil
Crystal Structure of Danio rerio Histone Deacetylase 10 in Complex with Indolethyl Piperidine-4-acrylhydroxamic Acid Inhibitor
Descriptor: (2E)-N-hydroxy-3-{1-[2-(1H-indol-3-yl)ethyl]piperidin-4-yl}prop-2-enamide, PHOSPHATE ION, POTASSIUM ION, ...
Authors:Herbst-Gervasoni, C.J, Christianson, D.W.
Deposit date:2022-03-03
Release date:2022-04-06
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Identification of histone deacetylase 10 (HDAC10) inhibitors that modulate autophagy in transformed cells.
Eur.J.Med.Chem., 234, 2022
5CNQ
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BU of 5cnq by Molmil
Crystal structure of the Holliday junction-resolving enzyme GEN1 (WT) in complex with product DNA, Mg2+ and Mn2+ ions
Descriptor: DNA (5'-D(*TP*GP*AP*GP*CP*GP*GP*TP*GP*GP*TP*TP*GP*GP*T)-3'), MANGANESE (II) ION, Nuclease-like protein, ...
Authors:Liu, Y.J, Freeman, A.D.J, Declais, A.C, Wilson, T.J, Gartner, A, Lilley, D.M.J.
Deposit date:2015-07-17
Release date:2015-12-30
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.602 Å)
Cite:Crystal Structure of a Eukaryotic GEN1 Resolving Enzyme Bound to DNA.
Cell Rep, 13, 2015
5CO8
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BU of 5co8 by Molmil
Crystal structure of the Holliday junction-resolving enzyme GEN1 (WT) in complex with product DNA and Mg2+ ion
Descriptor: DNA (31-MER), DNA (5'-D(*AP*GP*AP*CP*TP*GP*CP*AP*GP*TP*TP*GP*AP*GP*TP*C)-3'), DNA (5'-D(*TP*GP*AP*GP*CP*GP*GP*TP*GP*GP*TP*TP*GP*GP*A)-3'), ...
Authors:Liu, Y.J, Freeman, A.D.J, Declais, A.C, Wilson, T.J, Gartner, A, Lilley, D.M.J.
Deposit date:2015-07-20
Release date:2016-01-13
Last modified:2018-11-21
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structure of a Eukaryotic GEN1 Resolving Enzyme Bound to DNA.
Cell Rep, 13, 2015
7EYC
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BU of 7eyc by Molmil
Crystal structure of Tau and acetylated tau peptide antigen
Descriptor: ACETYLATED TAU PEPTIDE, antibody, Heavy chain, ...
Authors:Hong, M, Park, J.
Deposit date:2021-05-30
Release date:2022-06-01
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Monoclonal antibody Y01 prevents tauopathy progression induced by lysine 280-acetylated tau in cell and mouse models.
J.Clin.Invest., 133, 2023
5GMJ
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BU of 5gmj by Molmil
Crystal Structure of GRASP55 GRASP domain in complex with JAM-B C-terminus
Descriptor: Golgi reassembly-stacking protein 2, Junctional adhesion molecule B
Authors:Shi, N, Shi, X, Morelli, X, Betzi, S, Huang, X.
Deposit date:2016-07-14
Release date:2017-05-24
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.986 Å)
Cite:Genetic, structural, and chemical insights into the dual function of GRASP55 in germ cell Golgi remodeling and JAM-C polarized localization during spermatogenesis
PLoS Genet., 13, 2017
7FGN
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BU of 7fgn by Molmil
The crystal structure of the FAF1 UBL1
Descriptor: FAS-associated factor 1
Authors:Kim, E.E, ParK, J.K, Shin, S.C.
Deposit date:2021-07-27
Release date:2022-07-27
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.199 Å)
Cite:The complex of Fas-associated factor 1 with Hsp70 stabilizes the adherens junction integrity by suppressing RhoA activation
J Mol Cell Biol, 14, 2022
7FGM
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BU of 7fgm by Molmil
The complex crystals structure of the FAF1 UBL1_L-Hsp70 NBD with ADP and phosphate
Descriptor: ADENOSINE-5'-DIPHOSPHATE, FAS-associated factor 1, Heat shock 70 kDa protein 1A, ...
Authors:Kim, E.E, ParK, J.K, Shin, S.C.
Deposit date:2021-07-27
Release date:2022-07-27
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The complex of Fas-associated factor 1 with Hsp70 stabilizes the adherens junction integrity by suppressing RhoA activation
J Mol Cell Biol, 14, 2022
1DXN
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BU of 1dxn by Molmil
The Solution Structure of [d(CGC)r(aaa)d(TTTGCG)]2: Hybrid Junctions Flanked by DNA Duplexes
Descriptor: DNA/RNA (5'-D(*CP*GP*CP)-R(*AP*AP*AP)-D(*TP*TP*TP*GP*CP*G)-3')
Authors:Hsu, S.-T, Chou, M.-T, Cheng, J.-W.
Deposit date:2000-01-11
Release date:2000-04-11
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Hydration of [D(Cgc)R(Aaa)D(Tttgcg)]2
J.Mol.Biol., 295, 2000
1E7L
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BU of 1e7l by Molmil
Endonuclease VII (EndoVII) N62D mutant from phage T4
Descriptor: RECOMBINATION ENDONUCLEASE VII, SULFATE ION, ZINC ION
Authors:Raaijmakers, H.C.A, Vix, O, Toro, I, Suck, D.
Deposit date:2000-08-29
Release date:2001-05-04
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.32 Å)
Cite:Conformational Flexibility in T4 Endonuclease Vii Revealed by Crystallography: Implications for Substrate Binding and Cleavage
J.Mol.Biol., 308, 2001
1E7D
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BU of 1e7d by Molmil
Endonuclease VII (ENDOVII) Ffrom Phage T4
Descriptor: CALCIUM ION, CHLORIDE ION, RECOMBINATION ENDONUCLEASE VII, ...
Authors:Raaijmakers, H.C.A, Vix, O, Toro, I, Suck, D.
Deposit date:2000-08-28
Release date:2001-05-04
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Conformational Flexibility in T4 Endonuclease Vii Revealed by Crystallography: Implications for Substrate Binding and Cleavage
J.Mol.Biol., 308, 2001
8X6M
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BU of 8x6m by Molmil
Crystal Structure of Glycerol Dehydrogenase in the Presence of NAD+ and Glycerol
Descriptor: GLYCEROL, Glycerol dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:Park, T, Kang, J.Y, Jin, M, Yang, J, Kim, H, Noh, C, Eom, S.H.
Deposit date:2023-11-21
Release date:2024-03-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural insights into the octamerization of glycerol dehydrogenase.
Plos One, 19, 2024
8YRG
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BU of 8yrg by Molmil
CryoEM structure of fospropofol-bound MRGPRX4-Gq complex
Descriptor: Gs-mini-Gq chimera, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Cao, C, Fay, J.F, Roth, B.L.
Deposit date:2024-03-21
Release date:2024-05-22
Method:ELECTRON MICROSCOPY (3.14 Å)
Cite:MRGPRX4 mediates phospho-drug-associated pruritus in a humanized mouse model.
Sci Transl Med, 16, 2024
3LH5
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BU of 3lh5 by Molmil
Crystal Structure of the SH3-Guanylate kinase core domain of ZO-1
Descriptor: Tight junction protein ZO-1
Authors:Lye, M.F, Lavie, A.
Deposit date:2010-01-21
Release date:2010-03-02
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Insights into regulated ligand binding sites from the structure of ZO-1 Src homology 3-guanylate kinase module.
J.Biol.Chem., 285, 2010
6L3T
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BU of 6l3t by Molmil
Human Cx31.3/GJC3 connexin hemichannel in the absence of calcium
Descriptor: Gap junction gamma-3 protein, Lauryl Maltose Neopentyl Glycol
Authors:Lee, H.J, Jeong, H, Ryu, B, Hyun, J, Woo, J.S.
Deposit date:2019-10-15
Release date:2020-09-09
Last modified:2020-10-14
Method:ELECTRON MICROSCOPY (2.34 Å)
Cite:Cryo-EM structure of human Cx31.3/GJC3 connexin hemichannel.
Sci Adv, 6, 2020
6L3V
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BU of 6l3v by Molmil
The R15G mutant of human Cx31.3/GJC3 connexin hemichannel
Descriptor: Gap junction gamma-3 protein, Lauryl Maltose Neopentyl Glycol
Authors:Lee, H.J, Jeong, H, Ryu, B, Hyun, J, Woo, J.S.
Deposit date:2019-10-15
Release date:2020-09-09
Last modified:2020-10-14
Method:ELECTRON MICROSCOPY (2.63 Å)
Cite:Cryo-EM structure of human Cx31.3/GJC3 connexin hemichannel.
Sci Adv, 6, 2020

221716

數據於2024-06-26公開中

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