6PLC

Structure of human DNA polymerase eta complexed with 8OA in the template base paired with incoming non-hydrolyzable GTP

Summary for 6PLC

• Entry DOI: 10.2210/pdb6plc/pdb
• Descriptor: DNA polymerase eta, DNA (5'-D(*CP*AP*TP*(A38)P*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ... (7 entities in total)
• Functional Keywords: human dna polymerase, dna binding protein, dna binding protein-dna complex, dna binding protein/dna
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 3
• Total formula weight: 55353.63

Authors

Koag, M.C.,Lee, S. (deposition date: 2019-06-30, release date: 2020-04-22, Last modification date: 2023-10-11)

• Primary citation: Koag, M.C.,Jung, H.,Lee, S.; Mutagenesis mechanism of the major oxidative adenine lesion 7,8-dihydro-8-oxoadenine.; Nucleic Acids Res., 48:5119-5134, 2020; PubMed: 32282906; DOI: 10.1093/nar/gkaa193

Experimental method

X-RAY DIFFRACTION (2.5 Å)