3LH5

Crystal Structure of the SH3-Guanylate kinase core domain of ZO-1

Summary for 3LH5

• Entry DOI: 10.2210/pdb3lh5/pdb
• Descriptor: Tight junction protein ZO-1 (2 entities in total)
• Functional Keywords: zo-1, sh3-guanylate kinase, intramolecular fold, cell junction, cell membrane, membrane, phosphoprotein, sh3 domain, tight junction, protein binding
• Biological source: Homo sapiens; More
• Cellular location: Cell membrane; Peripheral membrane protein; Cytoplasmic side: Q07157
• Total number of polymer chains: 1
• Total formula weight: 29047.04

Authors

Lye, M.F.,Lavie, A. (deposition date: 2010-01-21, release date: 2010-03-02, Last modification date: 2024-02-21)

• Primary citation: Lye, M.F.,Fanning, A.S.,Su, Y.,Anderson, J.M.,Lavie, A.; Insights into regulated ligand binding sites from the structure of ZO-1 Src homology 3-guanylate kinase module.; J.Biol.Chem., 285:13907-13917, 2010; PubMed: 20200156; DOI: 10.1074/jbc.M109.093674

Experimental method

X-RAY DIFFRACTION (2.6 Å)