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6URG
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BU of 6urg by Molmil
Cryo-EM structure of human CPSF160-WDR33-CPSF30-CPSF100 PIM complex
Descriptor: Cleavage and polyadenylation specificity factor subunit 1, Cleavage and polyadenylation specificity factor subunit 2, Cleavage and polyadenylation specificity factor subunit 4, ...
Authors:Sun, Y, Zhang, Y, Walz, T, Tong, L.
Deposit date:2019-10-23
Release date:2019-11-27
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural Insights into the Human Pre-mRNA 3'-End Processing Machinery.
Mol.Cell, 77, 2020
6EK9
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BU of 6ek9 by Molmil
Cytosolic copper storage protein Csp from Streptomyces lividans: Cu loaded form
Descriptor: COPPER (I) ION, Cytosolic copper storage protein
Authors:Straw, M.L, Chaplin, A.K, Hough, M.A, Worrall, J.A.R.
Deposit date:2017-09-25
Release date:2018-08-08
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:A cytosolic copper storage protein provides a second level of copper tolerance in Streptomyces lividans.
Metallomics, 10, 2018
6UUZ
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BU of 6uuz by Molmil
Structure of ACLY in the presence of citrate and CoA
Descriptor: ATP-citrate synthase, COENZYME A
Authors:Xuepeng, W, Ronen, M.
Deposit date:2019-11-01
Release date:2020-01-01
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Molecular basis for acetyl-CoA production by ATP-citrate lyase.
Nat.Struct.Mol.Biol., 27, 2020
5IP0
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BU of 5ip0 by Molmil
PHA Binding Protein PhaP (Phasin)
Descriptor: CADMIUM ION, PHA granule-associated protein
Authors:Chen, G.Q, Wang, X.Q, Zhao, H.Y.
Deposit date:2016-03-09
Release date:2017-01-25
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural Insights on PHA Binding Protein PhaP from Aeromonas hydrophila
Sci Rep, 6, 2016
1S5T
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BU of 1s5t by Molmil
Crystal Structure Analysis of a mutant of DIHYDRODIPICOLINATE SYNTHASE--residue thr44 to val44
Descriptor: Dihydrodipicolinate synthase
Authors:Dobson, R.C.J, Valegard, K, Gerrard, J.A.
Deposit date:2004-01-21
Release date:2004-04-27
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The Crystal Structure of Three Site-directed Mutants of Escherichia coli Dihydrodipicolinate Synthase: Further Evidence for a Catalytic Triad
J.MOL.BIOL., 338, 2004
6MFG
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BU of 6mfg by Molmil
HLA-DQ2-glia-alpha1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, HLA class II histocompatibility antigen, DQ alpha 1 chain, ...
Authors:Petersen, J, Ciacchi, L, Rossjohn, J.
Deposit date:2018-09-10
Release date:2018-11-21
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Discriminative T-cell receptor recognition of highly homologous HLA-DQ2-bound gluten epitopes.
J. Biol. Chem., 294, 2019
6EOY
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BU of 6eoy by Molmil
Transthyretin in complex with 4-(1,3-Benzothiazol-2-yl)-2-methylaniline
Descriptor: 4-(1,3-benzothiazol-2-yl)-2-methyl-aniline, Transthyretin
Authors:Leite, J.P, Gales, L.
Deposit date:2017-10-10
Release date:2021-10-06
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.38 Å)
Cite:Targeting transthyretin in Alzheimer's disease: Drug discovery of small-molecule chaperones as disease-modifying drug candidates for Alzheimer's disease.
Eur.J.Med.Chem., 226, 2021
2JAH
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BU of 2jah by Molmil
Biochemical and structural analysis of the Clavulanic acid dehydeogenase (CAD) from Streptomyces clavuligerus
Descriptor: CLAVULANIC ACID DEHYDROGENASE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:MacKenzie, A.K, Kershaw, N.J, Hernandez, H, Robinson, C.V, Schofield, C.J, Andersson, I.
Deposit date:2006-11-28
Release date:2007-02-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Clavulanic Acid Dehydrogenase: Structural and Biochemical Analysis of the Final Step in the Biosynthesis of the Beta-Lactamase Inhibitor Clavulanic Acid
Biochemistry, 46, 2007
6UV5
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BU of 6uv5 by Molmil
Structure of human ATP citrate lyase in complex with acetyl-CoA and oxaloacetate
Descriptor: ACETYL COENZYME *A, ATP citrate lyase, OXALOACETATE ION
Authors:Wei, X, Marmorstein, R.
Deposit date:2019-11-01
Release date:2019-12-25
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Molecular basis for acetyl-CoA production by ATP-citrate lyase.
Nat.Struct.Mol.Biol., 27, 2020
7ZZI
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BU of 7zzi by Molmil
Plasmodium falciparum hexokinase complexed with glucose and citrate
Descriptor: 1,2-ETHANEDIOL, CITRIC ACID, Phosphotransferase, ...
Authors:Fritz-Wolf, K, Dillenberger, M, Rahlfs, S, Becker, K.
Deposit date:2022-05-25
Release date:2023-08-30
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Analysis of Plasmodium falciparum Hexokinase Provides Novel Information about Catalysis Due to a Plasmodium -Specific Insertion.
Int J Mol Sci, 24, 2023
6PBK
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BU of 6pbk by Molmil
Archaellum periplasmic stator protein complex FlaF and FlaG from Sulfolobus acidocaldarius
Descriptor: 1,2-ETHANEDIOL, Conserved flagellar protein F, DI(HYDROXYETHYL)ETHER, ...
Authors:Tsai, C.-L, Tainer, J.A.
Deposit date:2019-06-14
Release date:2019-11-20
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.805 Å)
Cite:The structure of the periplasmic FlaG-FlaF complex and its essential role for archaellar swimming motility.
Nat Microbiol, 5, 2020
6UUW
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BU of 6uuw by Molmil
Structure of human ATP citrate lyase E599Q mutant in complex with Mg2+, citrate, ATP and CoA
Descriptor: (2S)-2-hydroxy-2-[2-oxo-2-(phosphonooxy)ethyl]butanedioic acid, ADENOSINE-5'-DIPHOSPHATE, ATP-citrate synthase, ...
Authors:Wei, X, Marmorstein, R.
Deposit date:2019-11-01
Release date:2019-12-25
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (2.85 Å)
Cite:Molecular basis for acetyl-CoA production by ATP-citrate lyase
Nat.Struct.Mol.Biol., 27, 2020
8JBD
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BU of 8jbd by Molmil
Crystal structure of Adenylosuccinate lyase from Thermus thermophilus HB8, TtPurB
Descriptor: Adenylosuccinate lyase
Authors:Nemoto, N, Kawai, G, Sampei, G.
Deposit date:2023-05-08
Release date:2023-11-15
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Crystal structure of adenylosuccinate lyase from the thermophilic bacterium Thermus thermophilus HB8.
Acta Crystallogr.,Sect.F, 79, 2023
6PK4
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BU of 6pk4 by Molmil
cryoEM structure of the substrate-bound human CTP synthase 2 filament
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CTP synthase 2, URIDINE 5'-TRIPHOSPHATE
Authors:Lynch, E.M, Kollman, J.M.
Deposit date:2019-06-28
Release date:2019-12-25
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Coupled structural transitions enable highly cooperative regulation of human CTPS2 filaments.
Nat.Struct.Mol.Biol., 27, 2020
8G5C
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BU of 8g5c by Molmil
Structure of ACLY-D1026A-substrates, local refinement of ASH domain
Descriptor: (3S)-citryl-Coenzyme A, ADENOSINE-5'-DIPHOSPHATE, ATP-citrate synthase, ...
Authors:Xuepeng, W, Ronen, M.
Deposit date:2023-02-12
Release date:2023-05-10
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (2.2 Å)
Cite:Allosteric role of the citrate synthase homology domain of ATP citrate lyase.
Nat Commun, 14, 2023
4XNG
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BU of 4xng by Molmil
Central Domain of Mycoplasma Genitalium Terminal Organelle protein MG491
Descriptor: Uncharacterized protein MG218.1
Authors:Martinelli, L, Fita, I.
Deposit date:2015-01-15
Release date:2016-03-30
Last modified:2016-04-27
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure-Guided Mutations in the Terminal Organelle Protein MG491 Cause Major Motility and Morphologic Alterations on Mycoplasma genitalium.
Plos Pathog., 12, 2016
8G5D
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BU of 8g5d by Molmil
Structure of ACLY-D1026A-products, local refinement of ASH domain
Descriptor: (3S)-citryl-Coenzyme A, ACETYL COENZYME *A, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Wei, X, Marmorstein, R.
Deposit date:2023-02-13
Release date:2023-05-10
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Allosteric role of the citrate synthase homology domain of ATP citrate lyase.
Nat Commun, 14, 2023
8J60
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BU of 8j60 by Molmil
Structural and mechanistic insight into ribosomal ITS2 RNA processing by nuclease-kinase machinery
Descriptor: LAS1 protein, Polynucleotide 5'-hydroxyl-kinase GRC3
Authors:Chen, J, Chen, H, Li, S, Lin, X, Hu, R, Zhang, K, Liu, L.
Deposit date:2023-04-24
Release date:2024-01-17
Method:ELECTRON MICROSCOPY (3.39 Å)
Cite:Structural and mechanistic insights into ribosomal ITS2 RNA processing by nuclease-kinase machinery.
Elife, 12, 2024
8J5Y
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BU of 8j5y by Molmil
Structural and mechanistic insight into ribosomal ITS2 RNA processing by nuclease-kinase machinery
Descriptor: LAS1 isoform 1, Polynucleotide 5'-hydroxyl-kinase GRC3
Authors:Chen, J, Chen, H, Li, S, Lin, X, Hu, R, Zhang, K, Liu, L.
Deposit date:2023-04-24
Release date:2024-01-17
Method:ELECTRON MICROSCOPY (3.07 Å)
Cite:Structural and mechanistic insights into ribosomal ITS2 RNA processing by nuclease-kinase machinery.
Elife, 12, 2024
1OVM
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BU of 1ovm by Molmil
Crystal structure of Indolepyruvate decarboxylase from Enterobacter cloacae
Descriptor: Indole-3-pyruvate decarboxylase, MAGNESIUM ION, THIAMINE DIPHOSPHATE
Authors:Schutz, A, Sandalova, T, Ricagno, S, Hubner, G, Konig, S, Schneider, G.
Deposit date:2003-03-27
Release date:2003-06-03
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Crystal structure of thiamindiphosphate-dependent indolepyruvate decarboxylase from Enterobacter cloacae, an enzyme involved in the biosynthesis of the plant hormone indole-3-acetic acid
Eur.J.Biochem., 270, 2003
8AE6
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BU of 8ae6 by Molmil
Cryo-EM structure of the SEA complex wing (SEACIT)
Descriptor: Maintenance of telomere capping protein 5, Nitrogen permease regulator 2, Nitrogen permease regulator 3, ...
Authors:Tafur, L, Loewith, R.
Deposit date:2022-07-12
Release date:2022-11-02
Last modified:2023-05-10
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Cryo-EM structure of the SEA complex.
Nature, 611, 2022
8JQ9
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BU of 8jq9 by Molmil
Novel Anti-phage System
Descriptor: Endonuclease GajA
Authors:Li, J, Wang, Z, Wang, L.
Deposit date:2023-06-13
Release date:2024-02-28
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (2.66 Å)
Cite:Structures and activation mechanism of the Gabija anti-phage system.
Nature, 629, 2024
6F9I
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BU of 6f9i by Molmil
Crystal structure of KLC2 bound to the second tryptophan-acidic motif peptide from calsyntenin-1
Descriptor: Calsyntenin-1, Kinesin light chain 2
Authors:Cockburn, J.J.B.
Deposit date:2017-12-14
Release date:2018-09-05
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.993 Å)
Cite:Insights into Kinesin-1 Activation from the Crystal Structure of KLC2 Bound to JIP3.
Structure, 26, 2018
6N1G
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BU of 6n1g by Molmil
Crystal structure of Aquaglyceroporin AQP7
Descriptor: Aquaporin-7, GLYCEROL
Authors:Vahedi-Faridi, A, Lodowski, D, Kowatz, T.
Deposit date:2018-11-08
Release date:2019-11-13
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.995 Å)
Cite:Aquaporin-7: A Dynamic Aquaglyceroporin With Greater Water and Glycerol Permeability Than Its Bacterial Homolog GlpF.
Front Physiol, 11, 2020
5J83
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BU of 5j83 by Molmil
Crystal structure of L-arabinonate dehydratase in apo-form
Descriptor: Dihydroxyacid dehydratase/phosphogluconate dehydratase
Authors:Rahman, M.M, Rouvinen, J, Hakulinen, N.
Deposit date:2016-04-07
Release date:2017-06-21
Last modified:2018-01-10
Method:X-RAY DIFFRACTION (3.001 Å)
Cite:The Crystal Structure of a Bacterial l-Arabinonate Dehydratase Contains a [2Fe-2S] Cluster.
ACS Chem. Biol., 12, 2017

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數據於2024-07-17公開中

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