6PK4

cryoEM structure of the substrate-bound human CTP synthase 2 filament

Summary for 6PK4

Entry DOI	10.2210/pdb6pk4/pdb
EMDB information	20354
Descriptor	CTP synthase 2, URIDINE 5'-TRIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE (3 entities in total)
Functional Keywords	enzyme, filament, protein fibril
Biological source	Homo sapiens (Human)
Total number of polymer chains	4
Total formula weight	267003.01
Authors	Lynch, E.M.,Kollman, J.M. (deposition date: 2019-06-28, release date: 2019-12-25, Last modification date: 2024-03-20)
Primary citation	Lynch, E.M.,Kollman, J.M. Coupled structural transitions enable highly cooperative regulation of human CTPS2 filaments. Nat.Struct.Mol.Biol., 27:42-48, 2020 Cited by PubMed: 31873303 DOI: 10.1038/s41594-019-0352-5 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.5 Å)

Structure validation