8HAJ
 
 | | Cryo-EM structure of the p300 catalytic core bound to the H4K12acK16ac nucleosome, class 2 (4.8 angstrom resolution) | | Descriptor: | DNA (180-mer), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | | Authors: | Kikuchi, M, Morita, S, Wakamori, M, Shin, S, Uchikubo-Kamo, T, Shirouzu, M, Umehara, T. | | Deposit date: | 2022-10-26 | | Release date: | 2023-05-17 | | Last modified: | 2023-07-26 | | Method: | ELECTRON MICROSCOPY (4.8 Å) | | Cite: | Epigenetic mechanisms to propagate histone acetylation by p300/CBP.
Nat Commun, 14, 2023
|
|
8HAK
 | | Cryo-EM structure of the p300 catalytic core bound to the H4K12acK16ac nucleosome, class 4 (4.5 angstrom resolution) | | Descriptor: | DNA (180-mer), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | | Authors: | Kikuchi, M, Morita, S, Wakamori, M, Shin, S, Uchikubo-Kamo, T, Shirouzu, M, Umehara, T. | | Deposit date: | 2022-10-26 | | Release date: | 2023-05-17 | | Last modified: | 2023-07-26 | | Method: | ELECTRON MICROSCOPY (4.5 Å) | | Cite: | Epigenetic mechanisms to propagate histone acetylation by p300/CBP.
Nat Commun, 14, 2023
|
|
8HKI
 | | Human TRiC open state | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, T-complex protein 1 subunit alpha, T-complex protein 1 subunit beta, ... | | Authors: | Cong, Y, Liu, C.X. | | Deposit date: | 2022-11-27 | | Release date: | 2023-12-13 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Pathway and mechanism of tubulin folding mediated by TRiC/CCT conjugated with its ATPase cycle revealed by cryo-EM
To Be Published
|
|
8RVE
 | | Vimentin intermediate filament | | Descriptor: | Vimentin | | Authors: | Eibauer, M, Medalia, O. | | Deposit date: | 2024-02-01 | | Release date: | 2024-04-10 | | Last modified: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (7.2 Å) | | Cite: | Vimentin filaments integrate low-complexity domains in a complex helical structure.
Nat.Struct.Mol.Biol., 31, 2024
|
|
8RZV
 | |
1IFR
 | |
1IVT
 | | NMR structures of the C-terminal globular domain of human lamin A/C | | Descriptor: | Lamin A/C | | Authors: | Krimm, I, Ostlund, C, Gilquin, B, Couprie, J, Hossenlopp, P, Mornon, J.P, Bonn, G, Courvalin, J.C, Worman, H.J, Zinn-Justin, S. | | Deposit date: | 2002-03-29 | | Release date: | 2002-08-21 | | Last modified: | 2023-12-27 | | Method: | SOLUTION NMR | | Cite: | The Ig-like structure of the C-terminal domain of lamin A/C, mutated in muscular dystrophies, cardiomyopathy, and partial lipodystrophy.
Structure, 10, 2002
|
|
1IO4
 | |
8RG0
 | | Structure of human eIF3 core from closed 48S translation initiation complex | | Descriptor: | 18S rRNA, 40S ribosomal protein S13, 40S ribosomal protein S14, ... | | Authors: | Petrychenko, V, Yi, S.-H, Liedtke, D, Peng, B.Z, Rodnina, M.V, Fischer, N. | | Deposit date: | 2023-12-13 | | Release date: | 2024-08-14 | | Last modified: | 2024-10-02 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structural basis for translational control by the human 48S initiation complex.
Nat.Struct.Mol.Biol., 2024
|
|
8RO2
 | | Integrative Structure of the human intron lariat Spliceosome (ILS'') | | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, ATP-dependent RNA helicase DHX15, CWF19-like protein 1, ... | | Authors: | Rothe, P, Vorlaender, M.K, Plaschka, C. | | Deposit date: | 2024-01-11 | | Release date: | 2024-09-18 | | Last modified: | 2024-10-16 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Mechanism for the initiation of spliceosome disassembly.
Nature, 632, 2024
|
|
1JEY
 | | Crystal Structure of the Ku heterodimer bound to DNA | | Descriptor: | DNA (34-MER), DNA (5'-D(*GP*TP*TP*TP*TP*TP*AP*GP*TP*TP*TP*AP*TP*TP*GP*GP*GP*CP*GP*CP*G)-3'), Ku70, ... | | Authors: | Walker, J.R, Corpina, R.A, Goldberg, J. | | Deposit date: | 2001-06-19 | | Release date: | 2001-08-10 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structure of the Ku heterodimer bound to DNA and its implications for double-strand break repair.
Nature, 412, 2001
|
|
8H6K
 | | Cryo-EM structure of human exon-defined spliceosome in the mature B state. | | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... | | Authors: | Zhang, W, Zhan, X, Zhang, X, Bai, R, Lei, J, Yan, C, Shi, Y. | | Deposit date: | 2022-10-18 | | Release date: | 2024-05-01 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Structural insights into human exon-defined spliceosome prior to activation.
Cell Res., 34, 2024
|
|
8H6E
 | | Cryo-EM structure of human exon-defined spliceosome in the late pre-B state. | | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... | | Authors: | Zhang, W, Zhan, X, Zhang, X, Bai, R, Lei, J, Yan, C, Shi, Y. | | Deposit date: | 2022-10-17 | | Release date: | 2024-05-01 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structural insights into human exon-defined spliceosome prior to activation.
Cell Res., 34, 2024
|
|
8H6J
 | | Cryo-EM structure of human exon-defined spliceosome in the mature pre-B state. | | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... | | Authors: | Zhang, W, Zhan, X, Zhang, X, Lei, J, Yan, C, Shi, Y. | | Deposit date: | 2022-10-18 | | Release date: | 2024-05-01 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (3.25 Å) | | Cite: | Structural insights into human exon-defined spliceosome prior to activation.
Cell Res., 34, 2024
|
|
8H6L
 | | Cryo-EM structure of human exon-defined spliceosome in the early B state. | | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... | | Authors: | Zhang, W, Zhan, X, Zhang, X, Bai, R, Lei, J, Yan, C, Shi, Y. | | Deposit date: | 2022-10-18 | | Release date: | 2024-05-01 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (2.6 Å) | | Cite: | Structural insights into human exon-defined spliceosome prior to activation.
Cell Res., 34, 2024
|
|
6AHD
 | | The Cryo-EM Structure of Human Pre-catalytic Spliceosome (B complex) at 3.8 angstrom resolution | | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, Brr2, U5 small nuclear ribonucleoprotein 200 kDa helicase, ... | | Authors: | Zhan, X, Yan, C, Zhang, X, Shi, Y. | | Deposit date: | 2018-08-17 | | Release date: | 2018-11-14 | | Last modified: | 2021-06-30 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Structures of the human pre-catalytic spliceosome and its precursor spliceosome.
Cell Res., 28, 2018
|
|
2KQS
 | |
7R5K
 | | Human nuclear pore complex (constricted) | | Descriptor: | Aladin, E3 SUMO-protein ligase RanBP2, Nuclear pore complex protein Nup107, ... | | Authors: | Mosalaganti, S, Obarska-Kosinska, A, Siggel, M, Taniguchi, R, Turonova, B, Zimmerli, C.E, Buczak, K, Schmidt, F.H, Margiotta, E, Mackmull, M.T, Hagen, W.J.H, Hummer, G, Kosinski, J, Beck, M. | | Deposit date: | 2022-02-10 | | Release date: | 2022-06-22 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (12 Å) | | Cite: | AI-based structure prediction empowers integrative structural analysis of human nuclear pores.
Science, 376, 2022
|
|
6H3A
 | | Crystal structure of the KAP1 RBCC domain in complex with the SMARCAD1 CUE1 domain. | | Descriptor: | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1, Transcription intermediary factor 1-beta, ZINC ION | | Authors: | Newman, J.A, Aitkenhead, H, Lim, M, Williams, H.L, Svejstrup, J.Q, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. | | Deposit date: | 2018-07-17 | | Release date: | 2019-06-26 | | Last modified: | 2024-05-15 | | Method: | X-RAY DIFFRACTION (5.505 Å) | | Cite: | A Ubiquitin-Binding Domain that Binds a Structural Fold Distinct from that of Ubiquitin.
Structure, 27, 2019
|
|
7R5J
 | | Human nuclear pore complex (dilated) | | Descriptor: | Aladin, E3 SUMO-protein ligase RanBP2, Nuclear pore complex protein Nup107, ... | | Authors: | Mosalaganti, S, Obarska-Kosinska, A, Siggel, M, Taniguchi, R, Turonova, B, Zimmerli, C.E, Buczak, K, Schmidt, F.H, Margiotta, E, Mackmull, M.T, Hagen, W.J.H, Hummer, G, Kosinski, J, Beck, M. | | Deposit date: | 2022-02-10 | | Release date: | 2022-09-21 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (50 Å) | | Cite: | AI-based structure prediction empowers integrative structural analysis of human nuclear pores
Science, 376, 2022
|
|
8I0U
 | | The cryo-EM structure of human Bact-IV complex | | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, Cell division cycle 5-like protein, Crooked neck-like protein 1, ... | | Authors: | Zhan, X, Lu, Y, Shi, Y. | | Deposit date: | 2023-01-11 | | Release date: | 2024-07-31 | | Last modified: | 2024-08-07 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Molecular basis for the activation of human spliceosome.
Nat Commun, 15, 2024
|
|
8Y0W
 | | dormant ribosome with eIF5A, eEF2 and SERBP1 | | Descriptor: | 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... | | Authors: | Du, M, Zeng, F. | | Deposit date: | 2024-01-23 | | Release date: | 2024-02-07 | | Last modified: | 2024-08-21 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Implication of Stm1 in the protection of eIF5A, eEF2 and tRNA through dormant ribosomes.
Front Mol Biosci, 11, 2024
|
|
6FF4
 | | human Bact spliceosome core structure | | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ... | | Authors: | Haselbach, D, Komarov, I, Agafonov, D, Hartmuth, K, Graf, B, Kastner, B, Luehrmann, R, Stark, H. | | Deposit date: | 2018-01-03 | | Release date: | 2018-08-29 | | Last modified: | 2020-10-07 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structure and Conformational Dynamics of the Human Spliceosomal BactComplex.
Cell, 172, 2018
|
|
7ZNK
 | | Structure of an endogenous human TREX complex bound to mRNA | | Descriptor: | RNA, Spliceosome RNA helicase DDX39B, THO complex subunit 1, ... | | Authors: | Pacheco-Fiallos, F.B, Vorlaender, M.K, Plaschka, C. | | Deposit date: | 2022-04-21 | | Release date: | 2023-05-03 | | Last modified: | 2024-07-24 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | mRNA recognition and packaging by the human transcription-export complex.
Nature, 616, 2023
|
|
7ZNL
 | | Structure of the human TREX core THO-UAP56 complex | | Descriptor: | Spliceosome RNA helicase DDX39B, THO complex subunit 1, THO complex subunit 2, ... | | Authors: | Pacheco-Fiallos, F.B, Vorlaender, M.K, Plaschka, C. | | Deposit date: | 2022-04-21 | | Release date: | 2023-05-17 | | Last modified: | 2024-07-24 | | Method: | ELECTRON MICROSCOPY (3.45 Å) | | Cite: | mRNA recognition and packaging by the human transcription-export complex.
Nature, 616, 2023
|
|
