8RG0

Structure of human eIF3 core from closed 48S translation initiation complex

Summary for 8RG0

• Entry DOI: 10.2210/pdb8rg0/pdb
• Related: 8PJ1 8PJ2 8PJ3 8PJ4 8PJ5 8PJ6
• EMDB information: 19128
• Descriptor: Eukaryotic translation initiation factor 3 subunit K, 40S ribosomal protein S17, 40S ribosomal protein SA, ... (21 entities in total)
• Functional Keywords: ribosome, translation, initiation, 48s, eif, human, eukaryotic, factor, codon, scanning, open, reading
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 19
• Total formula weight: 1428922.97

Authors

Petrychenko, V.,Yi, S.-H.,Liedtke, D.,Peng, B.Z.,Rodnina, M.V.,Fischer, N. (deposition date: 2023-12-13, release date: 2024-08-14)

• Primary citation: Petrychenko, V.,Yi, S.-H.,Liedtke, D.,Peng, B.Z.,Rodnina, M.V.,Fischer, N.; Structural basis for translational control by the human 48S initiation complex from codon scanning toward subunit joining; Nat.Struct.Mol.Biol., 2024; DOI: 10.1038/s41594-024-01378-4

Experimental method

ELECTRON MICROSCOPY (3.4 Å)