2HFK
| Pikromycin thioesterase in complex with product 10-deoxymethynolide | Descriptor: | (3R,4S,5S,7R,9E,11R,12R)-12-ETHYL-4-HYDROXY-3,5,7,11-TETRAMETHYLOXACYCLODODEC-9-ENE-2,8-DIONE, DIMETHYL SULFOXIDE, MAGNESIUM ION, ... | Authors: | Akey, D.L, Kittendorf, J.D, Giraldes, J.W, Fecik, R.A, Sherman, D.H, Smith, J.L. | Deposit date: | 2006-06-24 | Release date: | 2006-09-19 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Structural Basis for Macrolactonization by the Pikromycin Thioesterase NAT.CHEM.BIOL., 2, 2006
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2GPU
| Estrogen Related Receptor-gamma ligand binding domain complexed with 4-hydroxy-tamoxifen | Descriptor: | 4-HYDROXYTAMOXIFEN, Estrogen-related receptor gamma | Authors: | Wang, L, Zuercher, W.J, Consler, T.G, Lambert, M.H, Miller, A.B, Osband-Miller, L.A, McKee, D.D, Willson, T.M, Nolte, R.T. | Deposit date: | 2006-04-18 | Release date: | 2006-09-26 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | X-ray crystal structures of the estrogen-related receptor-gamma ligand binding domain in three functional states reveal the molecular basis of small molecule regulation. J.Biol.Chem., 281, 2006
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2GWM
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2GN6
| Crystal structure of UDP-GlcNAc inverting 4,6-dehydratase in complex with NADP and UDP-GlcNAc | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, UDP-GlcNAc C6 dehydratase, ... | Authors: | Ishiyama, N, Creuzenet, C, Lam, J.S, Berghuis, A.M. | Deposit date: | 2006-04-09 | Release date: | 2006-05-09 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural Studies of FlaA1 from Helicobacter pylori Reveal the Mechanism for Inverting 4,6-Dehydratase Activity. J.Biol.Chem., 281, 2006
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2GNN
| Crystal Structure of the Orf Virus NZ2 Variant of VEGF-E | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, BENZAMIDINE, ... | Authors: | Prota, A.E, Pieren, M, Wagner, A, Kostrewa, D, Winkler, F.K, Ballmer-Hofer, K. | Deposit date: | 2006-04-10 | Release date: | 2006-05-09 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of the Orf virus NZ2 variant of vascular endothelial growth factor-E. Implications for receptor specificity. J.Biol.Chem., 281, 2006
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2GO7
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2GPO
| Estrogen Related Receptor-gamma ligand binding domain complexed with a synthetic peptide from RIP140 | Descriptor: | Estrogen-related receptor gamma, Nuclear receptor-interacting protein 1 | Authors: | Wang, L, Zuercher, W.J, Consler, T.G, Lambert, M.H, Miller, A.B, Osband-miller, L.A, McKee, D.D, Willson, T.M, Nolte, R.T. | Deposit date: | 2006-04-18 | Release date: | 2006-09-26 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | X-ray crystal structures of the estrogen-related receptor-gamma ligand binding domain in three functional states reveal the molecular basis of small molecule regulation. J.Biol.Chem., 281, 2006
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2GQR
| SAICAR Synthetase Complexed with ADP-Mg2+ | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Phosphoribosylaminoimidazole-succinocarboxamide synthase | Authors: | Ginder, N.D, Honzatko, R.B. | Deposit date: | 2006-04-21 | Release date: | 2006-05-16 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Nucleotide Complexes of Escherichia coli Phosphoribosylaminoimidazole Succinocarboxamide Synthetase. J.Biol.Chem., 281, 2006
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2ETH
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2ESM
| Crystal Structure of ROCK 1 bound to fasudil | Descriptor: | 5-(1,4-DIAZEPAN-1-SULFONYL)ISOQUINOLINE, Rho-associated protein kinase 1 | Authors: | Jacobs, M. | Deposit date: | 2005-10-26 | Release date: | 2005-11-08 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | The Structure of Dimeric ROCK I Reveals the Mechanism for Ligand Selectivity. J.Biol.Chem., 281, 2006
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2EVH
| Structure of a Ndt80-DNA complex (MSE mutant mA7G) | Descriptor: | 5'-D(*AP*GP*TP*TP*TP*CP*TP*GP*TP*GP*TP*CP*GP*C)-3', 5'-D(*TP*GP*CP*GP*AP*CP*AP*CP*AP*GP*AP*AP*AP*C)-3', NDT80 protein | Authors: | Lamoureux, J.S, Glover, J.N. | Deposit date: | 2005-10-31 | Release date: | 2006-03-21 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.989 Å) | Cite: | Principles of Protein-DNA Recognition Revealed in the Structural Analysis of Ndt80-MSE DNA Complexes. Structure, 14, 2006
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2FJ2
| Crystal Structure of Viral Macrophage Inflammatory Protein-II | Descriptor: | Viral macrophage inflammatory protein-II | Authors: | Li, Y, Liu, D, Cao, R, Kumar, S, Dong, C.Z, wilson, S.R, Gao, Y.G, Huang, Z. | Deposit date: | 2005-12-30 | Release date: | 2006-12-26 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of chemically synthesized vMIP-II. Proteins, 67, 2007
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2EVD
| Crystal structure of human Glycolipid Transfer Protein complexed with 12:0 Lactosylceramide | Descriptor: | DECANE, Glycolipid transfer protein, LAURIC ACID, ... | Authors: | Malinina, L, Malakhova, M.L, Kanack, A.T, Abagyan, R, Brown, R.E, Patel, D.J. | Deposit date: | 2005-10-31 | Release date: | 2006-11-14 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The liganding of glycolipid transfer protein is controlled by glycolipid acyl structure. Plos Biol., 4, 2006
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2EVL
| Crystal structure of human Glycolipid Transfer Protein complexed with 18:2 Galactosylceramide | Descriptor: | Glycolipid transfer protein, LINOLEIC ACID, N-OCTANE, ... | Authors: | Malinina, L, Malakhova, M.L, Kanack, A.T, Abagyan, R, Brown, R.E, Patel, D.J. | Deposit date: | 2005-10-31 | Release date: | 2006-11-14 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The liganding of glycolipid transfer protein is controlled by glycolipid acyl structure. Plos Biol., 4, 2006
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2ETK
| Crystal Structure of ROCK 1 bound to hydroxyfasudil | Descriptor: | 1-(1-HYDROXY-5-ISOQUINOLINESULFONYL)HOMOPIPERAZINE, Rho-associated protein kinase 1 | Authors: | Jacobs, M. | Deposit date: | 2005-10-27 | Release date: | 2005-11-08 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.96 Å) | Cite: | The Structure of Dimeric ROCK I Reveals the Mechanism for Ligand Selectivity. J.Biol.Chem., 281, 2006
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2EWR
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2EXC
| Inhibitor complex of JNK3 | Descriptor: | Mitogen-activated protein kinase 10, N-{2'-[(4-FLUOROPHENYL)AMINO]-4,4'-BIPYRIDIN-2-YL}-4-METHOXYCYCLOHEXANECARBOXAMIDE | Authors: | Xue, Y. | Deposit date: | 2005-11-08 | Release date: | 2006-11-14 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Inhibitor complex of JNK3 To be Published
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2EUZ
| Structure of a Ndt80-DNA complex (MSE mutant mC5T) | Descriptor: | 5'-D(*AP*GP*TP*TP*TP*TP*TP*AP*TP*GP*TP*CP*GP*C)-3', 5'-D(*TP*GP*CP*GP*AP*CP*AP*TP*AP*AP*AP*AP*AP*C)-3', NDT80 protein | Authors: | Lamoureux, J.S, Glover, J.N. | Deposit date: | 2005-10-30 | Release date: | 2006-03-21 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.56 Å) | Cite: | Principles of Protein-DNA Recognition Revealed in the Structural Analysis of Ndt80-MSE DNA Complexes. Structure, 14, 2006
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2EXI
| Structure of the family43 beta-Xylosidase D15G mutant from geobacillus stearothermophilus | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GLYCEROL, ... | Authors: | Brux, C, Niefind, K, Shallom-Shezifi, D, Shoham, Y, Schomburg, D. | Deposit date: | 2005-11-08 | Release date: | 2006-04-04 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | The Structure of an Inverting GH43 beta-Xylosidase from Geobacillus stearothermophilus with its Substrate Reveals the Role of the Three Catalytic Residues. J.Mol.Biol., 359, 2006
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2D09
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7XVX
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2GE7
| Structure of the C-terminal dimerization domain of infectious bronchitis virus nucleocapsid protein | Descriptor: | Nucleocapsid protein | Authors: | Jayaram, H, Fan, H, Bowman, B.R, Ooi, A, Jayaram, J, Collisson, E.W, Lescar, J, Prasad, B.V. | Deposit date: | 2006-03-18 | Release date: | 2006-06-27 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | X-ray structures of the N- and C-terminal domains of a coronavirus nucleocapsid protein: implications for nucleocapsid formation. J.Virol., 80, 2006
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2GIQ
| Hepatitis C virus RNA-dependent RNA polymerase NS5B with NNI-2 inhibitor | Descriptor: | 1-(2-CYCLOPROPYLETHYL)-3-(1,1-DIOXIDO-2H-1,2,4-BENZOTHIADIAZIN-3-YL)-6-FLUORO-4-HYDROXYQUINOLIN-2(1H)-ONE, RNA-directed RNA polymerase | Authors: | Harris, S.F. | Deposit date: | 2006-03-29 | Release date: | 2007-04-03 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Selection and characterization of replicon variants dually resistant to thumb- and palm-binding nonnucleoside polymerase inhibitors of the hepatitis C virus. J.Virol., 80, 2006
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2GHA
| Thermotoga maritima maltotriose binding protein bound with maltotriose | Descriptor: | alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, maltose ABC transporter, periplasmic maltose-binding protein | Authors: | Cuneo, M.J, Changela, A, Hocker, B, Beese, L.S, Hellinga, H.W. | Deposit date: | 2006-03-27 | Release date: | 2007-02-06 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | T. maritima maltotriose binding protein To be Published
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2GLZ
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