2GPU

Estrogen Related Receptor-gamma ligand binding domain complexed with 4-hydroxy-tamoxifen

Summary for 2GPU

Entry DOI	10.2210/pdb2gpu/pdb
Related	2GP7 2GPO 2GPP 2GPV
Descriptor	Estrogen-related receptor gamma, 4-HYDROXYTAMOXIFEN (3 entities in total)
Functional Keywords	estrogen related receptor, err, errg, esrrg, nuclear receptor, steroid receptor, transcription
Biological source	Homo sapiens (human)
Cellular location	Nucleus : P62508
Total number of polymer chains	1
Total formula weight	26471.89
Authors	Wang, L.,Zuercher, W.J.,Consler, T.G.,Lambert, M.H.,Miller, A.B.,Osband-Miller, L.A.,McKee, D.D.,Willson, T.M.,Nolte, R.T. (deposition date: 2006-04-18, release date: 2006-09-26, Last modification date: 2023-08-30)
Primary citation	Wang, L.,Zuercher, W.J.,Consler, T.G.,Lambert, M.H.,Miller, A.B.,Orband-Miller, L.A.,McKee, D.D.,Willson, T.M.,Nolte, R.T. X-ray crystal structures of the estrogen-related receptor-gamma ligand binding domain in three functional states reveal the molecular basis of small molecule regulation. J.Biol.Chem., 281:37773-37781, 2006 Cited by PubMed: 16990259 DOI: 10.1074/jbc.M608410200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation