3PDM
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![BU of 3pdm by Molmil](/molmil-images/mine/3pdm) | Hibiscus Latent Singapore virus | Descriptor: | Coat protein, RNA (5'-R(P*GP*AP*A)-3') | Authors: | Tewary, S.K, Wong, S.M, Swaminathan, K. | Deposit date: | 2010-10-22 | Release date: | 2011-01-12 | Last modified: | 2024-03-20 | Method: | FIBER DIFFRACTION (3.5 Å) | Cite: | Structure of Hibiscus latent Singapore virus by fiber diffraction: A non-conserved His122 contributes to coat protein stability J.Mol.Biol., 2010
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4II4
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3PDR
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![BU of 3pdr by Molmil](/molmil-images/mine/3pdr) | Crystal structure of manganese bound M-box RNA | Descriptor: | M-box Riboswitch RNA, MANGANESE (II) ION, POTASSIUM ION | Authors: | Ramesh, A, Winkler, W.C. | Deposit date: | 2010-10-23 | Release date: | 2011-02-23 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.853 Å) | Cite: | Insights into Metalloregulation by M-box Riboswitch RNAs via Structural Analysis of Manganese-Bound Complexes. J.Mol.Biol., 407, 2011
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1XAW
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4S0R
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![BU of 4s0r by Molmil](/molmil-images/mine/4s0r) | Structure of GS-TnrA complex | Descriptor: | GLUTAMINE, Glutamine synthetase, MAGNESIUM ION, ... | Authors: | Schumacher, M.A, Chinnam, N.G, Cuthbert, B, Tonthat, N.K. | Deposit date: | 2015-01-04 | Release date: | 2015-03-04 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Structures of regulatory machinery reveal novel molecular mechanisms controlling B. subtilis nitrogen homeostasis. Genes Dev., 29, 2015
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4IK1
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![BU of 4ik1 by Molmil](/molmil-images/mine/4ik1) | High resolution structure of GCaMPJ at pH 8.5 | Descriptor: | CALCIUM ION, RCaMP, Green fluorescent protein | Authors: | Chen, Y, Song, X, Miao, L, Zhu, Y, Ji, G. | Deposit date: | 2012-12-25 | Release date: | 2014-02-05 | Last modified: | 2017-06-21 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural insight into enhanced calcium indicator GCaMP3 and GCaMPJ to promote further improvement. Protein Cell, 4, 2013
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1XJU
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![BU of 1xju by Molmil](/molmil-images/mine/1xju) | |
3PDH
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4IHF
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![BU of 4ihf by Molmil](/molmil-images/mine/4ihf) | Chasing Acyl Carrier Protein Through a Catalytic Cycle of Lipid A Production | Descriptor: | Acyl carrier protein, CHLORIDE ION, S-[2-({N-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] (3R)-3-hydroxytetradecanethioate, ... | Authors: | Masoudi, A, Raetz, C.R.H, Pemble, C.W. | Deposit date: | 2012-12-18 | Release date: | 2013-11-13 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Chasing acyl carrier protein through a catalytic cycle of lipid A production. Nature, 505, 2014
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4RLV
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4IK4
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![BU of 4ik4 by Molmil](/molmil-images/mine/4ik4) | High resolution structure of GCaMP3 at pH 5.0 | Descriptor: | CALCIUM ION, RCaMP, Green fluorescent protein | Authors: | Chen, Y, Song, X, Miao, L, Zhu, Y, Ji, G. | Deposit date: | 2012-12-25 | Release date: | 2014-02-05 | Last modified: | 2017-06-21 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Structural insight into enhanced calcium indicator GCaMP3 and GCaMPJ to promote further improvement. Protein Cell, 4, 2013
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1ZV1
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![BU of 1zv1 by Molmil](/molmil-images/mine/1zv1) | Crystal structure of the dimerization domain of doublesex protein from D. melanogaster | Descriptor: | Doublesex protein | Authors: | Weiss, M.A, Bayrer, J.R, Wan, Z, Li, B, Phillips, N.B. | Deposit date: | 2005-06-01 | Release date: | 2005-08-09 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Dimerization of doublesex is mediated by a cryptic ubiquitin-associated domain fold: implications for sex-specific gene regulation J.Biol.Chem., 280, 2005
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4ROD
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![BU of 4rod by Molmil](/molmil-images/mine/4rod) | Human TFIIB-related factor 2 (Brf2) and TBP bound to TRNAU1 promoter | Descriptor: | Non-template strand, TATA-box-binding protein, Template strand, ... | Authors: | Vannini, A, Gouge, J, Satia, K, Guthertz, N. | Deposit date: | 2014-10-28 | Release date: | 2015-12-30 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Redox Signaling by the RNA Polymerase III TFIIB-Related Factor Brf2. Cell(Cambridge,Mass.), 163, 2015
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1ZRQ
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![BU of 1zrq by Molmil](/molmil-images/mine/1zrq) | Escherichia coli Methylenetetrahydrofolate Reductase (reduced) complexed with NADH, pH 6.0 | Descriptor: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 5,10-methylenetetrahydrofolate reductase, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Pejchal, R, Sargeant, R, Ludwig, M.L. | Deposit date: | 2005-05-19 | Release date: | 2005-08-09 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structures of NADH and CH(3)-H(4)Folate Complexes of Escherichia coli Methylenetetrahydrofolate Reductase Reveal a Spartan Strategy for a Ping-Pong Reaction Biochemistry, 44, 2005
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1ZSD
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![BU of 1zsd by Molmil](/molmil-images/mine/1zsd) | Crystal Structure Of HLA-B*3501 Presenting an 11-Mer EBV Antigen EPLPQGQLTAY | Descriptor: | BZLF1 trans-activator protein, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | Authors: | Miles, J.J, Elhassen, D, Borg, N.A, Silins, S.L, Tynan, F.E, Burrows, J.M, Purcell, A.W, Kjer-Nielsen, L, Rossjohn, J, Burrows, S.R, McCluskey, J. | Deposit date: | 2005-05-24 | Release date: | 2005-06-07 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | CTL Recognition of a Bulged Viral Peptide Involves Biased TCR Selection. J.Immunol., 175, 2005
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3PF4
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![BU of 3pf4 by Molmil](/molmil-images/mine/3pf4) | Crystal structure of Bs-CspB in complex with r(GUCUUUA) | Descriptor: | Cold shock protein cspB, MAGNESIUM ION, SODIUM ION, ... | Authors: | Sachs, R, Max, K.E.A, Heinemann, U. | Deposit date: | 2010-10-27 | Release date: | 2011-09-21 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.38 Å) | Cite: | RNA single strands bind to a conserved surface of the major cold shock protein in crystals and solution. Rna, 18, 2012
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4RSN
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![BU of 4rsn by Molmil](/molmil-images/mine/4rsn) | Crystal structure of the E267V mutant of cytochrome P450 BM3 | Descriptor: | Bifunctional P-450/NADPH-P450 reductase, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Zhou, W.H, Zhang, A.L, Zhang, T, Ren, X.K, Yorke, J.A, Taylor, A, Wong, L.-L. | Deposit date: | 2014-11-09 | Release date: | 2015-12-02 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.701 Å) | Cite: | Expanding the drug metabolism function of P450BM3 To be Published
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1ZVD
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![BU of 1zvd by Molmil](/molmil-images/mine/1zvd) | Regulation of Smurf2 Ubiquitin Ligase Activity by Anchoring the E2 to the HECT domain | Descriptor: | PHOSPHATE ION, SODIUM ION, Smad ubiquitination regulatory factor 2 | Authors: | Ogunjimi, A.A, Briant, D.J, Pece-Barbara, N, Le Roy, C, Di Guglielmo, G.M, Kavsak, P, Rasmussen, R.K, Seet, B.T, Sicheri, F, Wrana, J.L. | Deposit date: | 2005-06-01 | Release date: | 2005-08-09 | Last modified: | 2011-09-28 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Regulation of Smurf2 Ubiquitin Ligase Activity by Anchoring the E2 to the HECT Domain. Mol.Cell, 19, 2005
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5PNY
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![BU of 5pny by Molmil](/molmil-images/mine/5pny) | PanDDA analysis group deposition -- Crystal Structure of BRD1 in complex with N10174a | Descriptor: | 1,2-ETHANEDIOL, 5-amino-1-(2-chlorophenyl)-1H-pyrazole-4-carbonitrile, Bromodomain-containing protein 1, ... | Authors: | Pearce, N.M, Krojer, T, Talon, R, Bradley, A.R, Fairhead, M, Sethi, R, Wright, N, MacLean, E, Collins, P, Brandao-Neto, J, Douangamath, A, Renjie, Z, Dias, A, Ng, J, Brennan, P.E, Cox, O, Bountra, C, Arrowsmith, C.H, Edwards, A, von Delft, F. | Deposit date: | 2017-02-07 | Release date: | 2017-03-15 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.479 Å) | Cite: | A multi-crystal method for extracting obscured crystallographic states from conventionally uninterpretable electron density. Nat Commun, 8, 2017
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5POF
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![BU of 5pof by Molmil](/molmil-images/mine/5pof) | PanDDA analysis group deposition -- Crystal Structure of BRD1 in complex with N10941a | Descriptor: | 1,2-ETHANEDIOL, Bromodomain-containing protein 1, N-(1-benzylpiperidin-4-yl)acetamide, ... | Authors: | Pearce, N.M, Krojer, T, Talon, R, Bradley, A.R, Fairhead, M, Sethi, R, Wright, N, MacLean, E, Collins, P, Brandao-Neto, J, Douangamath, A, Renjie, Z, Dias, A, Ng, J, Brennan, P.E, Cox, O, Bountra, C, Arrowsmith, C.H, Edwards, A, von Delft, F. | Deposit date: | 2017-02-07 | Release date: | 2017-03-15 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.27 Å) | Cite: | A multi-crystal method for extracting obscured crystallographic states from conventionally uninterpretable electron density. Nat Commun, 8, 2017
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4I24
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![BU of 4i24 by Molmil](/molmil-images/mine/4i24) | Structure of T790M EGFR kinase domain co-crystallized with dacomitinib | Descriptor: | (2E)-N-{4-[(3-chloro-4-fluorophenyl)amino]-7-methoxyquinazolin-6-yl}-4-(piperidin-1-yl)but-2-enamide, Epidermal growth factor receptor | Authors: | Gajiwala, K.S, Feng, J, Ferre, R, Ryan, K, Brodsky, O, Stewart, A. | Deposit date: | 2012-11-21 | Release date: | 2013-01-16 | Last modified: | 2013-02-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Insights into the Aberrant Activity of Mutant EGFR Kinase Domain and Drug Recognition. Structure, 21, 2013
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3KX5
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![BU of 3kx5 by Molmil](/molmil-images/mine/3kx5) | Crystal structure of Bacillus megaterium BM3 heme domain mutant F261E | Descriptor: | Bifunctional P-450/NADPH-P450 reductase, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION | Authors: | Girvan, H.M, Levy, C.W, Leys, D, Munro, A.W. | Deposit date: | 2009-12-02 | Release date: | 2010-05-19 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.686 Å) | Cite: | Glutamate-haem ester bond formation is disfavoured in flavocytochrome P450 BM3: characterization of glutamate substitution mutants at the haem site of P450 BM3. Biochem.J., 427, 2010
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4QLV
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![BU of 4qlv by Molmil](/molmil-images/mine/4qlv) | yCP in complex with tripeptidic epoxyketone inhibitor 17 | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, MAGNESIUM ION, N-(morpholin-4-ylacetyl)-D-alanyl-N-[(2S,4R)-5-hydroxy-4-methyl-3-oxo-1-phenylpentan-2-yl]-O-methyl-L-tyrosinamide, ... | Authors: | de Bruin, G, Huber, E, Xin, B, van Rooden, E, Al-Ayed, K, Kim, K, Kisselev, A, Driessen, C, van der Marel, G, Groll, M, Overkleeft, H. | Deposit date: | 2014-06-13 | Release date: | 2014-07-23 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structure-based design of beta 1i or beta 5i specific inhibitors of human immunoproteasomes J.Med.Chem., 57, 2014
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3KN1
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![BU of 3kn1 by Molmil](/molmil-images/mine/3kn1) | Crystal Structure of Golgi Phosphoprotein 3 N-term Truncation Variant | Descriptor: | Golgi phosphoprotein 3, SULFATE ION | Authors: | Schmitz, K.R, Bessman, N.J, Setty, T.G, Ferguson, K.M. | Deposit date: | 2009-11-11 | Release date: | 2009-12-15 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | PtdIns4P recognition by Vps74/GOLPH3 links PtdIns 4-kinase signaling to retrograde Golgi trafficking. J.Cell Biol., 187, 2009
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3N8N
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![BU of 3n8n by Molmil](/molmil-images/mine/3n8n) | Crystal structure of 3-dehydroquinate dehydratase from Mycobacterium tuberculosis in complex with inhibitor 6 | Descriptor: | (1R,4R,5R)-3-(tert-butylcarbamoyl)-1,4,5-trihydroxycyclohex-2-ene-1-carboxylic acid, 3-dehydroquinate dehydratase | Authors: | Dias, M.V.B, Snee, W.C, Bromfield, K.M, Payne, R, Palaninathan, S.K, Ciulli, A, Howard, N.I, Abell, C, Sacchettini, J.C, Blundell, T.L. | Deposit date: | 2010-05-28 | Release date: | 2011-05-11 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural investigation of inhibitor designs targeting 3-dehydroquinate dehydratase from the shikimate pathway of Mycobacterium tuberculosis. Biochem.J., 436, 2011
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