1ZVD
Regulation of Smurf2 Ubiquitin Ligase Activity by Anchoring the E2 to the HECT domain
Summary for 1ZVD
Entry DOI | 10.2210/pdb1zvd/pdb |
Descriptor | Smad ubiquitination regulatory factor 2, SODIUM ION, PHOSPHATE ION, ... (4 entities in total) |
Functional Keywords | ubiquitin ligasecatalytic mechanism, x-ray crystal structure, tgfbeta, ligase |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: Q9HAU4 |
Total number of polymer chains | 1 |
Total formula weight | 44953.13 |
Authors | Ogunjimi, A.A.,Briant, D.J.,Pece-Barbara, N.,Le Roy, C.,Di Guglielmo, G.M.,Kavsak, P.,Rasmussen, R.K.,Seet, B.T.,Sicheri, F.,Wrana, J.L. (deposition date: 2005-06-01, release date: 2005-08-09, Last modification date: 2011-09-28) |
Primary citation | Ogunjimi, A.A.,Briant, D.J.,Pece-Barbara, N.,Le Roy, C.,Di Guglielmo, G.M.,Kavsak, P.,Rasmussen, R.K.,Seet, B.T.,Sicheri, F.,Wrana, J.L. Regulation of Smurf2 Ubiquitin Ligase Activity by Anchoring the E2 to the HECT Domain. Mol.Cell, 19:297-308, 2005 Cited by PubMed: 16061177DOI: 10.1016/j.molcel.2005.06.028 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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