6NCA
| HLA-A2 (A*02:01) bound to a peptide from the Epstein-Barr virus BRLF1 protein | Descriptor: | Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ... | Authors: | Stern, L.J, Selin, L.K, Song, I.Y. | Deposit date: | 2018-12-11 | Release date: | 2019-10-23 | Last modified: | 2020-01-29 | Method: | X-RAY DIFFRACTION (3.300001 Å) | Cite: | CDR3 alpha drives selection of the immunodominant Epstein Barr virus (EBV) BRLF1-specific CD8 T cell receptor repertoire in primary infection. Plos Pathog., 15, 2019
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6NHA
| Crystal structure of SYNT001, a human FcRn blocking monoclonal antibody | Descriptor: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Beta-2-microglobulin, IgG receptor FcRn large subunit p51, ... | Authors: | Blumberg, R.S, Cheung, J, Mahmood, A, Gandhi, A.K. | Deposit date: | 2018-12-21 | Release date: | 2019-12-25 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.381 Å) | Cite: | Blocking FcRn in humans reduces circulating IgG levels and inhibits IgG immune complex-mediated immune responses. Sci Adv, 5, 2019
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7RM4
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5HYJ
| 1E6 TCR in Complex with HLA-A02 carrying AQWGPDPAAA | Descriptor: | ALA-GLN-TRP-GLY-PRO-ASP-PRO-ALA-ALA-ALA, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | Authors: | Rizkallah, P.J, Bulek, A.M, Cole, D.K, Sewell, A.K. | Deposit date: | 2016-02-01 | Release date: | 2016-05-04 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.06 Å) | Cite: | A "hotspot" for autoimmune T cells in type 1 diabetes. J.Clin.Invest., 126, 2016
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5U98
| The crystal structure of a self-peptide complexed to Abacavir and HLA-B*57:01 | Descriptor: | Beta-2-microglobulin, HLA class I histocompatibility antigen, B-57 alpha chain, ... | Authors: | Ostrov, D.A, Bracey, A.W, Pompeu, Y.A, Jakoncic, J, Buus, S, Buus, A.S, Schutte, R.J. | Deposit date: | 2016-12-15 | Release date: | 2017-07-19 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural Elements Recognized by Abacavir-Induced T Cells. Int J Mol Sci, 18, 2017
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5TXS
| Crystal structure of an anaplastic lymphoma kinase-derived neuroblastoma tumor antigen bound to the Human Major Histocompatibility Complex Class I molecule HLA-B*1501 | Descriptor: | Beta-2-microglobulin, HLA class I histocompatibility antigen, B-15 alpha chain, ... | Authors: | Toor, J, Rao, A.A, Salama, S, Tripathi, S, Haussler, D, Sgourakis, N.G. | Deposit date: | 2016-11-17 | Release date: | 2017-11-29 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.697 Å) | Cite: | A Recurrent Mutation in Anaplastic Lymphoma Kinase with Distinct Neoepitope Conformations. Front Immunol, 9, 2018
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5U1R
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1YDP
| 1.9A crystal structure of HLA-G | Descriptor: | Beta-2-microglobulin, CHLORIDE ION, COBALT (II) ION, ... | Authors: | Clements, C.S, Kjer-nielsen, L, Kostenko, L, Hoare, H.L, Dunstone, M.A, Moses, E, Freed, K, Brooks, A.G, Rossjohn, J, Mccluskey, J. | Deposit date: | 2004-12-25 | Release date: | 2005-03-08 | Last modified: | 2021-11-10 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of HLA-G: A nonclassical MHC class I molecule expressed at the fetal-maternal interface PROC.NATL.ACAD.SCI.USA, 102, 2005
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6MTM
| Crystal Structure of EM2 TCR in complex with HLA-B*37:01-NP338 | Descriptor: | Beta-2-microglobulin, EM2 TCR alpha chain, EM2 TCR beta chain, ... | Authors: | Gras, S. | Deposit date: | 2018-10-19 | Release date: | 2019-02-13 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Broad CD8+T cell cross-recognition of distinct influenza A strains in humans. Nat Commun, 9, 2018
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6M1B
| A new V27M variant of beta 2 microglobulin induced amyloidosis in a patient with long-term hemodialysis | Descriptor: | Beta-2-microglobulin, CALCIUM ION, GLYCEROL, ... | Authors: | So, M, Nakahara, S, Nakaniwa, T, Tanaka, H, Kurisu, G, Goto, Y. | Deposit date: | 2020-02-25 | Release date: | 2021-01-06 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | Dialysis-related amyloidosis associated with a novel beta 2 -microglobulin variant. Amyloid, 28, 2021
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1ZHK
| Crystal structure of HLA-B*3501 presenting 13-mer EBV antigen LPEPLPQGQLTAY | Descriptor: | Beta-2-microglobulin, EBV-peptide LPEPLPQGQLTAY, HLA class I histocompatibility antigen, ... | Authors: | Tynan, F.E, Borg, N.A, Miles, J.J, Beddoe, T, El-Hassen, D, Silins, S.L, van Zuylen, W.J, Purcell, A.W, Kjer-Nielsen, L, McCluskey, J, Burrows, S.R, Rossjohn, J. | Deposit date: | 2005-04-26 | Release date: | 2005-05-17 | Last modified: | 2014-04-16 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | The high resolution structures of highly bulged viral epitopes bound to the major histocompatability class I: Implications for T-cell receptor engagement and T-cell immunodominance J.Biol.Chem., 280, 2005
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1XH3
| Conformational Restraints and Flexibility of 14-Meric Peptides in Complex with HLA-B*3501 | Descriptor: | Beta-2-microglobulin, HLA class I histocompatibility antigen, B-35 alpha chain, ... | Authors: | Probst-Kepper, M, Hecht, H.J, Herrmann, H, Janke, V, Ocklenburg, F, Klempnauer, J, van den Eynde, B.J, Weiss, S. | Deposit date: | 2004-09-17 | Release date: | 2004-11-23 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.48 Å) | Cite: | Conformational restraints and flexibility of 14-meric peptides in complex with HLA-B*3501. J.Immunol., 173, 2004
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1XR9
| Crystal Structures of HLA-B*1501 in Complex with Peptides from Human UbcH6 and Epstein-Barr Virus EBNA-3 | Descriptor: | Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ... | Authors: | Roder, G, Blicher, T, Johannessen, B.R, Kristensen, O, Buus, S, Gajhede, M. | Deposit date: | 2004-10-14 | Release date: | 2005-04-14 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.788 Å) | Cite: | Crystal structures of two peptide-HLA-B*1501 complexes; structural characterization of the HLA-B62 supertype Acta Crystallogr.,Sect.D, 62, 2006
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6NPR
| Crystal structure of H-2Dd with C84-C139 disulfide in complex with gp120 derived peptide P18-I10 | Descriptor: | ARG-GLY-PRO-GLY-ARG-ALA-PHE-VAL-THR-ILE, Beta-2-microglobulin, H-2 class I histocompatibility antigen, ... | Authors: | Toor, J, McShan, A.C, Tripathi, S.M, Sgourakis, N.G. | Deposit date: | 2019-01-18 | Release date: | 2020-01-22 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.37 Å) | Cite: | Molecular determinants of chaperone interactions on MHC-I for folding and antigen repertoire selection. Proc.Natl.Acad.Sci.USA, 116, 2019
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7RRG
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6MT6
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5JZI
| Crystal structure of 1406 TCR bound to HLA-A2 with HCV 1406-1415 antigen peptide | Descriptor: | Beta-2-microglobulin, HCV1406 TCR alpha chain, HCV1406 TCR beta chain, ... | Authors: | Wang, Y, Piepenbrink, K.H, Baker, B.M. | Deposit date: | 2016-05-16 | Release date: | 2017-05-31 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | How an alloreactive T-cell receptor achieves peptide and MHC specificity. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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7U21
| Human Class I MHC HLA-A2 in complex with AVGSYVYSV peptide | Descriptor: | Beta-2-microglobulin, MHC class I antigen, A-2 alpha chain, ... | Authors: | Weiss, L.I, Baker, B.M. | Deposit date: | 2022-02-22 | Release date: | 2022-06-01 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Physicochemical Heuristics for Identifying High Fidelity, Near-Native Structural Models of Peptide/MHC Complexes. Front Immunol, 13, 2022
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7TUD
| Crystal structure of HLA-B*44:05 (T73C) with 6mer EEFGRC and dipeptide GL | Descriptor: | 1,2-ETHANEDIOL, Beta-2-microglobulin, EEFGRC peptide, ... | Authors: | Jiang, J, Natarajan, K, Kim, E, Boyd, L.F, Margulies, D.H. | Deposit date: | 2022-02-02 | Release date: | 2022-09-07 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Structural mechanism of tapasin-mediated MHC-I peptide loading in antigen presentation. Nat Commun, 13, 2022
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7TUE
| Crystal structure of Tapasin in complex with HLA-B*44:05 (T73C) | Descriptor: | Beta-2-microglobulin, HLA class I histocompatibility antigen, B alpha chain, ... | Authors: | Jiang, J, Natarajan, K, Kim, E, Boyd, L.F, Margulies, D.H. | Deposit date: | 2022-02-02 | Release date: | 2022-09-07 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structural mechanism of tapasin-mediated MHC-I peptide loading in antigen presentation. Nat Commun, 13, 2022
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7TUC
| Crystal structure of HLA-B*44:05 (T73C) with 9mer EEFGRAFSF | Descriptor: | 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ... | Authors: | Jiang, J, Natarajan, K, Kim, E, Boyd, L.F, Margulies, D.H. | Deposit date: | 2022-02-02 | Release date: | 2022-09-07 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | Structural mechanism of tapasin-mediated MHC-I peptide loading in antigen presentation. Nat Commun, 13, 2022
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6NUX
| CD1a-lipid binary complex | Descriptor: | (2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-ol, 1,2-ETHANEDIOL, Beta-2-microglobulin, ... | Authors: | Wegrecki, M, Le Nours, J, Rossjohn, J. | Deposit date: | 2019-02-03 | Release date: | 2020-01-15 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Human T cell response to CD1a and contact dermatitis allergens in botanical extracts and commercial skin care products. Sci Immunol, 5, 2020
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1ZVS
| Crystal structure of the first class MHC mamu and Tat-Tl8 complex | Descriptor: | Beta-2-microglobulin, MHC class I antigen, Tat-Tl8 | Authors: | Lou, Z, Chu, F, Gao, G.F, Rao, Z. | Deposit date: | 2005-06-02 | Release date: | 2006-06-13 | Last modified: | 2019-11-06 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | First glimpse of the peptide presentation by rhesus macaque MHC class I: crystal structures of Mamu-A*01 complexed with two immunogenic SIV epitopes and insights into CTL escape. J Immunol., 178, 2007
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1ZT4
| The crystal structure of human CD1d with and without alpha-Galactosylceramide | Descriptor: | Beta-2-microglobulin, N-{(1S,2R,3S)-1-[(ALPHA-D-GALACTOPYRANOSYLOXY)METHYL]-2,3-DIHYDROXYHEPTADECYL}HEXACOSANAMIDE, T-cell surface glycoprotein CD1d | Authors: | Koch, M, Stronge, V.S, Shepherd, D, Gadola, S.D, Mathew, B, Ritter, G, Fersht, A.R, Besra, G.S, Schmidt, R.R, Jones, E.Y, Cerundolo, V, Structural Proteomics in Europe (SPINE) | Deposit date: | 2005-05-26 | Release date: | 2005-07-19 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The crystal structure of human CD1d with and without alpha-galactosylceramide Nat.Immunol., 6, 2005
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5V5M
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