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5TXD
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BU of 5txd by Molmil
Structure of amyloid-beta derived peptide - NKGAIF
Descriptor: Amyloid beta A4 protein, PHOSPHATE ION
Authors:Sangwan, S, Sawaya, M.R, Eisenberg, D.
Deposit date:2016-11-16
Release date:2017-11-15
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.452 Å)
Cite:Distal amyloid beta-protein fragments template amyloid assembly.
Protein Sci., 27, 2018
5TXH
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BU of 5txh by Molmil
Polymorphic form 2 of amyloid-beta derived peptide - IFAEDV
Descriptor: IFAEDV, ISOPROPYL ALCOHOL
Authors:Sangwan, S, Sawaya, M.R, Eisenberg, D.
Deposit date:2016-11-16
Release date:2017-11-15
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Distal amyloid beta-protein fragments template amyloid assembly.
Protein Sci., 27, 2018
6C7T
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BU of 6c7t by Molmil
Directed evolutionary changes in Kemp Eliminase KE07 - Crystal 20 round 5
Descriptor: Kemp Eliminase KE07
Authors:Jackson, C.J, Hong, N.-S, Carr, P.D.
Deposit date:2018-01-23
Release date:2018-08-01
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:The evolution of multiple active site configurations in a designed enzyme.
Nat Commun, 9, 2018
6CAI
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BU of 6cai by Molmil
Directed evolutionary changes in Kemp Eliminase KE07 - Crystal 24 round 7
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Kemp Eliminase KE07
Authors:Jackson, C.J, Hong, N.-S, Carr, P.D.
Deposit date:2018-01-30
Release date:2018-08-01
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:The evolution of multiple active site configurations in a designed enzyme.
Nat Commun, 9, 2018
6C8B
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BU of 6c8b by Molmil
Directed evolutionary changes in Kemp Eliminase KE07 - Crystal 23 round 6
Descriptor: Kemp eliminase KE07
Authors:Jackson, C.J, Hong, N.-S, Carr, P.D.
Deposit date:2018-01-24
Release date:2018-08-01
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:The evolution of multiple active site configurations in a designed enzyme.
Nat Commun, 9, 2018
6C7H
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BU of 6c7h by Molmil
Directed evolutionary changes in Kemp Eliminase KE07 - Crystal 18 Design Trp50Ala mutant
Descriptor: Kemp eliminase KE07
Authors:Jackson, C.J, Hong, N.-S, Carr, P.D.
Deposit date:2018-01-22
Release date:2018-08-01
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:The evolution of multiple active site configurations in a designed enzyme.
Nat Commun, 9, 2018
6C7M
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BU of 6c7m by Molmil
Directed evolutionary changes in Kemp Eliminase KE07 - Crystal 19 round 5
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, Kemp Eliminase KE07
Authors:Jackson, C.J, Hong, N.-S, Carr, P.D.
Deposit date:2018-01-22
Release date:2018-08-01
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:The evolution of multiple active site configurations in a designed enzyme.
Nat Commun, 9, 2018
6C7V
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BU of 6c7v by Molmil
Directed evolutionary changes in Kemp Eliminase KE07 - Crystal 22 round 5
Descriptor: Kemp eliminase KE07
Authors:Jackson, C.J, Hong, N.-S, Carr, P.D.
Deposit date:2018-01-23
Release date:2018-08-01
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:The evolution of multiple active site configurations in a designed enzyme.
Nat Commun, 9, 2018
5UN6
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BU of 5un6 by Molmil
Frizzled-8 complex with designed surrogate Wnt agonist, A1 dataset
Descriptor: Designed Wnt agonist B12, Frizzled-8
Authors:Janda, C.Y, Garcia, K.C, Jude, K.M.
Deposit date:2017-01-30
Release date:2017-05-03
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Surrogate Wnt agonists that phenocopy canonical Wnt and beta-catenin signalling.
Nature, 545, 2017
5UN5
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BU of 5un5 by Molmil
Frizzled-8 complex with designed surrogate Wnt agonist, crystal form 1
Descriptor: Designed Wnt agonist B12, Frizzled-8
Authors:Janda, C.Y, Garcia, K.C.
Deposit date:2017-01-30
Release date:2017-05-03
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.994 Å)
Cite:Surrogate Wnt agonists that phenocopy canonical Wnt and beta-catenin signalling.
Nature, 545, 2017
7OMM
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BU of 7omm by Molmil
Cryo-EM structure of N. gonorhoeae LptDE in complex with ProMacrobodies (MBPs have not been built de novo)
Descriptor: LPS-assembly lipoprotein LptE, LPS-assembly protein LptD, ProMacrobody 21,Maltodextrin-binding protein, ...
Authors:Botte, M, Ni, D, Schenck, S, Zimmermann, I, Chami, M, Bocquet, N, Egloff, P, Bucher, D, Trabuco, M, Cheng, R.K.Y, Brunner, J.D, Seeger, M.A, Stahlberg, H, Hennig, M.
Deposit date:2021-05-24
Release date:2022-05-04
Last modified:2022-05-11
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Cryo-EM structures of a LptDE transporter in complex with Pro-macrobodies offer insight into lipopolysaccharide translocation.
Nat Commun, 13, 2022
7P19
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BU of 7p19 by Molmil
Crystal structure of SARS-CoV-2 RBD Q498Y complexed with human ACE2
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
Authors:Erausquin, E, Lopez-Sagaseta, J.
Deposit date:2021-07-01
Release date:2022-07-13
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.24 Å)
Cite:Structural bases for the higher adherence to ACE2 conferred by the SARS-CoV-2 spike Q498Y substitution.
Acta Crystallogr D Struct Biol, 78, 2022
7A4Y
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BU of 7a4y by Molmil
Crystal structure of the P5P6 coiled-coil in complex with nanobody Nb34.
Descriptor: 1,2-ETHANEDIOL, Coiled-coil P5 peptide, Coiled-coil P6 peptide, ...
Authors:Hadzi, S.
Deposit date:2020-08-20
Release date:2021-05-05
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.157 Å)
Cite:A nanobody toolbox targeting dimeric coiled-coil modules for functionalization of designed protein origami structures.
Proc.Natl.Acad.Sci.USA, 118, 2021
7A4T
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BU of 7a4t by Molmil
Crystal structure of the GCN coiled-coil in complex with nanobody Nb39
Descriptor: 1,2-ETHANEDIOL, ACETYL GROUP, GCN4 isoform 1, ...
Authors:Hadzi, S.
Deposit date:2020-08-20
Release date:2021-05-05
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.124 Å)
Cite:A nanobody toolbox targeting dimeric coiled-coil modules for functionalization of designed protein origami structures.
Proc.Natl.Acad.Sci.USA, 118, 2021
7A50
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BU of 7a50 by Molmil
Crystal structure of the APH coiled-coil in complex with nanobody Nb26
Descriptor: 1,2-ETHANEDIOL, Coiled-coil APH, Nanobody Nb26
Authors:Hadzi, S.
Deposit date:2020-08-20
Release date:2021-05-05
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.999 Å)
Cite:A nanobody toolbox targeting dimeric coiled-coil modules for functionalization of designed protein origami structures.
Proc.Natl.Acad.Sci.USA, 118, 2021
7A4D
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BU of 7a4d by Molmil
Crystal structure of the APH coiled-coil in complex with nanobodies Nb28 and Nb30
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, APH coiled-coil, ...
Authors:Hadzi, S.
Deposit date:2020-08-19
Release date:2021-05-05
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.694 Å)
Cite:A nanobody toolbox targeting dimeric coiled-coil modules for functionalization of designed protein origami structures.
Proc.Natl.Acad.Sci.USA, 118, 2021
7A48
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BU of 7a48 by Molmil
Crystal structure of the APH coiled-coil in complex with Nb49
Descriptor: APH colied-coil, Nanobody 49
Authors:Hadzi, S.
Deposit date:2020-08-19
Release date:2021-05-05
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.547 Å)
Cite:A nanobody toolbox targeting dimeric coiled-coil modules for functionalization of designed protein origami structures.
Proc.Natl.Acad.Sci.USA, 118, 2021
7MCC
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BU of 7mcc by Molmil
Crystal structure of an AI-designed TIM-barrel F2C
Descriptor: AI-designed TIM-barrel F2C, SULFATE ION
Authors:Mathews, I.I, Anand-Achim, N, Perez, C.P, Huang, P.S.
Deposit date:2021-04-02
Release date:2022-01-19
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.46 Å)
Cite:Protein sequence design with a learned potential.
Nat Commun, 13, 2022
7MCD
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BU of 7mcd by Molmil
Crystal structure of an AI-designed TIM-barrel F15C
Descriptor: AI-designed TIM-barrel F15C
Authors:Mathews, I.I, Anand-Achim, N, Perez, C.P, Huang, P.
Deposit date:2021-04-02
Release date:2022-01-19
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Protein sequence design with a learned potential.
Nat Commun, 13, 2022
6V67
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BU of 6v67 by Molmil
Apo Structure of the De Novo PD-1 Binding Miniprotein GR918.2
Descriptor: PD-1 Binding Miniprotein GR918.2
Authors:Bick, M.J, Bryan, C.M, Baker, D, Dimaio, F, Kang, A.
Deposit date:2019-12-04
Release date:2020-12-09
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.07 Å)
Cite:Computational design of a synthetic PD-1 agonist.
Proc.Natl.Acad.Sci.USA, 118, 2021
5NJG
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BU of 5njg by Molmil
Structure of an ABC transporter: part of the structure that could be built de novo
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5D3-Fab heavy chain, 5D3-Fab light chain, ...
Authors:Taylor, N.M.I, Manolaridis, I, Jackson, S.M, Kowal, J, Stahlberg, H, Locher, K.P.
Deposit date:2017-03-28
Release date:2017-06-07
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.78 Å)
Cite:Structure of the human multidrug transporter ABCG2.
Nature, 546, 2017
1CH8
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BU of 1ch8 by Molmil
STRUCTURE OF ADENYLOSUCCINATE SYNTHETASE FROM E. COLI COMPLEXED WITH A STRINGENT EFFECTOR, PPG2':3'P
Descriptor: GUANOSINE 5'-DIPHOSPHATE 2':3'-CYCLIC MONOPHOSPHATE, HADACIDIN, INOSINIC ACID, ...
Authors:Hou, Z, Cashel, M, Fromm, H.J, Honzatko, R.B.
Deposit date:1999-03-31
Release date:1999-12-29
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Effectors of the stringent response target the active site of Escherichia coli adenylosuccinate synthetase.
J.Biol.Chem., 274, 1999
1DJ2
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BU of 1dj2 by Molmil
STRUCTURES OF ADENYLOSUCCINATE SYNTHETASE FROM TRITICUM AESTIVUM AND ARABIDOPSIS THALIANA
Descriptor: ADENYLOSUCCINATE SYNTHETASE, GUANOSINE-5'-DIPHOSPHATE
Authors:Prade, L, Cowan-Jacob, S.W, Chemla, P, Potter, S, Ward, E, Fonne-Pfister, R.
Deposit date:1999-12-01
Release date:2000-03-24
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structures of adenylosuccinate synthetase from Triticum aestivum and Arabidopsis thaliana.
J.Mol.Biol., 296, 2000
1CIB
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BU of 1cib by Molmil
STRUCTURE OF ADENYLOSUCCINATE SYNTHETASE FROM E. COLI COMPLEXED WITH GDP, IMP, HADACIDIN, AND NO3
Descriptor: ADENYLOSUCCINATE SYNTHETASE, GUANOSINE-5'-DIPHOSPHATE, HADACIDIN, ...
Authors:Hou, Z, Cashel, M, Fromm, H.J, Honzatko, R.B.
Deposit date:1999-03-31
Release date:2000-04-05
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Effectors of the stringent response target the active site of Escherichia coli adenylosuccinate synthetase.
J.Biol.Chem., 274, 1999
1DY3
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BU of 1dy3 by Molmil
Ternary complex of 7,8-dihydro-6-hydroxymethylpterinpyrophosphokinase from Escherichia coli with ATP and a substrate analogue.
Descriptor: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, 7,8-DIHYDRO-6-HYDROXYMETHYL-7-METHYL-7-[2-PHENYLETHYL]-PTERIN, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Stammers, D.K, Achari, A, Somers, D.O, Bryant, P.K, Rosemond, J, Scott, D.L, Champness, J.N.
Deposit date:2000-01-21
Release date:2000-08-18
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:2.0A X-Ray Structure of the Ternary Complex of 7,8-Dihydro-6-Hydroxymethylpterinpyrophosphokinase from Escherichia Coli with ATP and a Substrate Analogue
FEBS Lett., 456, 1999

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數據於2024-07-24公開中

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