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4X0Y
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BU of 4x0y by Molmil
JC polyomavirus VP1 from a genotype 3 strain
Descriptor: 1,2-ETHANEDIOL, GLYCEROL, Major capsid protein, ...
Authors:Stroh, L.J, Stehle, T.
Deposit date:2014-11-24
Release date:2015-04-22
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The Greater Affinity of JC Polyomavirus Capsid for alpha 2,6-Linked Lactoseries Tetrasaccharide c than for Other Sialylated Glycans Is a Major Determinant of Infectivity.
J.Virol., 89, 2015
4X15
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BU of 4x15 by Molmil
JC Mad-1 polyomavirus VP1 in complex with GM2 oligosaccharide
Descriptor: 1,2-ETHANEDIOL, GLYCEROL, Major capsid protein VP1, ...
Authors:Stroh, L.J, Stehle, T.
Deposit date:2014-11-24
Release date:2015-04-22
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:The Greater Affinity of JC Polyomavirus Capsid for alpha 2,6-Linked Lactoseries Tetrasaccharide c than for Other Sialylated Glycans Is a Major Determinant of Infectivity.
J.Virol., 89, 2015
4Y5I
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BU of 4y5i by Molmil
Crystal structure of C-terminal modified Tau peptide-hybrid 126B with 14-3-3sigma
Descriptor: 14-3-3 protein sigma, CHLORIDE ION, Microtubule-associated protein tau
Authors:Leysen, S, Bartel, M, Milroy, L, Brunsveld, L, Ottmann, C.
Deposit date:2015-02-11
Release date:2016-01-13
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Stabilizer-Guided Inhibition of Protein-Protein Interactions.
Angew.Chem.Int.Ed.Engl., 54, 2015
4HCZ
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BU of 4hcz by Molmil
PHF1 Tudor in complex with H3K36me3
Descriptor: H3L-like histone, PHD finger protein 1
Authors:Musselman, C.A, Roy, S, Nunez, J, Kutateladze, T.G.
Deposit date:2012-10-01
Release date:2012-11-14
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Molecular basis for H3K36me3 recognition by the Tudor domain of PHF1.
Nat.Struct.Mol.Biol., 19, 2012
3GRG
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BU of 3grg by Molmil
Crystal structure of the F87M/L110M mutant of human transthyretin at pH 7.5
Descriptor: ACETATE ION, GLYCEROL, Transthyretin, ...
Authors:Palmieri, L.C, Freire, J.B.B, Foguel, D, Lima, L.M.T.R.
Deposit date:2009-03-25
Release date:2010-04-07
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Novel Zn2+-binding sites in human transthyretin: implications for amyloidogenesis and retinol-binding protein recognition.
J.Biol.Chem., 285, 2010
4Z2Z
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BU of 4z2z by Molmil
New crystal structure of yeast Ddi1 aspartyl protease reveals substrate engagement mode
Descriptor: DNA damage-inducible protein 1
Authors:Trempe, J.-F, Feng, X, Gehring, K.
Deposit date:2015-03-30
Release date:2016-04-13
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural studies of the yeast DNA damage-inducible protein Ddi1 reveal domain architecture of this eukaryotic protein family.
Sci Rep, 6, 2016
4Z86
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BU of 4z86 by Molmil
Crystal structure of Peptidyl-tRNA hydrolase mutant -N118D from Vibrio cholerae at 1.63A resolution.
Descriptor: Peptidyl-tRNA hydrolase
Authors:Shahid, S, Kabra, A, Pal, R.K, Arora, A.
Deposit date:2015-04-08
Release date:2016-06-08
Last modified:2017-04-05
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Unraveling the stereochemical and dynamic aspects of the catalytic site of bacterial peptidyl-tRNA hydrolase.
RNA, 23, 2017
4Z89
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BU of 4z89 by Molmil
SH3-II of Drosophila Rim-binding protein bound to a Cacophony derived peptide
Descriptor: CALCIUM ION, RIM-binding protein, isoform F, ...
Authors:Driller, J.H, Holton, N, Siebert, M, Boehme, M.A, Wahl, M.C, Sigrist, S.J, Loll, B.
Deposit date:2015-04-08
Release date:2015-08-05
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:A high affinity RIM-binding protein/Aplip1 interaction prevents the formation of ectopic axonal active zones.
Elife, 4, 2015
4JCG
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BU of 4jcg by Molmil
Recombinant wild type Nitrosomonas europaea cytochrome c552
Descriptor: Cytochrome c-552, HEME C
Authors:Wedekind, J.E, Can, M, Krucinska, J, Bren, K.L.
Deposit date:2013-02-21
Release date:2013-08-14
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Structural Characterization of Nitrosomonas europaea Cytochrome c-552 Variants with Marked Differences in Electronic Structure.
Chembiochem, 14, 2013
4XOK
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BU of 4xok by Molmil
Observing the overall rocking motion of a protein in a crystal.
Descriptor: Ubiquitin, ZINC ION
Authors:Coquelle, N, Ma, P, Schanda, P, Colletier, J.P.
Deposit date:2015-01-16
Release date:2015-10-14
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Observing the overall rocking motion of a protein in a crystal.
Nat Commun, 6, 2015
4KQQ
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BU of 4kqq by Molmil
CRYSTAL STRUCTURE OF PENICILLIN-BINDING PROTEIN 3 FROM PSEUDOMONAS AERUGINOSA IN COMPLEX WITH (5S)-Penicilloic Acid
Descriptor: (2S,4S)-2-[(R)-carboxy{[(2R)-2-{[(4-ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino}-2-phenylacetyl]amino}methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, CHLORIDE ION, GLYCEROL, ...
Authors:Nettleship, J.E, Stuart, D.I, Owens, R.J, Ren, J.
Deposit date:2013-05-15
Release date:2013-11-06
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Binding of (5S)-Penicilloic Acid to Penicillin Binding Protein 3.
Acs Chem.Biol., 8, 2013
4ZH1
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BU of 4zh1 by Molmil
Complement factor H in complex with the GM1 glycan
Descriptor: Complement C3, Complement factor H, GLYCEROL, ...
Authors:Blaum, B.S, Stehle, T.
Deposit date:2015-04-24
Release date:2016-01-13
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:Complement Factor H and Simian Virus 40 bind the GM1 ganglioside in distinct conformations.
Glycobiology, 26, 2016
4YXS
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BU of 4yxs by Molmil
CAMP-DEPENDENT PROTEIN KINASE PKA CATALYTIC SUBUNIT WITH PKI-5-24
Descriptor: N-BENZYL-9H-PURIN-6-AMINE, cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha
Authors:Schiffer, A, Wendt, K.U.
Deposit date:2015-03-23
Release date:2015-05-20
Last modified:2015-06-03
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:A combination of spin diffusion methods for the determination of protein-ligand complex structural ensembles.
Angew.Chem.Int.Ed.Engl., 54, 2015
4YXR
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BU of 4yxr by Molmil
CRYSTAL STRUCTURE OF PKA IN COMPLEX WITH inhibitor.
Descriptor: 3-methyl-2H-indazole, cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha
Authors:Schiffer, A, Wendt, K.U.
Deposit date:2015-03-23
Release date:2015-05-27
Last modified:2015-06-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:A combination of spin diffusion methods for the determination of protein-ligand complex structural ensembles.
Angew.Chem.Int.Ed.Engl., 54, 2015
4Z8E
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BU of 4z8e by Molmil
TEAD DBD mutant -deltaL1
Descriptor: Transcriptional enhancer factor TEF-1
Authors:Lee, D.-S, Albarado, D.C, Vonrhein, C, Raman, C.S, Veeraraghavan, S.
Deposit date:2015-04-08
Release date:2016-04-13
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.092 Å)
Cite:A Potential Structural Switch for Regulating DNA-Binding by TEAD Transcription Factors.
J.Mol.Biol., 428, 2016
3GRB
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BU of 3grb by Molmil
Crystal structure of the F87M/L110M mutant of human transthyretin at pH 6.5
Descriptor: ACETATE ION, GLYCEROL, Transthyretin, ...
Authors:Palmieri, L.C, Freire, J.B.B, Foguel, D, Lima, L.M.T.R.
Deposit date:2009-03-25
Release date:2010-04-07
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Novel Zn2+-binding sites in human transthyretin: implications for amyloidogenesis and retinol-binding protein recognition.
J.Biol.Chem., 285, 2010
4ZL7
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BU of 4zl7 by Molmil
Crystal structure of Pseudomonas aeruginosa DsbA E82I: Crystal I
Descriptor: HEXAETHYLENE GLYCOL, Thiol:disulfide interchange protein DsbA
Authors:McMahon, R.M, Martin, J.L.
Deposit date:2015-05-01
Release date:2015-12-09
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.922 Å)
Cite:Sent packing: protein engineering generates a new crystal form of Pseudomonas aeruginosa DsbA1 with increased catalytic surface accessibility.
Acta Crystallogr. D Biol. Crystallogr., 71, 2015
4Z49
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BU of 4z49 by Molmil
Homo Sapiens Fatty Acid Synthetase, Thioesterase Domain at 1.7 Angstroms Resolution
Descriptor: Fatty acid synthase, POTASSIUM ION
Authors:Spraggon, G.
Deposit date:2015-04-01
Release date:2016-03-16
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Estimation of Hydrogen-Exchange Protection Factors from MD Simulation Based on Amide Hydrogen Bonding Analysis.
J.Chem.Inf.Model., 55, 2015
4Z88
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BU of 4z88 by Molmil
SH3-II of Drosophila Rim-binding protein with Aplip1 peptide
Descriptor: JNK-interacting protein 1, PHOSPHATE ION, RIM-binding protein, ...
Authors:Driller, J.H, Holton, N, Siebert, M, Boehme, M.A, Wahl, M.C, Sigrist, S.J, Loll, B.
Deposit date:2015-04-08
Release date:2015-08-05
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:A high affinity RIM-binding protein/Aplip1 interaction prevents the formation of ectopic axonal active zones.
Elife, 4, 2015
4Z9Q
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BU of 4z9q by Molmil
Crystal structure of OXA-58 with disordered active site
Descriptor: Beta-lactamase OXA-58
Authors:Pratap, S, Gill, P.K, Golemi-Kotra, D, Kumar, P.
Deposit date:2015-04-11
Release date:2016-04-13
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Crystal structure of OXA-58 with disordered active site
To Be Published
4ZPE
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BU of 4zpe by Molmil
BACE1 in complex with 4-(cyclohexylamino)-1-(3-fluorophenyl)-8-(3-isopropoxybenzyl)-1,3,8-triazaspiro[4.5]dec-3-en-2-one
Descriptor: 4-(cyclohexylamino)-1-(3-fluorophenyl)-8-[3-(propan-2-yloxy)benzyl]-1,3,8-triazaspiro[4.5]dec-3-en-2-one, Beta-secretase 1
Authors:Orth, P.
Deposit date:2015-05-07
Release date:2015-08-05
Last modified:2015-10-28
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Methyl-substitution of an iminohydantoin spiropiperidine beta-secretase (BACE-1) inhibitor has a profound effect on its potency.
Bioorg.Med.Chem.Lett., 25, 2015
4ZL8
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BU of 4zl8 by Molmil
Crystal structure of Pseudomonas aeruginosa DsbA E82I: Crystal II
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, Thiol:disulfide interchange protein DsbA
Authors:McMahoh, R.M, Martin, J.L.
Deposit date:2015-05-01
Release date:2015-12-09
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.395 Å)
Cite:Sent packing: protein engineering generates a new crystal form of Pseudomonas aeruginosa DsbA1 with increased catalytic surface accessibility.
Acta Crystallogr. D Biol. Crystallogr., 71, 2015
4ZO1
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BU of 4zo1 by Molmil
Crystal Structure of the T3-bound TR-beta Ligand-binding Domain in complex with RXR-alpha
Descriptor: 3,5,3'TRIIODOTHYRONINE, Nuclear receptor coactivator 2, Retinoic acid receptor RXR-alpha, ...
Authors:Bruning, J.B, Kojetin, D.J, Matta-Camacho, E, Hughes, T.S, Srinivasan, S, Nwachukwu, J.C, Cavett, V, Nowak, J, Chalmers, M.J, Marciano, D.P, Kamenecka, T.M, Rance, M, Shulman, A.I, Mangelsdorf, D.J, Griffin, P.R, Nettles, K.W.
Deposit date:2015-05-05
Release date:2015-09-02
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.221 Å)
Cite:Structural mechanism for signal transduction in RXR nuclear receptor heterodimers.
Nat Commun, 6, 2015
4ZPF
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BU of 4zpf by Molmil
BACE1 in complex with 8-(3-((1-aminopropan-2-yl)oxy)benzyl)-4-(cyclohexylamino)-1-(3-fluorophenyl)-1,3,8-triazaspiro[4.5]dec-3-en-2-one
Descriptor: 8-(3-{[(2S)-1-aminopropan-2-yl]oxy}benzyl)-4-(cyclohexylamino)-1-(3-fluorophenyl)-1,3,8-triazaspiro[4.5]dec-3-en-2-one, Beta-secretase 1
Authors:Orth, P.
Deposit date:2015-05-07
Release date:2015-08-05
Last modified:2015-10-28
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Methyl-substitution of an iminohydantoin spiropiperidine beta-secretase (BACE-1) inhibitor has a profound effect on its potency.
Bioorg.Med.Chem.Lett., 25, 2015
3TD4
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BU of 3td4 by Molmil
Crystal structure of OmpA-like domain from Acinetobacter baumannii in complex with diaminopimelate
Descriptor: 2,6-DIAMINOPIMELIC ACID, Outer membrane protein omp38
Authors:Park, J.S, Lee, W.C, Song, J.H, Kim, H.Y.
Deposit date:2011-08-10
Release date:2011-10-26
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Mechanism of anchoring of OmpA protein to the cell wall peptidoglycan of the gram-negative bacterial outer membrane
Faseb J., 26, 2012

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數據於2024-07-17公開中

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