4KQQ
CRYSTAL STRUCTURE OF PENICILLIN-BINDING PROTEIN 3 FROM PSEUDOMONAS AERUGINOSA IN COMPLEX WITH (5S)-Penicilloic Acid
Summary for 4KQQ
Entry DOI | 10.2210/pdb4kqq/pdb |
Related | 4KQO 4KQR |
Descriptor | Penicillin-binding protein 3, (2S,4S)-2-[(R)-carboxy{[(2R)-2-{[(4-ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino}-2-phenylacetyl]amino}methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, CHLORIDE ION, ... (6 entities in total) |
Functional Keywords | penicillin-binding proteins, piperacillin, (5s)-penicilloic acid, cell wall biosynthesis, transpeptidase, out periplasmic membrane, biosynthetic protein, biosynthetic protein-antibiotic complex, biosynthetic protein/antibiotic |
Biological source | Pseudomonas aeruginosa |
Total number of polymer chains | 2 |
Total formula weight | 124012.23 |
Authors | Nettleship, J.E.,Stuart, D.I.,Owens, R.J.,Ren, J. (deposition date: 2013-05-15, release date: 2013-11-06, Last modification date: 2023-09-20) |
Primary citation | van Berkel, S.S.,Nettleship, J.E.,Leung, I.K.,Brem, J.,Choi, H.,Stuart, D.I.,Claridge, T.D.,McDonough, M.A.,Owens, R.J.,Ren, J.,Schofield, C.J. Binding of (5S)-Penicilloic Acid to Penicillin Binding Protein 3. Acs Chem.Biol., 8:2112-2116, 2013 Cited by PubMed: 23899657DOI: 10.1021/cb400200h PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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