4YXR

CRYSTAL STRUCTURE OF PKA IN COMPLEX WITH inhibitor.

Summary for 4YXR

Entry DOI	10.2210/pdb4yxr/pdb
Descriptor	cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha, 3-methyl-2H-indazole, ... (4 entities in total)
Functional Keywords	complex (phosphotransferase-inhibitor) complex, transferase
Biological source	Bos taurus (Bovine) More
Cellular location	Cytoplasm : P00517
Total number of polymer chains	2
Total formula weight	43065.98
Authors	Schiffer, A.,Wendt, K.U. (deposition date: 2015-03-23, release date: 2015-05-27, Last modification date: 2015-06-03)
Primary citation	Pilger, J.,Mazur, A.,Monecke, P.,Schreuder, H.,Elshorst, B.,Bartoschek, S.,Langer, T.,Schiffer, A.,Krimm, I.,Wegstroth, M.,Lee, D.,Hessler, G.,Wendt, K.U.,Becker, S.,Griesinger, C. A combination of spin diffusion methods for the determination of protein-ligand complex structural ensembles. Angew.Chem.Int.Ed.Engl., 54:6511-6515, 2015 Cited by PubMed: 25877959 DOI: 10.1002/anie.201500671 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation