4YXR
CRYSTAL STRUCTURE OF PKA IN COMPLEX WITH inhibitor.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | cAMP-dependent protein kinase catalytic subunit alpha | polymer | 350 | 40707.4 | 1 | UniProt (P00517) Pfam (PF00069) | Bos taurus (Bovine) | PKA C-alpha |
| 2 | B (I) | cAMP-dependent protein kinase inhibitor alpha | polymer | 20 | 2226.4 | 1 | UniProt (Q3SX13) | Bos taurus (Bovine) | PKI-alpha |
| 3 | C (A) | 3-methyl-2H-indazole | non-polymer | 132.2 | 1 | Chemie (0RW) | |||
| 4 | D, E (A, I) | water | water | 18.0 | 317 | Chemie (HOH) |
Sequence modifications
A: 1 - 350 (UniProt: P00517)
| PDB | External Database | Details |
|---|---|---|
| Asp 286 | Asn 287 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 42933.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 132.2 | |
| All* | Total formula weight | 43066.0 |
