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6Q0L
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Inferred intermediate I-7 (I-7-1) of the human antibody lineage 652 in complex with influenza hemagglutinin head domain of A/Beijing/262/95(H1N1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab heavy chain, Fab lambda chain, ...
Authors:McCarthy, K.R, Harrison, S.C.
Deposit date:2019-08-01
Release date:2019-12-18
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Affinity maturation in a human humoral response to influenza hemagglutinin.
Proc.Natl.Acad.Sci.USA, 2019
6Q0I
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BU of 6q0i by Molmil
Inferred intermediate I-7 (I-7-6) of the human antibody lineage 652 in complex with influenza hemagglutinin head domain of A/Beijing/262/95(H1N1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab heavy chain, Fab lambda chain, ...
Authors:McCarthy, K.R, Harrison, S.C.
Deposit date:2019-08-01
Release date:2019-12-18
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.702 Å)
Cite:Affinity maturation in a human humoral response to influenza hemagglutinin.
Proc.Natl.Acad.Sci.USA, 2019
6Q1K
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Inferred intermediate I-7 of the human antibody lineage 652
Descriptor: Fab heavy chain, Fab lambda light chain, GLYCEROL
Authors:McCarthy, K.R, Harrison, S.C.
Deposit date:2019-08-05
Release date:2019-12-18
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Affinity maturation in a human humoral response to influenza hemagglutinin.
Proc.Natl.Acad.Sci.USA, 2019
6O5R
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BU of 6o5r by Molmil
Room temperature structure of binary complex of native hAChE with oxime reactivator RS-170B
Descriptor: 4-carbamoyl-1-(3-{2-[(E)-(hydroxyimino)methyl]-1H-imidazol-1-yl}propyl)pyridin-1-ium, Acetylcholinesterase, CHLORIDE ION
Authors:Gerlits, O, Kovalevsky, A, Radic, Z.
Deposit date:2019-03-04
Release date:2019-05-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Productive reorientation of a bound oxime reactivator revealed in room temperature X-ray structures of native and VX-inhibited human acetylcholinesterase.
J.Biol.Chem., 294, 2019
6Q0E
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Inferred precursor (UCA) of the human antibody lineage 652 in complex with influenza hemagglutinin head domain of A/Beijing/262/95(H1N1)
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Fab heavy chain, Fab lambda light chain, ...
Authors:McCarthy, K.R, Harrison, S.C.
Deposit date:2019-08-01
Release date:2019-12-18
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Affinity maturation in a human humoral response to influenza hemagglutinin.
Proc.Natl.Acad.Sci.USA, 2019
6Q0O
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human antibody H2227 lineage 652 in complex with influenza hemagglutinin head domain of A/Solomon Islands/3/2006(H1N1)
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ...
Authors:McCarthy, K.R, Harrison, S.C.
Deposit date:2019-08-02
Release date:2019-12-18
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3 Å)
Cite:Affinity maturation in a human humoral response to influenza hemagglutinin.
Proc.Natl.Acad.Sci.USA, 2019
6QJP
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BU of 6qjp by Molmil
Cryo-EM structure of heparin-induced 2N4R tau jagged filaments
Descriptor: Microtubule-associated protein tau
Authors:Zhang, W, Falcon, B, Murzin, A.G, Fan, J, Crowther, R.A, Goedert, M, Scheres, S.H.W.
Deposit date:2019-01-24
Release date:2019-02-20
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Heparin-induced tau filaments are polymorphic and differ from those in Alzheimer's and Pick's diseases.
Elife, 8, 2019
6QJH
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Cryo-EM structure of heparin-induced 2N4R tau snake filaments
Descriptor: Microtubule-associated protein tau
Authors:Zhang, W, Falcon, B, Murzin, A.G, Fan, J, Crowther, R.A, Goedert, M, Scheres, S.H.W.
Deposit date:2019-01-24
Release date:2019-02-20
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Heparin-induced tau filaments are polymorphic and differ from those in Alzheimer's and Pick's diseases.
Elife, 8, 2019
6QJM
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Cryo-EM structure of heparin-induced 2N4R tau twister filaments
Descriptor: Microtubule-associated protein tau
Authors:Zhang, W, Falcon, B, Murzin, A.G, Fan, J, Crowther, R.A, Goedert, M, Scheres, S.H.W.
Deposit date:2019-01-24
Release date:2019-02-27
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Heparin-induced tau filaments are polymorphic and differ from those in Alzheimer's and Pick's diseases.
Elife, 8, 2019
6QJQ
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BU of 6qjq by Molmil
Cryo-EM structure of heparin-induced 2N3R tau filaments
Descriptor: Microtubule-associated protein tau
Authors:Zhang, W, Falcon, B, Murzin, A.G, Fan, J, Crowther, R.A, Goedert, M, Scheres, S.H.W.
Deposit date:2019-01-24
Release date:2019-02-20
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Heparin-induced tau filaments are polymorphic and differ from those in Alzheimer's and Pick's diseases.
Elife, 8, 2019
8BM7
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Hairpin adopted by oligonucleotide A38 found in the promoter of AUTS2 gene.
Descriptor: A38
Authors:Novotny, A.
Deposit date:2022-11-10
Release date:2023-02-22
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Structural polymorphism driven by a register shift in a CGAG-rich region found in the promoter of the neurodevelopmental regulator AUTS2 gene.
Nucleic Acids Res., 51, 2023
8BM6
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BU of 8bm6 by Molmil
Hairpin adopted by oligonucleotide A36 found in the promoter of AUTS2 gene
Descriptor: A36
Authors:Novotny, A.
Deposit date:2022-11-10
Release date:2023-02-22
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Structural polymorphism driven by a register shift in a CGAG-rich region found in the promoter of the neurodevelopmental regulator AUTS2 gene.
Nucleic Acids Res., 51, 2023
8BM4
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BU of 8bm4 by Molmil
Hairpin adopted by modified oligonucleotide A32_mod found in the promoter of AUTS2 gene.
Descriptor: A32_mod
Authors:Novotny, A.
Deposit date:2022-11-10
Release date:2023-02-22
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Structural polymorphism driven by a register shift in a CGAG-rich region found in the promoter of the neurodevelopmental regulator AUTS2 gene.
Nucleic Acids Res., 51, 2023
8OWD
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BU of 8owd by Molmil
Lipidic amyloid-beta(1-40) fibril - polymorph L3
Descriptor: Amyloid-beta A4 protein
Authors:Frieg, B, Han, M, Giller, K, Dienemann, C, Riedel, D, Becker, S, Andreas, L.B, Griesinger, C, Schroeder, G.F.
Deposit date:2023-04-27
Release date:2024-03-06
Method:ELECTRON MICROSCOPY (3.28 Å)
Cite:Cryo-EM structures of lipidic fibrils of amyloid-beta (1-40).
Nat Commun, 15, 2024
8OVK
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BU of 8ovk by Molmil
Lipidic amyloid-beta(1-40) fibril - polymorph L1
Descriptor: Amyloid-beta A4 protein
Authors:Frieg, B, Han, M, Giller, K, Dienemann, C, Riedel, D, Becker, S, Andreas, L.B, Griesinger, C, Schroeder, G.F.
Deposit date:2023-04-26
Release date:2024-03-06
Method:ELECTRON MICROSCOPY (2.88 Å)
Cite:Cryo-EM structures of lipidic fibrils of amyloid-beta (1-40).
Nat Commun, 15, 2024
8OWJ
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BU of 8owj by Molmil
Lipidic amyloid-beta(1-40) fibril - polymorph L2-L2
Descriptor: Amyloid-beta A4 protein
Authors:Frieg, B, Han, M, Giller, K, Dienemann, C, Riedel, D, Becker, S, Andreas, L.B, Griesinger, C, Schroeder, G.F.
Deposit date:2023-04-28
Release date:2024-03-06
Method:ELECTRON MICROSCOPY (3.75 Å)
Cite:Cryo-EM structures of lipidic fibrils of amyloid-beta (1-40).
Nat Commun, 15, 2024
8OWE
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BU of 8owe by Molmil
Lipidic amyloid-beta(1-40) fibril - polymorph L2-L3
Descriptor: Amyloid-beta A4 protein
Authors:Frieg, B, Han, M, Giller, K, Dienemann, C, Riedel, D, Becker, S, Andreas, L.B, Griesinger, C, Schroeder, G.F.
Deposit date:2023-04-27
Release date:2024-03-06
Method:ELECTRON MICROSCOPY (3.75 Å)
Cite:Cryo-EM structures of lipidic fibrils of amyloid-beta (1-40).
Nat Commun, 15, 2024
8OXE
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BU of 8oxe by Molmil
Inositol 1,3,4-trisphosphate 5/6-kinase 1 from Solanum tuberosum (StITPK1) in complex with ADP/Mg2+
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Inositol-tetrakisphosphate 1-kinase, MAGNESIUM ION
Authors:Faba-Rodriguez, R, Li, A.W.H, Brearley, C.A, Hemmings, A.M.
Deposit date:2023-05-02
Release date:2024-03-27
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Crystal Structure and Enzymology of Solanum tuberosum Inositol Tris/Tetrakisphosphate Kinase 1 ( St ITPK1).
Biochemistry, 63, 2024
8OWK
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BU of 8owk by Molmil
Lipidic amyloid-beta(1-40) fibril - polymorph L3-L3
Descriptor: Amyloid-beta A4 protein
Authors:Frieg, B, Han, M, Giller, K, Dienemann, C, Riedel, D, Becker, S, Andreas, L.B, Griesinger, C, Schroeder, G.F.
Deposit date:2023-04-28
Release date:2024-03-06
Method:ELECTRON MICROSCOPY (3.86 Å)
Cite:Cryo-EM structures of lipidic fibrils of amyloid-beta (1-40).
Nat Commun, 15, 2024
8PPO
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BU of 8ppo by Molmil
First Intermediate Amyloid (FIA) - Tau
Descriptor: Microtubule-associated protein tau
Authors:Lovestam, S, Scheres, S.H.W, Goedert, M, Li, D.
Deposit date:2023-07-07
Release date:2023-08-02
Last modified:2024-01-24
Method:ELECTRON MICROSCOPY (2 Å)
Cite:Disease-specific tau filaments assemble via polymorphic intermediates.
Nature, 625, 2024
8Q7M
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BU of 8q7m by Molmil
Tau - AD-MIA7 (tau intermediate amyloid)
Descriptor: Isoform Tau-D of Microtubule-associated protein tau
Authors:Lovestam, S, Li, D, Scheres, S.H.W, Goedert, M.
Deposit date:2023-08-16
Release date:2023-08-30
Last modified:2024-01-24
Method:ELECTRON MICROSCOPY (3.26 Å)
Cite:Disease-specific tau filaments assemble via polymorphic intermediates.
Nature, 625, 2024
8Q8D
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BU of 8q8d by Molmil
Tau - AD-LIA6 (tau intermediate amyloid)
Descriptor: Isoform Tau-D of Microtubule-associated protein tau
Authors:Lovestam, S, Li, D, Scheres, S.H.W, Goedert, M.
Deposit date:2023-08-18
Release date:2023-08-30
Last modified:2024-01-24
Method:ELECTRON MICROSCOPY (3.04 Å)
Cite:Disease-specific tau filaments assemble via polymorphic intermediates.
Nature, 625, 2024
8Q2J
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BU of 8q2j by Molmil
Tau - AD-MIA2
Descriptor: Isoform Tau-D of Microtubule-associated protein tau
Authors:Lovestam, S, Li, D, Scheres, S.H.W, Goedert, M.
Deposit date:2023-08-02
Release date:2023-08-30
Last modified:2024-01-24
Method:ELECTRON MICROSCOPY (2.23 Å)
Cite:Disease-specific tau filaments assemble via polymorphic intermediates.
Nature, 625, 2024
8Q7F
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BU of 8q7f by Molmil
Tau - AD-MIA5
Descriptor: Isoform Tau-D of Microtubule-associated protein tau
Authors:Lovestam, S, Li, D, Scheres, S.H.W, Goedert, M.
Deposit date:2023-08-16
Release date:2023-08-30
Last modified:2024-01-24
Method:ELECTRON MICROSCOPY (3.72 Å)
Cite:Disease-specific tau filaments assemble via polymorphic intermediates.
Nature, 625, 2024
8Q8C
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BU of 8q8c by Molmil
Tau - AD-MIA10 (intermediate amyloid)
Descriptor: Isoform Tau-D of Microtubule-associated protein tau
Authors:Lovestam, S, Li, D, Scheres, S.H.W, Goedert, M.
Deposit date:2023-08-18
Release date:2023-09-06
Last modified:2024-01-24
Method:ELECTRON MICROSCOPY (1.92 Å)
Cite:Disease-specific tau filaments assemble via polymorphic intermediates.
Nature, 625, 2024

223790

數據於2024-08-14公開中

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