5IFZ
 
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4KSP
 | | Crystal Structure of Human B-raf bound to a DFG-out Inhibitor TAK-632 | | Descriptor: | N-{7-cyano-6-[4-fluoro-3-({[3-(trifluoromethyl)phenyl]acetyl}amino)phenoxy]-1,3-benzothiazol-2-yl}cyclopropanecarboxamide, Serine/threonine-protein kinase B-raf | | Authors: | Yano, J.K, Masanori, O. | | Deposit date: | 2013-05-17 | | Release date: | 2013-07-24 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.93 Å) | | Cite: | Discovery of a Selective Kinase Inhibitor (TAK-632) Targeting Pan-RAF Inhibition: Design, Synthesis, and Biological Evaluation of C-7-Substituted 1,3-Benzothiazole Derivatives.
J.Med.Chem., 56, 2013
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5IIT
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4KOD
 | | Structure of p97 N-D1 R155H mutant in complex with ADP | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase | | Authors: | Xia, D, Tang, W.K. | | Deposit date: | 2013-05-11 | | Release date: | 2013-11-13 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.96 Å) | | Cite: | Altered Intersubunit Communication Is the Molecular Basis for Functional Defects of Pathogenic p97 Mutants.
J.Biol.Chem., 288, 2013
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4K22
 | | Structure of the C-terminal truncated form of E.Coli C5-hydroxylase UBII involved in ubiquinone (Q8) biosynthesis | | Descriptor: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | | Authors: | Pecqueur, L, Lombard, M, Golinelli-pimpaneau, B, Fontecave, M. | | Deposit date: | 2013-04-07 | | Release date: | 2013-05-29 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | ubiI, a New Gene in Escherichia coli Coenzyme Q Biosynthesis, Is Involved in Aerobic C5-hydroxylation.
J.Biol.Chem., 288, 2013
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4K2H
 | | Crystal structure of C103A mutant of DJ-1 superfamily protein STM1931 from Salmonella typhimurium | | Descriptor: | Intracellular protease/amidase, ZINC ION | | Authors: | Shumilin, I.A, Niedzialkowska, E, Domagalski, M.J, Stam, J, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2013-04-09 | | Release date: | 2013-04-24 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal structure of C103A mutant of DJ-1 superfamily protein STM1931 from Salmonella typhimurium
TO BE PUBLISHED
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1T1A
 | | Late intermediate IL1 from time-resolved crystallography of the E46Q mutant of PYP | | Descriptor: | 4'-HYDROXYCINNAMIC ACID, Photoactive yellow protein | | Authors: | Rajagopal, S, Anderson, S, Srajer, V, Schmidt, M, Pahl, R, Moffat, K. | | Deposit date: | 2004-04-15 | | Release date: | 2005-01-18 | | Last modified: | 2021-10-27 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | A Structural Pathway for Signaling in the E46Q Mutant of Photoactive Yellow Protein
Structure, 13, 2005
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1SXW
 | | 1.05 A Crystal Structure of D30A Mutant of Nitrophorin 4 from Rhodnius Prolixus Complexed with Nitric Oxide | | Descriptor: | NITRIC OXIDE, Nitrophorin 4, PHOSPHATE ION, ... | | Authors: | Maes, E.M, Weichsel, A, Andersen, J.F, Shepley, D, Montfort, W.R. | | Deposit date: | 2004-03-31 | | Release date: | 2004-06-08 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.05 Å) | | Cite: | Role of binding site loops in controlling nitric oxide release: structure and kinetics of mutant forms of nitrophorin 4
Biochemistry, 43, 2004
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1T19
 | | Early intermediate IE2 from time-resolved crystallography of the E46Q mutant of PYP | | Descriptor: | 4'-HYDROXYCINNAMIC ACID, Photoactive yellow protein | | Authors: | Rajagopal, S, Anderson, S, Srajer, V, Schmidt, M, Pahl, R, Moffat, K. | | Deposit date: | 2004-04-15 | | Release date: | 2005-01-18 | | Last modified: | 2021-10-27 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | A Structural Pathway for Signaling in the E46Q Mutant of Photoactive Yellow Protein
Structure, 13, 2005
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1T9C
 | | Crystal Structure Of Yeast Acetohydroxyacid Synthase In Complex With A Sulfonylurea Herbicide, Sulfometuron methyl | | Descriptor: | Acetolactate synthase, mitochondrial, ETHYL DIHYDROGEN DIPHOSPHATE, ... | | Authors: | McCourt, J.A, Pang, S.S, Guddat, L.W, Duggleby, R.G. | | Deposit date: | 2004-05-16 | | Release date: | 2004-12-21 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.34 Å) | | Cite: | Elucidating the specificity of binding of sulfonylurea herbicides to acetohydroxyacid synthase.
Biochemistry, 44, 2005
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5IPM
 | | SigmaS-transcription initiation complex with 4-nt nascent RNA | | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | Authors: | Liu, B, Zuo, Y, Steitz, T.A. | | Deposit date: | 2016-03-09 | | Release date: | 2016-03-30 | | Last modified: | 2016-06-22 | | Method: | X-RAY DIFFRACTION (4.2 Å) | | Cite: | Structures of E. coli sigma S-transcription initiation complexes provide new insights into polymerase mechanism.
Proc.Natl.Acad.Sci.USA, 113, 2016
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1T68
 | | Crystal structure of nitrophorin 2 complex with NO | | Descriptor: | NITRIC OXIDE, Nitrophorin 2, PROTOPORPHYRIN IX CONTAINING FE | | Authors: | Weichsel, A, Montfort, W.R. | | Deposit date: | 2004-05-05 | | Release date: | 2005-05-17 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | Conformational change and heme ruffling in nitrophorin 2, a nitric oxide carrier from kissing bug
To be Published
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5I7C
 | | Centrosomin-motif 2 (CM2) domain of Drosophila melanogaster Centrosomin (Cnn) | | Descriptor: | Centrosomin, ZINC ION | | Authors: | Feng, Z, Cottee, M.A, Johnson, S, Lea, S.M. | | Deposit date: | 2016-02-17 | | Release date: | 2017-03-08 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.804 Å) | | Cite: | Structural Basis for Mitotic Centrosome Assembly in Flies.
Cell, 169, 2017
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1TJM
 | | Crystallographic Identification of Sr2+ Coordination Site in Synaptotagmin I C2B Domain | | Descriptor: | GLYCEROL, STRONTIUM ION, Synaptotagmin I | | Authors: | Cheng, Y, Sequeira, S.M, Malinina, L, Tereshko, V, Sollner, T.H, Patel, D.J. | | Deposit date: | 2004-06-06 | | Release date: | 2004-09-28 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.18 Å) | | Cite: | Crystallographic identification of Ca2+ and Sr2+ coordination sites in synaptotagmin I C2B domain
Protein Sci., 13, 2004
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1IO7
 | | THERMOPHILIC CYTOCHROME P450 (CYP119) FROM SULFOLOBUS SOLFATARICUS: HIGH RESOLUTION STRUCTURAL ORIGIN OF ITS THERMOSTABILITY AND FUNCTIONAL PROPERTIES | | Descriptor: | CYTOCHROME P450 CYP119, PROTOPORPHYRIN IX CONTAINING FE | | Authors: | Park, S.-Y, Yamane, K, Adachi, S, Shiro, Y, Sligar, S.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2001-02-08 | | Release date: | 2001-02-28 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Thermophilic cytochrome P450 (CYP119) from Sulfolobus solfataricus: high resolution structure and functional properties.
J.Inorg.Biochem., 91, 2002
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5IMS
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1J6Z
 | | UNCOMPLEXED ACTIN | | Descriptor: | ACTIN ALPHA 1, ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, ... | | Authors: | Otterbein, L.R, Graceffa, P, Dominguez, R. | | Deposit date: | 2001-05-15 | | Release date: | 2001-08-15 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.54 Å) | | Cite: | The crystal structure of uncomplexed actin in the ADP state.
Science, 293, 2001
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5I8N
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5IUZ
 | | STRUCTURE OF P450 2B4 F202W MUTANT (CYMAL-5) | | Descriptor: | 5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE, Cytochrome P450 2B4, PROTOPORPHYRIN IX CONTAINING FE | | Authors: | Jang, H.-H, Halpert, J.R, Shah, M.B. | | Deposit date: | 2016-03-18 | | Release date: | 2016-06-08 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.73 Å) | | Cite: | Effect of detergent binding on cytochrome P450 2B4 structure as analyzed by X-ray crystallography and deuterium-exchange mass spectrometry.
Biophys.Chem., 216, 2016
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5IVB
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1J5U
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1TS8
 | | Structure of the pR cis planar intermediate from time-resolved Laue crystallography | | Descriptor: | 4'-HYDROXYCINNAMIC ACID, Photoactive yellow protein | | Authors: | Ihee, H, Rajagopal, S, Srajer, V, Pahl, R, Anderson, S, Schmidt, M, Schotte, F, Anfinrud, P.A, Wulff, M, Moffat, K. | | Deposit date: | 2004-06-21 | | Release date: | 2005-07-05 | | Last modified: | 2017-10-11 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Visualizing reaction pathways in photoactive yellow protein from nanoseconds to seconds.
Proc.Natl.Acad.Sci.Usa, 102, 2005
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1TV3
 | | Crystal structure of the N-methyl-hydroxylamine MtmB complex | | Descriptor: | 5-(HYDROXY-METHYL-AMINO)-3-METHYL-PYRROLIDINE-2-CARBOXYLIC ACID, Monomethylamine methyltransferase mtmB1 | | Authors: | Hao, B, Zhao, G, Kang, P.T, Soares, J.A, Ferguson, T.K, Gallucci, J, Krzycki, J.A, Chan, M.K. | | Deposit date: | 2004-06-26 | | Release date: | 2004-10-19 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Reactivity and chemical synthesis of L-pyrrolysine- the 22(nd) genetically encoded amino acid
Chem.Biol., 11, 2004
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5J7C
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1JA0
 | | CYPOR-W677X | | Descriptor: | FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | Authors: | Hubbard, P.A, Shen, A.L, Paschke, R, Kasper, C.B, Kim, J.J. | | Deposit date: | 2001-05-29 | | Release date: | 2001-08-22 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | NADPH-cytochrome P450 oxidoreductase. Structural basis for hydride and electron transfer.
J.Biol.Chem., 276, 2001
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