Crystal Structure Of Yeast Acetohydroxyacid Synthase In Complex With A Sulfonylurea Herbicide, Sulfometuron methyl

Summary for 1T9C

Related1N0H 1T9B 1T9A 1T9D
DescriptorAcetolactate synthase, mitochondrial, POTASSIUM ION, MAGNESIUM ION, ... (8 entities in total)
Functional Keywordsacetohydroxyacid synthase, acetolactate synthase, herbicide, sulfonylurea, thiamin diphosphate, fad, inhibitor, sulfometuron methyl, transferase
Biological sourceSaccharomyces cerevisiae (baker's yeast)
Cellular locationMitochondrion P07342
Total number of polymer chains2
Total molecular weight150048.05
McCourt, J.A.,Pang, S.S.,Guddat, L.W.,Duggleby, R.G. (deposition date: 2004-05-16, release date: 2004-12-21, Last modification date: 2017-10-11)
Primary citation
McCourt, J.A.,Pang, S.S.,Guddat, L.W.,Duggleby, R.G.
Elucidating the specificity of binding of sulfonylurea herbicides to acetohydroxyacid synthase.
Biochemistry, 44:2330-2338, 2005
PubMed: 15709745 (PDB entries with the same primary citation)
DOI: 10.1021/bi047980a
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.19270.1%1.6%1.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-07-29