1T9B

Crystal structure of yeast acetohydroxyacid synthase in complex with a sulfonylurea herbicide, chlorsulfuron

Summary for 1T9B

Related1N0H 1T9C 1T9D 1T9A
DescriptorAcetolactate synthase, mitochondrial, POTASSIUM ION, MAGNESIUM ION, ... (10 entities in total)
Functional Keywordsacetohydroxyacid synthase, acetolactate synthase, herbicide, sulfonylurea, thiamin diphosphate, fad, inhibitor, chlorsulfuron, transferase
Biological sourceSaccharomyces cerevisiae (baker's yeast)
Cellular locationMitochondrion P07342
Total number of polymer chains2
Total molecular weight150413.39
Authors
McCourt, J.A.,Pang, S.S.,Guddat, L.W.,Duggleby, R.G. (deposition date: 2004-05-16, release date: 2004-12-21, Last modification date: 2017-10-11)
Primary citation
McCourt, J.A.,Pang, S.S.,Guddat, L.W.,Duggleby, R.G.
Elucidating the specificity of binding of sulfonylurea herbicides to acetohydroxyacid synthase.
Biochemistry, 44:2330-2338, 2005
PubMed: 15709745 (PDB entries with the same primary citation)
DOI: 10.1021/bi047980a
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.2 Å)
?

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.19680.1%1.5%1.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
167518
PDB entries from 2020-08-12