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4LJZ
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BU of 4ljz by Molmil
Crystal Structure Analysis of the E.coli holoenzyme
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Bae, B, Darst, S.A.
Deposit date:2013-07-05
Release date:2013-11-13
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.5871 Å)
Cite:Phage T7 Gp2 inhibition of Escherichia coli RNA polymerase involves misappropriation of sigma 70 domain 1.1.
Proc.Natl.Acad.Sci.USA, 110, 2013
1HZ2
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BU of 1hz2 by Molmil
SOLUTION NMR STRUCTURE OF SELF-COMPLEMENTARY DUPLEX 5'-D(AGGCG*CCT)2 CONTAINING A TRIMETHYLENE CROSSLINK AT THE N2 POSITION OF G*. MODEL OF A MALONDIALDEHYDE CROSSLINK
Descriptor: DNA (5'-D(*AP*GP*GP*CP*GP*CP*CP*T)-3'), PROPANE
Authors:Dooley, P.A, Tsarouhtsis, D, Korbel, G.A, Nechev, L.V, Shearer, J, Zegar, I.S, Harris, C.M, Stone, M.P, Harris, T.M.
Deposit date:2001-01-23
Release date:2001-02-07
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structural studies of an oligodeoxynucleotide containing a trimethylene interstrand cross-link in a 5'-(CpG) motif: model of a malondialdehyde cross-link.
J.Am.Chem.Soc., 123, 2001
6R1T
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BU of 6r1t by Molmil
Structure of LSD2/NPAC-linker/nucleosome core particle complex: Class 1, free nuclesome
Descriptor: DNA (147-MER), HISTONE H2A, Histone H2A, ...
Authors:Marabelli, C, Pilotto, S, Chittori, S, Subramaniam, S, Mattevi, A.
Deposit date:2019-03-15
Release date:2019-04-24
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (4.02 Å)
Cite:A Tail-Based Mechanism Drives Nucleosome Demethylation by the LSD2/NPAC Multimeric Complex.
Cell Rep, 27, 2019
6R1U
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BU of 6r1u by Molmil
Structure of LSD2/NPAC-linker/nucleosome core particle complex: Class 2
Descriptor: DNA (147-MER), FLAVIN-ADENINE DINUCLEOTIDE, Histone H2A, ...
Authors:Marabelli, C, Pilotto, S, Chittori, S, Subramaniam, S, Mattevi, A.
Deposit date:2019-03-15
Release date:2019-04-24
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (4.36 Å)
Cite:A Tail-Based Mechanism Drives Nucleosome Demethylation by the LSD2/NPAC Multimeric Complex.
Cell Rep, 27, 2019
6NSM
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BU of 6nsm by Molmil
TetR family transcriptional regulator CifR C99T-C107S-C181R Cysteines mutant complexed with 26bp double-strand operator DNA
Descriptor: DNA (26-MER), TetR family transcriptional regulator CifR
Authors:He, S, Simard, A.R, Madden, D.R.
Deposit date:2019-01-25
Release date:2020-01-29
Last modified:2024-07-17
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Molecular basis for the transcriptional regulation of an epoxide-based virulence circuit in Pseudomonas aeruginosa
Biorxiv, 2024
7YP9
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BU of 7yp9 by Molmil
Cryo-EM structure of Escherichia coli paused complex of transcription termination (TTC-pause)
Descriptor: DNA (31-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:You, L.L, Zhang, Y.
Deposit date:2022-08-03
Release date:2022-11-16
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.58 Å)
Cite:Structural basis for intrinsic transcription termination.
Nature, 613, 2023
7YPA
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BU of 7ypa by Molmil
Cryo-EM structure of Escherichia coli hairpin-nucleation complex of transcription termination (TTC-hairpin)
Descriptor: DNA (31-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:You, L.L, Zhang, Y.
Deposit date:2022-08-03
Release date:2022-11-16
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.05 Å)
Cite:Structural basis for intrinsic transcription termination.
Nature, 613, 2023
8Q3B
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BU of 8q3b by Molmil
The closed state of the ASFV apo-RNA polymerase
Descriptor: DNA-directed RNA polymerase RPB1 homolog, DNA-directed RNA polymerase RPB10 homolog, DNA-directed RNA polymerase RPB2 homolog, ...
Authors:Pilotto, S, Sykora, M, Cackett, G, Werner, F.
Deposit date:2023-08-03
Release date:2024-02-14
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (2.69 Å)
Cite:Structure of the recombinant RNA polymerase from African Swine Fever Virus.
Nat Commun, 15, 2024
8Q3K
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BU of 8q3k by Molmil
The open state of the ASFV apo-RNA polymerase
Descriptor: DNA-directed RNA polymerase RPB1 homolog, DNA-directed RNA polymerase RPB10 homolog, DNA-directed RNA polymerase RPB2 homolog, ...
Authors:Pilotto, S, Sykora, M, Cackett, G, Werner, F.
Deposit date:2023-08-04
Release date:2024-02-14
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (2.92 Å)
Cite:Structure of the recombinant RNA polymerase from African Swine Fever Virus.
Nat Commun, 15, 2024
6DZT
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BU of 6dzt by Molmil
Cryo-EM structure of nucleosome in complex with a single chain antibody fragment
Descriptor: DNA (147-MER), Histone H2A, Histone H2B, ...
Authors:Yadav, K.N.S, Zhou, B.-R.
Deposit date:2018-07-05
Release date:2019-05-22
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (2.99 Å)
Cite:Atomic resolution cryo-EM structure of a native-like CENP-A nucleosome aided by an antibody fragment.
Nat Commun, 10, 2019
6MGM
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BU of 6mgm by Molmil
Helix-Loop-helix motif of mouse DNA-binding protein inhibitor ID-1
Descriptor: DNA-binding protein inhibitor ID-1
Authors:Benezra, R, Pavletich, N.P, Goldgur, Y, Gall, A.-L.
Deposit date:2018-09-14
Release date:2019-09-18
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.791 Å)
Cite:A Small-Molecule Pan-Id Antagonist Inhibits Pathologic Ocular Neovascularization.
Cell Rep, 29, 2019
8TXO
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BU of 8txo by Molmil
E. coli DNA-directed RNA polymerase transcription elongation complex bound to the unnatural dZ-PTP base pair in the active site
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Aiyer, S, Shan, Z, Oh, J, Wang, D, Tan, Y.Z, Lyumkis, D.
Deposit date:2023-08-23
Release date:2024-01-24
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Overcoming resolution attenuation during tilted cryo-EM data collection.
Nat Commun, 15, 2024
5OLA
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BU of 5ola by Molmil
Structure of mitochondrial transcription elongation complex in complex with elongation factor TEFM
Descriptor: DNA (30-MER), DNA (5'-D(P*AP*TP*GP*GP*TP*GP*TP*AP*AP*CP*GP*CP*CP*AP*GP*AP*CP*GP*AP*AP*C)-3'), DNA-directed RNA polymerase, ...
Authors:Hillen, H.S, Parshin, A.V, Agaronyan, K, Morozov, Y, Graber, J.J, Chernev, A, Schwinghammer, K, Urlaub, H, Anikin, M, Cramer, P, Temiakov, D.
Deposit date:2017-07-27
Release date:2017-10-18
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.904 Å)
Cite:Mechanism of Transcription Anti-termination in Human Mitochondria.
Cell, 171, 2017
8AD1
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BU of 8ad1 by Molmil
RNA polymerase at U-rich pause bound to RNA putL triple mutant - pause prone, closed clamp state
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Dey, S, Weixlbaumer, A.
Deposit date:2022-07-07
Release date:2022-10-19
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structural insights into RNA-mediated transcription regulation in bacteria.
Mol.Cell, 82, 2022
5GPC
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BU of 5gpc by Molmil
Structural analysis of fatty acid degradation regulator FadR from Bacillus halodurans
Descriptor: DNA (5'-D(P*CP*AP*TP*GP*AP*AP*TP*GP*AP*GP*TP*AP*TP*TP*CP*AP*TP*TP*CP*AP*T)-3'), DNA (5'-D(P*GP*AP*TP*GP*AP*AP*TP*GP*AP*AP*TP*AP*CP*TP*CP*AP*TP*TP*CP*AP*T)-3'), Transcriptional regulator (TetR/AcrR family)
Authors:Lee, J.Y, Yeo, H.K, Park, T.W.
Deposit date:2016-08-01
Release date:2017-03-01
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis of operator sites recognition and effector binding in the TetR family transcription regulator FadR.
Nucleic Acids Res., 45, 2017
1SMY
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BU of 1smy by Molmil
Structural basis for transcription regulation by alarmone ppGpp
Descriptor: DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ...
Authors:Artsimovitch, I, Patlan, V, Sekine, S, Vassylyeva, M.N, Hosaka, T, Ochi, K, Yokoyama, S, Vassylyev, D.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2004-03-10
Release date:2004-05-18
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis for transcription regulation by alarmone ppGpp
Cell(Cambridge,Mass.), 117, 2004
7OGR
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BU of 7ogr by Molmil
Structure of the apo-state of the bacteriophage PhiKZ non-virion RNA polymerase
Descriptor: DNA-directed RNA polymerase, PHIKZ055, PHIKZ068, ...
Authors:de Martin Garrido, N, Lai Wan Loong, Y.T.E, Yakunina, M, Aylett, C.H.S.
Deposit date:2021-05-07
Release date:2021-07-07
Last modified:2023-11-22
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structure of the bacteriophage PhiKZ non-virion RNA polymerase.
Nucleic Acids Res., 49, 2021
6FLQ
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BU of 6flq by Molmil
CryoEM structure of E.coli RNA polymerase paused elongation complex bound to NusA
Descriptor: DNA (31-MER), DNA (39-MER), DNA-directed RNA polymerase subunit alpha, ...
Authors:Guo, X, Weixlbaumer, A.
Deposit date:2018-01-26
Release date:2018-03-21
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural Basis for NusA Stabilized Transcriptional Pausing.
Mol. Cell, 69, 2018
5C4A
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BU of 5c4a by Molmil
Crystal structure of a transcribing RNA Polymerase II complex reveals a complete transcription bubble
Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
Authors:Barnes, C.O, Calero, M, Malik, I, Saphr, H, Zhang, Q, Pullara, F, Kaplan, C.D, Calero, G.
Deposit date:2015-06-17
Release date:2015-08-26
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (4.2 Å)
Cite:Crystal Structure of a Transcribing RNA Polymerase II Complex Reveals a Complete Transcription Bubble.
Mol.Cell, 59, 2015
5C4X
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BU of 5c4x by Molmil
Crystal structure of a transcribing RNA Polymerase II complex reveals a complete transcription bubble
Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
Authors:Barnes, C.O, Calero, M, Malik, I, Spahr, H, Zhang, Q, Pullara, F, Kaplan, C.D, Calero, G.
Deposit date:2015-06-18
Release date:2015-08-26
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (4 Å)
Cite:Crystal Structure of a Transcribing RNA Polymerase II Complex Reveals a Complete Transcription Bubble.
Mol.Cell, 59, 2015
6GML
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BU of 6gml by Molmil
Structure of paused transcription complex Pol II-DSIF-NELF
Descriptor: DNA-directed RNA polymerase II subunit RPB9, DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ...
Authors:Vos, S.M, Farnung, L, Urlaub, H, Cramer, P.
Deposit date:2018-05-27
Release date:2018-09-05
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structure of paused transcription complex Pol II-DSIF-NELF.
Nature, 560, 2018
5C44
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BU of 5c44 by Molmil
Crystal structure of a transcribing RNA Polymerase II complex reveals a complete transcription bubble
Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
Authors:Barnes, C.O, Calero, M, Malik, I, Spahr, H, Zhang, Q, Pullara, F, Kaplan, C.D, Calero, G.
Deposit date:2015-06-17
Release date:2015-08-26
Method:X-RAY DIFFRACTION (3.95 Å)
Cite:Crystal Structure of a Transcribing RNA Polymerase II Complex Reveals a Complete Transcription Bubble.
Mol.Cell, 59, 2015
6L8N
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BU of 6l8n by Molmil
Crystal structure of the K. lactis Rad5
Descriptor: DNA repair protein RAD5, ZINC ION
Authors:Shen, M, Xiang, S.
Deposit date:2019-11-06
Release date:2020-11-11
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Structural basis for the multi-activity factor Rad5 in replication stress tolerance.
Nat Commun, 12, 2021
8EVJ
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BU of 8evj by Molmil
CX3CR1 nucleosome bound PU.1 and C/EBPa
Descriptor: DNA (167-MER), Histone H2A type 2-C, Histone H2B type 2-E, ...
Authors:Guan, R, Bai, Y, Lian, T.
Deposit date:2022-10-20
Release date:2023-11-01
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structural mechanism of synergistic targeting of the CX3CR1 nucleosome by PU.1 and C/EBP alpha.
Nat.Struct.Mol.Biol., 31, 2024
8EVI
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BU of 8evi by Molmil
CX3CR1 nucleosome and PU.1 complex containing disulfide bond mutations
Descriptor: DNA (167-MER), Histone H2A type 2-C, Histone H2B type 2-E, ...
Authors:Lian, T, Guan, R, Bai, Y.
Deposit date:2022-10-20
Release date:2023-11-01
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (2.64 Å)
Cite:Structural mechanism of synergistic targeting of the CX3CR1 nucleosome by PU.1 and C/EBP alpha.
Nat.Struct.Mol.Biol., 31, 2024

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數據於2024-09-04公開中

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