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7AFV
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BU of 7afv by Molmil
Crystal structure of tetrameric beta-2-microglobulin deltaN6 S52C stabilized by a covalent ligand
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5-oxidanylidene-~{N}-(2-sulfanylethyl)-2,3-dihydro-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxamide, Beta-2-microglobulin
Authors:Guthertz, N, Cawood, E, Karamanos, T.
Deposit date:2020-09-20
Release date:2020-12-09
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Modulation of Amyloidogenic Protein Self-Assembly Using Tethered Small Molecules.
J.Am.Chem.Soc., 142, 2020
5DEN
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BU of 5den by Molmil
The First Structure of a Full-Length Mammalian Phenylalanine Hydroxylase Reveals the Architecture of an Auto-inhibited Tetramer
Descriptor: FE (III) ION, Phenylalanine-4-hydroxylase
Authors:Arturo, E.C, Loll, P.J, Jaffe, E.K.
Deposit date:2015-08-25
Release date:2016-02-17
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:First structure of full-length mammalian phenylalanine hydroxylase reveals the architecture of an autoinhibited tetramer.
Proc.Natl.Acad.Sci.USA, 113, 2016
3TNQ
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BU of 3tnq by Molmil
Structure and Allostery of the PKA RIIb Tetrameric Holoenzyme
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Protein kinase, ...
Authors:Zhang, P, Smith-Nguyen, E.V, Keshwani, M.M, Deal, M.S, Kornev, A.P, Taylor, S.S.
Deposit date:2011-09-01
Release date:2012-02-01
Last modified:2012-09-26
Method:X-RAY DIFFRACTION (3.097 Å)
Cite:Structure and allostery of the PKA RIIbeta tetrameric holoenzyme
Science, 335, 2012
6F2R
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BU of 6f2r by Molmil
A heterotetramer of human HspB2 and HspB3
Descriptor: Heat shock protein beta-2, Heat shock protein beta-3,Heat shock protein beta-3,Heat shock protein beta-3,Heat shock protein beta-3,Heat shock protein beta-2, HspB2,Heat shock protein beta-2,Heat shock protein beta-2,Heat shock protein beta-2,Heat shock protein beta-2,Heat shock protein beta-2, ...
Authors:Clark, A.R, Cole, A.R, Boelens, W.C, Keep, N.H, Slingsby, C.
Deposit date:2017-11-27
Release date:2018-07-25
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Terminal Regions Confer Plasticity to the Tetrameric Assembly of Human HspB2 and HspB3.
J.Mol.Biol., 430, 2018
6Q0X
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BU of 6q0x by Molmil
The cryo-EM structure of the SNX-BAR Mvp1 tetramer
Descriptor: Sorting nexin MVP1
Authors:Sun, D, Ford, M.G.J, Zhang, P.
Deposit date:2019-08-02
Release date:2020-04-01
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:The cryo-EM structure of the SNX-BAR Mvp1 tetramer.
Nat Commun, 11, 2020
1RIT
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BU of 1rit by Molmil
Crystal structure of Peanut lectin in complex with meso-tetrasulphonatophenylporphyrin and lactose
Descriptor: 5,10,15,20-TETRAKIS(4-SULPFONATOPHENYL)-21H,23H-PORPHINE, CALCIUM ION, Galactose-binding lectin, ...
Authors:Goel, M, Kaur, K.J, Maiya, B.G, Swamy, M.J, Salunke, D.M.
Deposit date:2003-11-17
Release date:2004-12-28
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Crystal structures of the PNA-porphyrin complex in the presence and absence of lactose: mapping the conformational changes on lactose binding, interacting surfaces, and supramolecular aggregations.
Biochemistry, 44, 2005
1RIR
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BU of 1rir by Molmil
Crystal structure of meso-tetrasulphonatophenylporphyrin in complex with Peanut lectin.
Descriptor: 5,10,15,20-TETRAKIS(4-SULPFONATOPHENYL)-21H,23H-PORPHINE, CALCIUM ION, Galactose-binding lectin, ...
Authors:Goel, M, Kaur, K.J, Maiya, B.G, Swamy, M.J, Salunke, D.M.
Deposit date:2003-11-17
Release date:2004-12-28
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structures of the PNA-porphyrin complex in the presence and absence of lactose: mapping the conformational changes on lactose binding, interacting surfaces, and supramolecular aggregations.
Biochemistry, 44, 2005
6TCL
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BU of 6tcl by Molmil
Photosystem I tetramer
Descriptor: 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, BETA-CAROTENE, ...
Authors:Chen, M, Perez-Boerema, A, Li, S, Amunts, A.
Deposit date:2019-11-06
Release date:2020-02-19
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Distinct structural modulation of photosystem I and lipid environment stabilizes its tetrameric assembly.
Nat.Plants, 6, 2020
3TNP
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BU of 3tnp by Molmil
Structure and Allostery of the PKA RIIb Tetrameric Holoenzyme
Descriptor: cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase type II-beta regulatory subunit
Authors:Zhang, P, Smith-Nguyen, E.V, Keshwani, M.M, Deal, M.S, Kornev, A.P, Taylor, S.S.
Deposit date:2011-09-01
Release date:2012-02-01
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure and allostery of the PKA RIIbeta tetrameric holoenzyme
Science, 335, 2012
8F73
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BU of 8f73 by Molmil
Crystal structure of Pseudomonas aeruginosa UDP-glucose phosphorylase in complex with UDP-glucose
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, MAGNESIUM ION, ...
Authors:Dirr, L, Fuehring, J.
Deposit date:2022-11-17
Release date:2023-11-29
Last modified:2024-06-12
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Tetramerization is essential for the enzymatic function of the Pseudomonas aeruginosa virulence factor UDP-glucose pyrophosphorylase.
Mbio, 15, 2024
5LQG
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BU of 5lqg by Molmil
A two-quartet G-quadruplex formed by human telomere in KCl solution at neutral pH
Descriptor: DNA (5'-D(*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*G)-3')
Authors:Galer, P, Wang, B, Sket, P, Plavec, J.
Deposit date:2016-08-17
Release date:2018-06-13
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Reversible pH Switch of Two-Quartet G-Quadruplexes Formed by Human Telomere.
Angew.Chem.Int.Ed.Engl., 55, 2016
5XLJ
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BU of 5xlj by Molmil
Crystal structure of the flagellar cap protein flid D2-D3 domains from serratia marcescens in Space group P432
Descriptor: CHLORIDE ION, Flagellar hook-associated protein 2, SODIUM ION
Authors:Cho, S.Y, Song, W.S, Hong, H.J, Yoon, S.I.
Deposit date:2017-05-10
Release date:2017-06-14
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Tetrameric structure of the flagellar cap protein FliD from Serratia marcescens.
Biochem. Biophys. Res. Commun., 489, 2017
5XLK
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BU of 5xlk by Molmil
Crystal structure of the flagellar cap protein FliD D2-D3 domains from Serratia marcescens in Space group I422
Descriptor: Flagellar hook-associated protein 2, ZINC ION
Authors:Cho, S.Y, Song, W.S, Hong, H.J, Yoon, S.I.
Deposit date:2017-05-10
Release date:2017-06-14
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Tetrameric structure of the flagellar cap protein FliD from Serratia marcescens.
Biochem. Biophys. Res. Commun., 489, 2017
5LQH
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BU of 5lqh by Molmil
A two-quartet G-quadruplex formed by human telomere in KCl solution at pH 5.0
Descriptor: DNA (5'-D(*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*G)-3')
Authors:Galer, P, Wang, B, Sket, P, Plavec, J.
Deposit date:2016-08-17
Release date:2018-01-17
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Reversible pH Switch of Two-Quartet G-Quadruplexes Formed by Human Telomere.
Angew.Chem.Int.Ed.Engl., 55, 2016
3EDC
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BU of 3edc by Molmil
Crystal Structure of a 1.6-hexanediol Bound Tetrameric Form of Escherichia coli Lac-repressor Refined to 2.1 Resolution
Descriptor: HEXANE-1,6-DIOL, Lactose operon repressor
Authors:Stenberg, K.A.E.
Deposit date:2008-09-03
Release date:2008-11-25
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of a 1.6-hexanediol bound tetrameric form of Escherichia coli lac-repressor refined to 2.1 A resolution
Proteins, 75, 2009
5WB6
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BU of 5wb6 by Molmil
FACTOR XIA IN COMPLEX WITH THE INHIBITOR methyl [(11S)-11-({(2E)-3-[5-chloro-2-(1H-tetrazol-1-yl)phenyl]prop-2-enoyl}amino)-6-fluoro-2-oxo-1,3,4,10,11,13-hexahydro-2H-5,9:15,12-di(azeno)-1,13-benzodiazacycloheptadecin-18-yl]carbamate
Descriptor: 1,2-ETHANEDIOL, Coagulation factor XI, SULFATE ION, ...
Authors:Sheriff, S.
Deposit date:2017-06-28
Release date:2017-08-02
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Macrocyclic factor XIa inhibitors.
Bioorg. Med. Chem. Lett., 27, 2017
4DFG
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BU of 4dfg by Molmil
Crystal Structure of Wild-type HIV-1 Protease with Cyclopentyltetrahydro- furanyl Urethanes as P2-ligand, GRL-0249A
Descriptor: CHLORIDE ION, Protease, SODIUM ION, ...
Authors:Wang, Y.-F, Agniswamy, J, Weber, I.T.
Deposit date:2012-01-23
Release date:2012-03-21
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.23 Å)
Cite:Substituent effects on P2-cyclopentyltetrahydrofuranyl urethanes: Design, synthesis, and X-ray studies of potent HIV-1 protease inhibitors.
Bioorg.Med.Chem.Lett., 22, 2012
2QIB
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BU of 2qib by Molmil
Crystal structure of tetR-family transcriptional regulator from Streptomyces coelicolor
Descriptor: HEXAETHYLENE GLYCOL, tetR-family transcriptional regulator
Authors:Zhang, R, Xu, X, Zheng, H, Savchenko, A, Edwards, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2007-07-03
Release date:2007-09-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The crystal structure of tetR-family transcriptional regulator from Streptomyces coelicolor.
To be Published
3KTX
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BU of 3ktx by Molmil
Crystal structure of Leishmania mexicana pyruvate kinase (LmPYK)in complex with 1,3,6,8-pyrenetetrasulfonic acid
Descriptor: GLYCEROL, Pyruvate kinase, pyrene-1,3,6,8-tetrasulfonic acid
Authors:Morgan, H.P, Walkinshaw, M.D.
Deposit date:2009-11-26
Release date:2010-02-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:An improved strategy for the crystallization of Leishmania mexicana pyruvate kinase.
Acta Crystallogr.,Sect.F, 66, 2010
5X1N
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BU of 5x1n by Molmil
Vanillate/3-O-methylgallate O-demethylase, LigM, protocatechuate-tetrahydrofolate complex form
Descriptor: (6S)-5,6,7,8-TETRAHYDROFOLATE, 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ...
Authors:Harada, A, Senda, T.
Deposit date:2017-01-26
Release date:2017-05-17
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:The crystal structure of a new O-demethylase from Sphingobium sp. strain SYK-6
FEBS J., 284, 2017
1VZJ
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BU of 1vzj by Molmil
Structure of the tetramerization domain of acetylcholinesterase: four-fold interaction of a WWW motif with a left-handed polyproline helix
Descriptor: ACETYLCHOLINESTERASE, ACETYLCHOLINESTERASE COLLAGENIC TAIL PEPTIDE
Authors:Dvir, H, Harel, M, Bon, S, Liu, W.-Q, Vidal, M, Garbay, C, Sussman, J.L, Massoulie, J, Silman, I.
Deposit date:2004-05-20
Release date:2005-01-10
Last modified:2019-10-16
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:The Synaptic Acetylcholinesterase Tetramer Assembles Around a Polyproline-II Helix
Embo J., 23, 2004
3KXM
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BU of 3kxm by Molmil
Crystal structure of Z. mays CK2 kinase alpha subunit in complex with the inhibitor K74
Descriptor: Casein kinase II subunit alpha, N-methyl-2-[(4,5,6,7-tetrabromo-1-methyl-1H-benzimidazol-2-yl)sulfanyl]acetamide
Authors:Papinutto, E, Franchin, C, Battistutta, R.
Deposit date:2009-12-03
Release date:2010-11-17
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:ATP site-directed inhibitors of protein kinase CK2: an update.
Curr Top Med Chem, 11, 2011
2J0Z
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BU of 2j0z by Molmil
p53 tetramerization domain wild type
Descriptor: CELLULAR TUMOR ANTIGEN P53
Authors:Carbajo, R.J, Mora, P, Sanchez del Pino, M.M, Perez-Paya, E, Pineda-Lucena, A.
Deposit date:2006-08-08
Release date:2007-08-28
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Solvent-exposed residues located in the beta-sheet modulate the stability of the tetramerization domain of p53--a structural and combinatorial approach.
Proteins, 71, 2008
2J10
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BU of 2j10 by Molmil
p53 tetramerization domain mutant T329F Q331K
Descriptor: CELLULAR TUMOR ANTIGEN P53
Authors:Carbajo, R.J, Mora, P, Sanchez del Pino, M.M, Perez-Paya, E, Pineda-Lucena, A.
Deposit date:2006-08-08
Release date:2007-08-28
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Solvent-exposed residues located in the beta-sheet modulate the stability of the tetramerization domain of p53--a structural and combinatorial approach.
Proteins, 71, 2008
4YZY
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BU of 4yzy by Molmil
Crystal structures reveal transient PERK luminal domain tetramerization in ER stress signaling
Descriptor: Eukaryotic translation initiation factor 2-alpha kinase 3
Authors:Carrara, M, Prischi, F, Ali, M.M.U.
Deposit date:2015-03-25
Release date:2015-05-13
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structures reveal transient PERK luminal domain tetramerization in endoplasmic reticulum stress signaling.
Embo J., 34, 2015

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數據於2024-10-09公開中

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