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2FEJ
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BU of 2fej by Molmil
Solution structure of human p53 DNA binding domain.
Descriptor: Cellular tumor antigen p53, ZINC ION
Authors:Perez-Canadillas, J.M, Tidow, H, Freund, S.M, Rutherford, T.J, Ang, H.C, Fersht, A.R.
Deposit date:2005-12-16
Release date:2006-01-31
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of p53 core domain: Structural basis for its instability
Proc.Natl.Acad.Sci.Usa, 103, 2006
3KLN
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BU of 3kln by Molmil
Vibrio cholerae VpsT
Descriptor: Transcriptional regulator, LuxR family
Authors:Krasteva, P.V, Navarro, V.A.S, Sondermann, H.
Deposit date:2009-11-08
Release date:2010-02-09
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.078 Å)
Cite:Vibrio cholerae VpsT Regulates Matrix Production and Motility by Directly Sensing Cyclic di-GMP.
Science, 327, 2010
7CKK
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BU of 7ckk by Molmil
Structural complex of FTO bound with Dac51
Descriptor: 2-{[2,6-dichloro-4-(3,5-dimethyl-1H-pyrazol-4-yl)phenyl]amino}-N-hydroxybenzamide, Alpha-ketoglutarate-dependent dioxygenase FTO, N-OXALYLGLYCINE
Authors:Yang, C, Gan, J.
Deposit date:2020-07-17
Release date:2021-07-21
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Tumors exploit FTO-mediated regulation of glycolytic metabolism to evade immune surveillance.
Cell Metab., 33, 2021
3KLO
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BU of 3klo by Molmil
Vibrio cholerae VpsT bound to c-di-GMP
Descriptor: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), D(-)-TARTARIC ACID, Transcriptional regulator VpsT
Authors:Krasteva, P.V, Navarro, V.A.S, Sondermann, H.
Deposit date:2009-11-08
Release date:2010-02-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.802 Å)
Cite:Vibrio cholerae VpsT Regulates Matrix Production and Motility by Directly Sensing Cyclic di-GMP.
Science, 327, 2010
6JY1
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BU of 6jy1 by Molmil
Crystal Structure of a Group II pyridoxal dependent decarboxylase, LLP-bound form from Methanocaldococcus jannaschii at 1.72 A
Descriptor: GLYCEROL, L-tyrosine/L-aspartate decarboxylase, SULFATE ION
Authors:Manoj, N, Gayathri, S.C.
Deposit date:2019-04-25
Release date:2019-10-30
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Structural insights into the mechanism of internal aldimine formation and catalytic loop dynamics in an archaeal Group II decarboxylase.
J.Struct.Biol., 208, 2019
3LVH
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BU of 3lvh by Molmil
Crystal structure of a clathrin heavy chain and clathrin light chain complex
Descriptor: Clathrin heavy chain 1, Clathrin light chain B
Authors:Wilbur, J.D, Hwang, P.K, Ybe, J.A, Lane, M, Sellers, B.D, Jacobson, M.P, Fletterick, R.J, Brodsky, F.M.
Deposit date:2010-02-20
Release date:2010-06-09
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (9 Å)
Cite:Conformation switching of clathrin light chain regulates clathrin lattice assembly.
Dev.Cell, 18, 2010
5DYM
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BU of 5dym by Molmil
Crystal structure of a PadR family transcription regulator from hypervirulent Clostridium difficile R20291 - CdPadR_0991 to 1.89 Angstrom resolution
Descriptor: PadR-family transcriptional regulator
Authors:Isom, C.E, Karr, E.A, Menon, S.K, West, A.H, Richter-Addo, G.B.
Deposit date:2015-09-24
Release date:2016-10-05
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.894 Å)
Cite:Crystal structure and DNA binding activity of a PadR family transcription regulator from hypervirulent Clostridium difficile R20291.
Bmc Microbiol., 16, 2016
5BRJ
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BU of 5brj by Molmil
Structure of the bacteriophytochrome response regulator AtBRR
Descriptor: MAGNESIUM ION, Two component response regulator
Authors:Baker, A.W, Satyshur, K.A, Forest, K.T.
Deposit date:2015-05-31
Release date:2016-02-24
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.922 Å)
Cite:Arm-in-Arm Response Regulator Dimers Promote Intermolecular Signal Transduction.
J.Bacteriol., 198, 2016
6K8E
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BU of 6k8e by Molmil
Global regulatory element SarX
Descriptor: HTH-type transcriptional regulator SarX
Authors:Wang, Q.
Deposit date:2019-06-11
Release date:2020-06-17
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.002 Å)
Cite:Crystal structure of SarX from Staphylococcus aureus
To Be Published
2RD8
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BU of 2rd8 by Molmil
Human Thymidylate Synthase Stabilized in Active Conformation by R163K Mutation: Asymmetry and Reactivity of Cys195
Descriptor: BETA-MERCAPTOETHANOL, PHOSPHATE ION, Thymidylate synthase
Authors:Gibson, L.M, Lovelace, L.L, Lebioda, L.
Deposit date:2007-09-21
Release date:2008-05-27
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The R163K Mutant of Human Thymidylate Synthase Is Stabilized in an Active Conformation: Structural Asymmetry and Reactivity of Cysteine 195.
Biochemistry, 47, 2008
7TU0
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BU of 7tu0 by Molmil
Structure of the L. blandensis dGTPase bound to Mn
Descriptor: MANGANESE (II) ION, SULFATE ION, dGTP triphosphohydrolase
Authors:Sikkema, A.P, Klemm, B.P, Horng, J.C, Hall, T.M.T.
Deposit date:2022-02-02
Release date:2022-06-01
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:High-resolution structures of the SAMHD1 dGTPase homolog from Leeuwenhoekiella blandensis reveal a novel mechanism of allosteric activation by dATP.
J.Biol.Chem., 298, 2022
7TU1
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BU of 7tu1 by Molmil
Structure of the L. blandensis dGTPase R37A mutant
Descriptor: 1,2-ETHANEDIOL, SULFATE ION, dGTP triphosphohydrolase
Authors:Sikkema, A.P, Klemm, B.P, Horng, J.C, Hall, T.M.T.
Deposit date:2022-02-02
Release date:2022-06-01
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:High-resolution structures of the SAMHD1 dGTPase homolog from Leeuwenhoekiella blandensis reveal a novel mechanism of allosteric activation by dATP.
J.Biol.Chem., 298, 2022
7TU2
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BU of 7tu2 by Molmil
Structure of the L. blandensis dGTPase R37A mutant bound to Mn
Descriptor: MANGANESE (II) ION, SULFATE ION, dGTP triphosphohydrolase
Authors:Sikkema, A.P, Klemm, B.P, Horng, J.C, Hall, T.M.T.
Deposit date:2022-02-02
Release date:2022-06-01
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:High-resolution structures of the SAMHD1 dGTPase homolog from Leeuwenhoekiella blandensis reveal a novel mechanism of allosteric activation by dATP.
J.Biol.Chem., 298, 2022
7TU3
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BU of 7tu3 by Molmil
Structure of the L. blandensis dGTPase del55-58 mutant
Descriptor: 1,2-ETHANEDIOL, MAGNESIUM ION, SULFATE ION, ...
Authors:Sikkema, A.P, Klemm, B.P, Horng, J.C, Hall, T.M.T.
Deposit date:2022-02-02
Release date:2022-06-01
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:High-resolution structures of the SAMHD1 dGTPase homolog from Leeuwenhoekiella blandensis reveal a novel mechanism of allosteric activation by dATP.
J.Biol.Chem., 298, 2022
7TU4
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BU of 7tu4 by Molmil
Structure of the L. blandensis dGTPase del55-58 mutant bound to Mn
Descriptor: 1,2-ETHANEDIOL, MANGANESE (II) ION, SULFATE ION, ...
Authors:Sikkema, A.P, Klemm, B.P, Horng, J.C, Hall, T.M.T.
Deposit date:2022-02-02
Release date:2022-06-01
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:High-resolution structures of the SAMHD1 dGTPase homolog from Leeuwenhoekiella blandensis reveal a novel mechanism of allosteric activation by dATP.
J.Biol.Chem., 298, 2022
7CFK
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BU of 7cfk by Molmil
Structure of the CBS domain of the bacterial CNNM/CorC family Mg2+ transporter in complex with the novel inhibitor IGN95a
Descriptor: (2S)-2-[(6-azanyl-9H-purin-8-yl)sulfanyl]butanoic acid, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Hemolysin
Authors:Huang, Y, Jin, F, Hattori, M.
Deposit date:2020-06-25
Release date:2021-04-21
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Identification and mechanistic analysis of an inhibitor of the CorC Mg 2+ transporter.
Iscience, 24, 2021
2CJ6
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BU of 2cj6 by Molmil
Crystal Structure of a Cell Wall Invertase Inhibitor from Tobacco (pH 7.5)
Descriptor: INVERTASE INHIBITOR, IODIDE ION
Authors:Hothorn, M, Scheffzek, K.
Deposit date:2006-03-29
Release date:2006-03-30
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Multiple Crystal Forms of the Cell-Wall Invertase Inhibitor from Tobacco Support High Conformational Rigidity Over a Broad Ph-Range
Acta Crystallogr.,Sect.D, 62, 2006
2CJ4
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BU of 2cj4 by Molmil
Crystal Structure of a Cell Wall Invertase Inhibitor from Tobacco at pH 4.6
Descriptor: ACETATE ION, INVERTASE INHIBITOR, SULFATE ION
Authors:Hothorn, M, Scheffzek, K.
Deposit date:2006-03-29
Release date:2006-03-30
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Multiple Crystal Forms of the Cell Wall Invertase Inhibitor from Tobacco Support High Conformational Rigidity Over a Broad Ph-Range
Acta Crystallogr.,Sect.D, 62, 2006
2CJ7
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BU of 2cj7 by Molmil
Crystal Structure of a Cell Wall Invertase Inhibitor from Tobacco (pH 9.0)
Descriptor: INVERTASE INHIBITOR, IODIDE ION
Authors:Hothorn, M, Scheffzek, K.
Deposit date:2006-03-29
Release date:2006-04-03
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Multiple Crystal Forms of the Cell-Wall Invertase Inhibitor from Tobacco Support High Conformational Rigidity Over a Broad Ph-Range
Acta Crystallogr.,Sect.D, 62, 2006
4MA9
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BU of 4ma9 by Molmil
Wild type Salmonella Alkyl Hydroperoxide Reductase C in its substrate-ready conformation
Descriptor: Alkyl hydroperoxide reductase subunit C, CHLORIDE ION, GLYCEROL, ...
Authors:Perkins, A, Karplus, P.A.
Deposit date:2013-08-15
Release date:2013-11-20
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:The sensitive balance between the fully folded and locally unfolded conformations of a model peroxiredoxin.
Biochemistry, 52, 2013
7RMW
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BU of 7rmw by Molmil
Crystal structure of B. subtilis PurR bound to ppGpp
Descriptor: GUANOSINE-5',3'-TETRAPHOSPHATE, Pur operon repressor
Authors:Schumacher, M.A.
Deposit date:2021-07-28
Release date:2021-12-22
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:The nucleotide messenger (p)ppGpp is an anti-inducer of the purine synthesis transcription regulator PurR in Bacillus.
Nucleic Acids Res., 50, 2022
2CJ5
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BU of 2cj5 by Molmil
Crystal Structure of a Cell Wall Invertase Inhibitor from Tobacco (pH 5.0)
Descriptor: ACETATE ION, INVERTASE INHIBITOR, SULFATE ION
Authors:Hothorn, M, Scheffzek, K.
Deposit date:2006-03-29
Release date:2006-03-30
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Multiple Crystal Forms of the Cell-Wall Invertase Inhibitor from Tobacco Support High Conformational Rigidity Over a Broad Ph-Range
Acta Crystallogr.,Sect.D, 62, 2006
2CJ8
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BU of 2cj8 by Molmil
Crystal Structure of a Cell Wall Invertase Inhibitor from Tobacco (pH 9.5)
Descriptor: INVERTASE INHIBITOR, IODIDE ION
Authors:Hothorn, M, Scheffzek, K.
Deposit date:2006-03-29
Release date:2006-04-03
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Multiple Crystal Forms of the Cell-Wall Invertase Inhibitor from Tobacco Support High Conformational Rigidity Over a Broad Ph-Range
Acta Crystallogr.,Sect.D, 62, 2006
3IAU
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BU of 3iau by Molmil
The structure of the processed form of threonine deaminase isoform 2 from Solanum lycopersicum
Descriptor: ACETATE ION, POLYETHYLENE GLYCOL (N=34), SULFATE ION, ...
Authors:Bianchetti, C.M, Bingman, C.A, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG)
Deposit date:2009-07-14
Release date:2009-07-28
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.353 Å)
Cite:Adaptive evolution of threonine deaminase in plant defense against insect herbivores.
Proc.Natl.Acad.Sci.USA, 108, 2011
5DGH
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BU of 5dgh by Molmil
Crystal structure of the catalytic domain of human diphosphoinositol pentakisphosphate kinase 2 (PPIP5K2) in complex with AMP-PNP and 5-(PCP)-IP5
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2, ...
Authors:Wang, H, Shears, S.B.
Deposit date:2015-08-27
Release date:2016-08-10
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Cellular Cations Control Conformational Switching of Inositol Pyrophosphate Analogues.
Chemistry, 22, 2016

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數據於2024-09-11公開中

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