5DGH
Crystal structure of the catalytic domain of human diphosphoinositol pentakisphosphate kinase 2 (PPIP5K2) in complex with AMP-PNP and 5-(PCP)-IP5
Summary for 5DGH
| Entry DOI | 10.2210/pdb5dgh/pdb |
| Related | 5DGI |
| Descriptor | Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Methylenebisphosphonate inositol pentakisphosphate, ... (7 entities in total) |
| Functional Keywords | transferase inositol diphosphoinositol pentakisphosphate kinase analog methylenebisphosphonate ppip5k atp-grasp pyrophosphate diphosphate, transferase |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 1 |
| Total formula weight | 39425.15 |
| Authors | Wang, H.,Shears, S.B. (deposition date: 2015-08-27, release date: 2016-08-10, Last modification date: 2023-09-27) |
| Primary citation | Hager, A.,Wu, M.,Wang, H.,Brown, N.W.,Shears, S.B.,Veiga, N.,Fiedler, D. Cellular Cations Control Conformational Switching of Inositol Pyrophosphate Analogues. Chemistry, 22:12406-12414, 2016 Cited by PubMed: 27460418DOI: 10.1002/chem.201601754 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
Download full validation report
