7TU2
Structure of the L. blandensis dGTPase R37A mutant bound to Mn
Summary for 7TU2
Entry DOI | 10.2210/pdb7tu2/pdb |
Descriptor | dGTP triphosphohydrolase, SULFATE ION, MANGANESE (II) ION, ... (4 entities in total) |
Functional Keywords | dgtpase, nucleotide binding, hydrolase |
Biological source | Leeuwenhoekiella blandensis |
Total number of polymer chains | 3 |
Total formula weight | 158364.38 |
Authors | Sikkema, A.P.,Klemm, B.P.,Horng, J.C.,Hall, T.M.T. (deposition date: 2022-02-02, release date: 2022-06-01, Last modification date: 2023-10-18) |
Primary citation | Klemm, B.P.,Sikkema, A.P.,Hsu, A.L.,Horng, J.C.,Hall, T.M.T.,Borgnia, M.J.,Schaaper, R.M. High-resolution structures of the SAMHD1 dGTPase homolog from Leeuwenhoekiella blandensis reveal a novel mechanism of allosteric activation by dATP. J.Biol.Chem., 298:102073-102073, 2022 Cited by PubMed: 35643313DOI: 10.1016/j.jbc.2022.102073 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.13 Å) |
Structure validation
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