4P9R
 
 | | Speciation of a group I intron into a lariat capping ribozyme (Heavy atom derivative) | | Descriptor: | IRIDIUM HEXAMMINE ION, MAGNESIUM ION, RNA (189-MER) | | Authors: | Meyer, M, Nielsen, H, Olieric, V, Roblin, P, Johansen, S.D, Westhof, E, Masquida, B. | | Deposit date: | 2014-04-04 | | Release date: | 2014-05-28 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.703 Å) | | Cite: | Speciation of a group I intron into a lariat capping ribozyme.
Proc.Natl.Acad.Sci.USA, 111, 2014
|
|
2QUD
 | | PP7 Coat Protein Dimer | | Descriptor: | Coat protein, GLYCEROL | | Authors: | Chao, J.A. | | Deposit date: | 2007-08-04 | | Release date: | 2007-12-18 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structural basis for the coevolution of a viral RNA-protein complex.
Nat.Struct.Mol.Biol., 15, 2008
|
|
4MFR
 | | Crystal structure of Mycobacterium tuberculosis CarD | | Descriptor: | GLYCEROL, IODIDE ION, RNA polymerase-binding transcription factor CarD, ... | | Authors: | Kaur, G, Thakur, K.G. | | Deposit date: | 2013-08-28 | | Release date: | 2013-11-06 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structure of Mycobacterium tuberculosis CarD, an essential RNA polymerase binding protein, reveals a quasidomain-swapped dimeric structural architecture.
Proteins, 82, 2014
|
|
2HOK
 | |
2HOM
 | |
6FSO
 | | Crystal Structure of TGT in complex with methyl({[5-(pyridin-3-yloxy)furan-2-yl]methyl})amine | | Descriptor: | ACETATE ION, DI(HYDROXYETHYL)ETHER, DIMETHYL SULFOXIDE, ... | | Authors: | Hassaan, E, Heine, A, Klebe, G. | | Deposit date: | 2018-02-20 | | Release date: | 2019-03-20 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.449 Å) | | Cite: | Fragments as Novel Starting Points for tRNA-Guanine Transglycosylase Inhibitors Found by Alternative Screening Strategies.
Chemmedchem, 15, 2020
|
|
4DQ7
 | |
4DHX
 | | ENY2:GANP complex | | Descriptor: | 80 kDa MCM3-associated protein, Enhancer of yellow 2 transcription factor homolog | | Authors: | Stewart, M, Jani, D. | | Deposit date: | 2012-01-30 | | Release date: | 2012-06-13 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Functional and structural characterization of the mammalian TREX-2 complex that links transcription with nuclear messenger RNA export.
Nucleic Acids Res., 40, 2012
|
|
7XRC
 | |
4DQ5
 | | Structural Investigation of Bacteriophage Phi6 Lysin (WT) | | Descriptor: | 4-(2-AMINOETHYL)BENZENESULFONYL FLUORIDE, Membrane protein Phi6 P5wt | | Authors: | Dessau, M.A, Modis, Y. | | Deposit date: | 2012-02-15 | | Release date: | 2013-01-02 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.395 Å) | | Cite: | Selective pressure causes an RNA virus to trade reproductive fitness for increased structural and thermal stability of a viral enzyme.
PLoS Genet, 8, 2012
|
|
4DQJ
 | | Structural Investigation of Bacteriophage Phi6 Lysin (in complex with chitotetraose) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-AMINOETHYL)BENZENESULFONYL FLUORIDE, Membrane protein Phi6 P5 | | Authors: | Dessau, M.A, Modis, Y. | | Deposit date: | 2012-02-16 | | Release date: | 2013-01-02 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.23 Å) | | Cite: | Selective pressure causes an RNA virus to trade reproductive fitness for increased structural and thermal stability of a viral enzyme.
PLoS Genet, 8, 2012
|
|
3HR3
 | |
5VM7
 | | Pseudo-atomic model of the MurA-A2 complex | | Descriptor: | Maturation protein A2, UDP-N-acetylglucosamine 1-carboxyvinyltransferase | | Authors: | Cui, Z, Zhang, J. | | Deposit date: | 2017-04-26 | | Release date: | 2017-10-18 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (5.7 Å) | | Cite: | Structures of Q beta virions, virus-like particles, and the Q beta-MurA complex reveal internal coat proteins and the mechanism of host lysis.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
|
|
4K7H
 | | Major capsid protein P1 of the Pseudomonas phage phi6 | | Descriptor: | Major inner protein P1 | | Authors: | Boura, E, Nemecek, D, Plevka, P, Steven, C.A, Hurley, J.H. | | Deposit date: | 2013-04-17 | | Release date: | 2013-08-14 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (3.5964 Å) | | Cite: | Subunit Folds and Maturation Pathway of a dsRNA Virus Capsid.
Structure, 21, 2013
|
|
1TQL
 | | POLIOVIRUS POLYMERASE G1A MUTANT | | Descriptor: | ACETIC ACID, RNA-directed RNA polymerase | | Authors: | Thompson, A.A, Peersen, O.B. | | Deposit date: | 2004-06-17 | | Release date: | 2004-08-17 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural basis for proteolysis-dependent activation of the poliovirus RNA-dependent RNA polymerase
Embo J., 23, 2004
|
|
2YTZ
 | | Complex structure of Trm1 from Pyrococcus horikoshii with S-adenosyl-L-Homocystein in the orthorhombic crystal-lattice | | Descriptor: | N(2),N(2)-dimethylguanosine tRNA methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION | | Authors: | Ihsanawati, Shirouzu, M, Bessho, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2007-04-05 | | Release date: | 2007-10-09 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | Crystal Structure of tRNA N(2),N(2)-Guanosine Dimethyltransferase Trm1 from Pyrococcus horikoshii
J.Mol.Biol., 383, 2008
|
|
7EDC
 | | Crystal structure of mutant tRNA [Gm18] methyltransferase TrmH (E107G) in complex with S-adenosyl-L-methionine from Escherichia coli | | Descriptor: | PHOSPHATE ION, S-ADENOSYLMETHIONINE, tRNA (guanosine(18)-2'-O)-methyltransferase | | Authors: | Kono, Y, Ito, A, Okamoto, A, Yamagami, R, Hirata, A, Hori, H. | | Deposit date: | 2021-03-15 | | Release date: | 2022-03-23 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (1.946 Å) | | Cite: | Unique substrate specificity of type II tRNA Gm18 methyltransferase from Escherichia coli
To Be Published
|
|
1U2F
 | | SOLUTION STRUCTURE OF THE FIRST RNA-BINDING DOMAIN OF HU2AF65 | | Descriptor: | PROTEIN (SPLICING FACTOR U2AF 65 KD SUBUNIT) | | Authors: | Ito, T, Muto, Y, Green, M.R, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 1999-05-26 | | Release date: | 1999-08-20 | | Last modified: | 2023-12-27 | | Method: | SOLUTION NMR | | Cite: | Solution structures of the first and second RNA-binding domains of human U2 small nuclear ribonucleoprotein particle auxiliary factor (U2AF(65)).
EMBO J., 18, 1999
|
|
2J7W
 | | Dengue virus NS5 RNA dependent RNA polymerase domain complexed with 3' dGTP | | Descriptor: | DI(HYDROXYETHYL)ETHER, GUANOSINE-5'-TRIPHOSPHATE, POLYPROTEIN, ... | | Authors: | Yap, T.L, Xu, T, Chen, Y.L, Malet, H, Egloff, M.P, Canard, B, Vasudevan, S.G, Lescar, J. | | Deposit date: | 2006-10-17 | | Release date: | 2007-03-13 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Crystal Structure of the Dengue Virus RNA- Dependent RNA Polymerase Catalytic Domain at 1.85 Angstrom Resolution.
J.Virol., 81, 2007
|
|
7U8B
 | | Product of 14mer primer with activated asymmetric GA dimer diastereomer 1 | | Descriptor: | 5'-O-[(S)-(2-amino-1H-imidazol-1-yl)(hydroxy)phosphoryl]adenosine, RNA (5'-R(*(TLN)P*(LCC)P*(LCC)P*(LCG)P*AP*CP*UP*UP*AP*AP*GP*UP*CP*GP*(G46))-3'), SULFATE ION | | Authors: | Fang, Z, Szostak, J.W. | | Deposit date: | 2022-03-08 | | Release date: | 2023-03-15 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.73 Å) | | Cite: | Understanding the metal ion function in the RNA non-enzymatic extesion with phosphorothioates
To Be Published
|
|
4BTG
 | | Coordinates of the bacteriophage phi6 capsid subunits (P1A and P1B) fitted into the cryoEM reconstruction of the procapsid at 4.4 A resolution | | Descriptor: | MAJOR INNER PROTEIN P1 | | Authors: | Nemecek, D, Boura, E, Wu, W, Cheng, N, Plevka, P, Qiao, J, Mindich, L, Heymann, J.B, Hurley, J.H, Steven, A.C. | | Deposit date: | 2013-06-17 | | Release date: | 2013-08-14 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (4.4 Å) | | Cite: | Subunit Folds and Maturation Pathway of a Dsrna Virus Capsid.
Structure, 21, 2013
|
|
5ZYO
 | |
8C3G
 | | Crystal structure of DYRK1A in complex with AZ191 | | Descriptor: | 1,2-ETHANEDIOL, Dual specificity tyrosine-phosphorylation-regulated kinase 1A, N-[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]-4-(1-methylpyrrolo[2,3-c]pyridin-3-yl)pyrimidin-2-amine, ... | | Authors: | Grygier, P, Pustelny, K, Dubin, G, Czarna, A. | | Deposit date: | 2022-12-23 | | Release date: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.08 Å) | | Cite: | Structural perspective on the design of selective DYRK1B inhibitors
To Be Published
|
|
8C3Q
 | |
8C3R
 | |
