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3HR3

Interplay of Structure, Hydration and Thermal Stability in Formacetal Modified Oligonucleotides: RNA May Tolerate Hydrophobic Modifications Better than DNA

Summary for 3HR3
Entry DOI10.2210/pdb3hr3/pdb
Descriptor5'-D(*GP*CP*GP*(US4)P*(OMU))P*AP*CP*GP*C)-3' (2 entities in total)
Functional Keywordsdna, rna, formacetal-dna, rna hydration
Total number of polymer chains1
Total formula weight3011.05
Authors
Egli, M.,Pallan, P.S. (deposition date: 2009-06-08, release date: 2009-10-27, Last modification date: 2023-09-06)
Primary citationKolarovic, A.,Schweizer, E.,Greene, E.,Gironda, M.,Pallan, P.S.,Egli, M.,Rozners, E.
Interplay of structure, hydration and thermal stability in formacetal modified oligonucleotides: RNA may tolerate nonionic modifications better than DNA.
J.Am.Chem.Soc., 131:14932-14937, 2009
Cited by
PubMed: 19824732
DOI: 10.1021/ja904926e
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.75 Å)
Structure validation

217705

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