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8IK0
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BU of 8ik0 by Molmil
Cryo-EM structure of Stimulator of interferon genes
Descriptor: Stimulator of interferon genes protein,Immune protein Tsi3
Authors:Lu, D.F, Shang, G.J.
Deposit date:2023-02-28
Release date:2023-05-17
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:The mechanism of STING autoinhibition and activation.
Mol.Cell, 83, 2023
2MCX
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BU of 2mcx by Molmil
Solid-state NMR structure of piscidin 3 in aligned 1:1 phosphatidylethanolamine/phosphoglycerol lipid bilayers
Descriptor: Piscidin-3
Authors:Fu, R, Tian, Y, Perrin Jr, B.S, Grant, C.V, Wieczorek, W.E, Pastor, R.W, Cotten, M.L.
Deposit date:2013-08-27
Release date:2014-01-22
Last modified:2021-08-18
Method:SOLID-STATE NMR
Cite:High-resolution structures and orientations of antimicrobial peptides piscidin 1 and piscidin 3 in fluid bilayers reveal tilting, kinking, and bilayer immersion.
J.Am.Chem.Soc., 136, 2014
3PY6
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BU of 3py6 by Molmil
Crystal Structure of a Beta-Lactamase-Like Protein from Brucella Melitensis bound to GMP
Descriptor: Beta-lactamase-like, D(-)-TARTARIC ACID, GUANOSINE-5'-MONOPHOSPHATE, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2010-12-11
Release date:2010-12-22
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal Structure of a Beta-Lactamase-Like Protein from Brucella Melitensis bound to GMP
Acta Crystallogr.,Sect.F, 67, 2011
2MJS
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BU of 2mjs by Molmil
Anoplin R5K T8W in DPC micelles
Descriptor: Anoplin, UNKNOWN ATOM OR ION, dodecyl 2-(trimethylammonio)ethyl phosphate
Authors:Uggerhoej, L, Poulsen, T.J, Wimmer, R.
Deposit date:2014-01-16
Release date:2014-12-03
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Rational Design of Alpha-Helical Antimicrobial Peptides: Do's and Don'ts.
Chembiochem, 16, 2015
2MCW
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BU of 2mcw by Molmil
Solid-state NMR structure of piscidin 3 in aligned 3:1 phosphatidylcholine/phosphoglycerol lipid bilayers
Descriptor: Piscidin-3
Authors:Fu, R, Tian, Y, Perrin Jr, B.S, Grant, C.V, Pastor, R.W, Cotten, M.L.
Deposit date:2013-08-27
Release date:2014-01-22
Last modified:2014-03-19
Method:SOLID-STATE NMR
Cite:High-resolution structures and orientations of antimicrobial peptides piscidin 1 and piscidin 3 in fluid bilayers reveal tilting, kinking, and bilayer immersion.
J.Am.Chem.Soc., 136, 2014
2MCV
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BU of 2mcv by Molmil
Solid-state NMR structure of piscidin 1 in aligned 1:1 phosphatidylethanolamine/phosphoglycerol lipid bilayers
Descriptor: Moronecidin
Authors:Fu, R, Tian, Y, Perrin Jr, B.S, Grant, C.V, Hayden, R.M, Pastor, R.W, Cotten, M.L.
Deposit date:2013-08-27
Release date:2014-01-22
Last modified:2014-03-19
Method:SOLID-STATE NMR
Cite:High-resolution structures and orientations of antimicrobial peptides piscidin 1 and piscidin 3 in fluid bilayers reveal tilting, kinking, and bilayer immersion.
J.Am.Chem.Soc., 136, 2014
7KR3
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BU of 7kr3 by Molmil
Human DNA Ligase 1(E346A/E592A) Bound to a bulged DNA substrate
Descriptor: ACETATE ION, ADENOSINE MONOPHOSPHATE, DNA (5'-D(*AP*AP*TP*GP*TP*CP*TP*GP*CP*CP*CP*C)-3'), ...
Authors:Tumbale, P.P, Williams, R.S.
Deposit date:2020-11-18
Release date:2021-02-03
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.778 Å)
Cite:High-fidelity DNA ligation enforces accurate Okazaki fragment maturation during DNA replication.
Nat Commun, 12, 2021
7L34
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BU of 7l34 by Molmil
Human DNA Ligase 1 - R641L nicked DNA complex
Descriptor: ADENOSINE MONOPHOSPHATE, DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*TP*C)-3'), DNA (5'-D(*GP*TP*CP*CP*GP*AP*CP*GP*AP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ...
Authors:Tumbale, P.P, Williams, R.S, Schellenberg, M.S.
Deposit date:2020-12-17
Release date:2021-01-13
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.901 Å)
Cite:LIG1 syndrome mutations remodel a cooperative network of ligand binding interactions to compromise ligation efficiency.
Nucleic Acids Res., 49, 2021
2MJR
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BU of 2mjr by Molmil
Anoplin R5W structure in DPC micelles
Descriptor: Anoplin, UNKNOWN ATOM OR ION, dodecyl 2-(trimethylammonio)ethyl phosphate
Authors:Uggerhoej, L, Poulsen, T.J, Wimmer, R.
Deposit date:2014-01-16
Release date:2014-12-03
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Rational Design of Alpha-Helical Antimicrobial Peptides: Do's and Don'ts.
Chembiochem, 16, 2015
2MJQ
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BU of 2mjq by Molmil
Structure of antimicrobial peptide anoplin in DPC micelles
Descriptor: Anoplin, UNKNOWN ATOM OR ION, dodecyl 2-(trimethylammonio)ethyl phosphate
Authors:Uggerhoej, L, Poulsen, T.J, Wimmer, R.
Deposit date:2014-01-16
Release date:2014-12-03
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Rational Design of Alpha-Helical Antimicrobial Peptides: Do's and Don'ts.
Chembiochem, 16, 2015
3PFK
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BU of 3pfk by Molmil
PHOSPHOFRUCTOKINASE. STRUCTURE AND CONTROL
Descriptor: PHOSPHATE ION, PHOSPHOFRUCTOKINASE
Authors:Evans, P.R, Hudson, P.J.
Deposit date:1988-01-25
Release date:1989-01-09
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Phosphofructokinase: structure and control.
Philos.Trans.R.Soc.London,Ser.B, 293, 1981
7KR4
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BU of 7kr4 by Molmil
Human DNA Ligase 1(E346A/E592A) Bound to a nicked DNA substrate control duplex
Descriptor: ACETATE ION, ADENOSINE MONOPHOSPHATE, DNA (5'-D(*AP*AP*TP*GP*TP*CP*TP*GP*CP*CP*C)-3'), ...
Authors:Tumbale, P.P, Williams, R.S.
Deposit date:2020-11-18
Release date:2021-02-03
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:High-fidelity DNA ligation enforces accurate Okazaki fragment maturation during DNA replication.
Nat Commun, 12, 2021
7L35
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BU of 7l35 by Molmil
Human DNA Ligase 1 - R771W nicked DNA complex
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE MONOPHOSPHATE, DI(HYDROXYETHYL)ETHER, ...
Authors:Tumbale, P.P, Williams, R.S, Schellenberg, M.S.
Deposit date:2020-12-17
Release date:2021-01-13
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:LIG1 syndrome mutations remodel a cooperative network of ligand binding interactions to compromise ligation efficiency.
Nucleic Acids Res., 49, 2021
2MCU
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BU of 2mcu by Molmil
Solid-state NMR structure of piscidin 1 in aligned 3:1 phosphatidylcholine/phosphoglycerol lipid bilayers
Descriptor: Moronecidin
Authors:Fu, R, Tian, Y, Perrin Jr, B.S, Grant, C.V, Pastor, R.W, Cotten, M.L.
Deposit date:2013-08-27
Release date:2014-01-22
Last modified:2014-03-19
Method:SOLID-STATE NMR
Cite:High-resolution structures and orientations of antimicrobial peptides piscidin 1 and piscidin 3 in fluid bilayers reveal tilting, kinking, and bilayer immersion.
J.Am.Chem.Soc., 136, 2014
2MJT
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BU of 2mjt by Molmil
Anoplin R5F T8W in DPC micelles
Descriptor: Anoplin, UNKNOWN ATOM OR ION, dodecyl 2-(trimethylammonio)ethyl phosphate
Authors:Uggerhoej, L, Poulsen, T.J, Wimmer, R.
Deposit date:2014-01-16
Release date:2014-12-03
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Rational Design of Alpha-Helical Antimicrobial Peptides: Do's and Don'ts.
Chembiochem, 16, 2015
4UQJ
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BU of 4uqj by Molmil
Cryo-EM density map of GluA2em in complex with ZK200775
Descriptor: GLUTAMATE RECEPTOR 2, {[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl]methyl}phosphonic acid
Authors:Meyerson, J.R, Kumar, J, Chittori, S, Rao, P, Pierson, J, Bartesaghi, A, Mayer, M.L, Subramaniam, S.
Deposit date:2014-06-24
Release date:2014-08-13
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (10.4 Å)
Cite:Structural Mechanism of Glutamate Receptor Activation and Desensitization
Nature, 514, 2014
4UQK
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BU of 4uqk by Molmil
Electron density map of GluA2em in complex with quisqualate and LY451646
Descriptor: (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, GLUTAMATE RECEPTOR 2
Authors:Meyerson, J.R, Kumar, J, Chittori, S, Rao, P, Pierson, J, Bartesaghi, A, Mayer, M.L, Subramaniam, S.
Deposit date:2014-06-24
Release date:2014-08-13
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (16.4 Å)
Cite:Structural Mechanism of Glutamate Receptor Activation and Desensitization
Nature, 514, 2014
6TVG
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BU of 6tvg by Molmil
Human CD73 (ecto 5'-nucleotidase) in complex with AMPCP in the open state
Descriptor: 5'-nucleotidase, ecto (CD73), isoform CRA_a, ...
Authors:Scaletti, E, Strater, N.
Deposit date:2020-01-09
Release date:2020-02-26
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:2-Substituted alpha , beta-Methylene-ADP Derivatives: Potent Competitive Ecto-5'-nucleotidase (CD73) Inhibitors with Variable Binding Modes.
J.Med.Chem., 63, 2020
1RCT
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BU of 1rct by Molmil
Crystal structure of Human purine nucleoside phosphorylase complexed with INOSINE
Descriptor: INOSINE, Purine nucleoside phosphorylase, SULFATE ION
Authors:Canduri, F, dos Santos, D.M, Silva, R.G, Mendes, M.A, Palma, M.S, de Azevedo Jr, W.F, Basso, L.A, Santos, D.S.
Deposit date:2003-11-04
Release date:2004-01-20
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structures of human purine nucleoside phosphorylase complexed with inosine and ddI
Biochem.Biophys.Res.Commun., 313, 2004
1S3G
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BU of 1s3g by Molmil
Crystal structure of adenylate kinase from Bacillus globisporus
Descriptor: Adenylate kinase, BIS(ADENOSINE)-5'-PENTAPHOSPHATE, ZINC ION
Authors:Bae, E, Phillips Jr, G.N.
Deposit date:2004-01-13
Release date:2004-05-04
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structures and analysis of highly homologous psychrophilic, mesophilic, and thermophilic adenylate kinases.
J.Biol.Chem., 279, 2004
6SLT
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BU of 6slt by Molmil
Flavin-dependent tryptophan 6-halogenase Thal in complex with tryptophan and FAD
Descriptor: ADENOSINE MONOPHOSPHATE, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ...
Authors:Moritzer, A, Niemann, H.H.
Deposit date:2019-08-20
Release date:2019-10-16
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Binding of FAD and tryptophan to the tryptophan 6-halogenase Thal is negatively coupled.
Protein Sci., 28, 2019
1V3Q
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BU of 1v3q by Molmil
Structure of human PNP complexed with DDI
Descriptor: 9-[(2R,5R)-5-(HYDROXYMETHYL)TETRAHYDROFURAN-2-YL]-1,9-DIHYDRO-6H-PURIN-6-ONE, Purine nucleoside phosphorylase, SULFATE ION
Authors:Canduri, F, Pereira, J.H, dos Santos, D.M, Silva, R.G, Palma, M.S, Basso, L.A, de Azevedo Jr, W.F, Santos, D.S.
Deposit date:2003-11-04
Release date:2004-01-20
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structures of human purine nucleoside phosphorylase complexed with inosine and ddI
Biochem.Biophys.Res.Commun., 313, 2004
6U7B
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BU of 6u7b by Molmil
Structure of E. coli MS115-1 CdnC:HORMA-deltaN complex
Descriptor: ACETATE ION, ADENOSINE MONOPHOSPHATE, CHLORIDE ION, ...
Authors:Ye, Q, Corbett, K.D.
Deposit date:2019-09-02
Release date:2019-12-25
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:HORMA Domain Proteins and a Trip13-like ATPase Regulate Bacterial cGAS-like Enzymes to Mediate Bacteriophage Immunity.
Mol.Cell, 77, 2020
7XN3
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BU of 7xn3 by Molmil
E.coli phosphoribosylpyrophosphate (PRPP) synthetase type B filament bound with Pi
Descriptor: PHOSPHATE ION, Ribose-phosphate pyrophosphokinase
Authors:Hu, H.H, Lu, G.M, Chang, C.C, Liu, J.L.
Deposit date:2022-04-27
Release date:2022-06-29
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Filamentation modulates allosteric regulation of PRPS.
Elife, 11, 2022
7XMU
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BU of 7xmu by Molmil
E.coli phosphoribosylpyrophosphate (PRPP) synthetase type A filament bound with ADP, Pi and R5P
Descriptor: 5-O-phosphono-alpha-D-ribofuranose, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Hu, H.H, Lu, G.M, Chang, C.C, Liu, J.L.
Deposit date:2022-04-26
Release date:2022-06-29
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (2.3 Å)
Cite:Filamentation modulates allosteric regulation of PRPS.
Elife, 11, 2022

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數據於2024-10-09公開中

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