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2R7F
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BU of 2r7f by Molmil
Crystal structure of ribonuclease II family protein from Deinococcus radiodurans, hexagonal crystal form. NorthEast Structural Genomics target DrR63
Descriptor: Ribonuclease II family protein
Authors:Seetharaman, J, Neely, H, Forouhar, F, Wang, D, Fang, Y, Cunningham, K, Ma, L.-C, Xia, R, Liu, J, Baran, M.C, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
Deposit date:2007-09-07
Release date:2007-10-02
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The Structure and Enzymatic Properties of a Novel RNase II Family Enzyme from Deinococcus radiodurans.
J.Mol.Biol., 415, 2012
5T9P
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BU of 5t9p by Molmil
Structural analysis reveals the flexible C-terminus of Nop15 undergoes rearrangement to recognize a pre-ribosomal RNA folding intermediate
Descriptor: CHLORIDE ION, Ribosome biogenesis protein 15, SULFATE ION
Authors:Zhang, J, Gonzalez, E.L, Hall, M.T.T.
Deposit date:2016-09-09
Release date:2016-11-16
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural analysis reveals the flexible C-terminus of Nop15 undergoes rearrangement to recognize a pre-ribosomal RNA folding intermediate.
Nucleic Acids Res., 45, 2017
6KLH
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BU of 6klh by Molmil
Dimeric structure of Machupo virus polymerase bound to vRNA promoter
Descriptor: MANGANESE (II) ION, RNA (5'-R(*GP*CP*CP*UP*AP*GP*GP*AP*UP*CP*CP*AP*CP*UP*GP*UP*GP*CP*G)-3'), RNA-directed RNA polymerase L, ...
Authors:Peng, R, Xu, X, Jing, J, Peng, Q, Gao, G.F, Shi, Y.
Deposit date:2019-07-30
Release date:2020-03-18
Last modified:2021-12-08
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural insight into arenavirus replication machinery.
Nature, 579, 2020
7ELH
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BU of 7elh by Molmil
In situ structure of transcriptional enzyme complex and capsid shell protein of mammalian reovirus at initiation state
Descriptor: Lambda 1, Minor core protein mu2, PHOSPHATE ION, ...
Authors:Zhou, Z.H, Pan, M.
Deposit date:2021-04-11
Release date:2021-10-20
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Asymmetric reconstruction of mammalian reovirus reveals interactions among RNA, transcriptional factor mu2 and capsid proteins.
Nat Commun, 12, 2021
2F96
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BU of 2f96 by Molmil
2.1 A crystal structure of Pseudomonas aeruginosa rnase T (Ribonuclease T)
Descriptor: MAGNESIUM ION, Ribonuclease T
Authors:Zheng, H, Chruszcz, M, Cymborowski, M, Wang, Y, Gorodichtchenskaia, E, Skarina, T, Guthrie, J, Savchenko, A, Edwards, A, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG)
Deposit date:2005-12-05
Release date:2006-02-14
Last modified:2022-04-13
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Crystal Structure of RNase T, an Exoribonuclease Involved in tRNA Maturation and End Turnover.
Structure, 15, 2007
2KG1
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BU of 2kg1 by Molmil
Structure of the third qRRM domain of hnRNP F in complex with a AGGGAU G-tract RNA
Descriptor: 5'-R(*AP*GP*GP*GP*AP*U)-3', Heterogeneous nuclear ribonucleoprotein F
Authors:Allain, F.H.T, Dominguez, C.
Deposit date:2009-03-02
Release date:2010-06-09
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structural basis of G-tract recognition and encaging by hnRNP F quasi-RRMs.
Nat.Struct.Mol.Biol., 17, 2010
2KG0
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BU of 2kg0 by Molmil
Structure of the second qRRM domain of hnRNP F in complex with a AGGGAU G-tract RNA
Descriptor: 5'-R(*AP*GP*GP*GP*AP*U)-3', Heterogeneous nuclear ribonucleoprotein F
Authors:Allain, F.H.T, Dominguez, C.
Deposit date:2009-03-02
Release date:2010-06-09
Last modified:2024-05-08
Method:SOLUTION NMR
Cite:Structural basis of G-tract recognition and encaging by hnRNP F quasi-RRMs.
Nat.Struct.Mol.Biol., 17, 2010
8C5C
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BU of 8c5c by Molmil
microtubule decorated with tubulin oligomers in presence of APC C-terminal domain. (here only map corresponding to the 13-pf microtubule is represented)
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Serre, L, Arnal, I.
Deposit date:2023-01-06
Release date:2023-01-25
Last modified:2023-02-01
Method:ELECTRON MICROSCOPY (5.3 Å)
Cite:The mitotic role of adenomatous polyposis coli requires its bilateral interaction with tubulin and microtubules.
J.Cell.Sci., 136, 2023
6W15
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BU of 6w15 by Molmil
Crystal structure of tRNA (guanine-N(1)-)-methyltransferase with bound SAH from Mycobacterium smegmatis
Descriptor: S-ADENOSYL-L-HOMOCYSTEINE, tRNA (guanine-N(1)-)-methyltransferase
Authors:Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2020-03-03
Release date:2020-05-06
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of tRNA (guanine-N(1)-)-methyltransferase with bound SAH from Mycobacterium smegmatis
to be published
7CSZ
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BU of 7csz by Molmil
Crystal structure of the N-terminal tandem RRM domains of RBM45 in complex with single-stranded DNA
Descriptor: DNA (5'-D(*CP*GP*AP*CP*GP*GP*GP*AP*CP*GP*C)-3'), RNA-binding protein 45
Authors:Chen, X, Yang, Z, Wang, W, Wang, M.
Deposit date:2020-08-17
Release date:2021-02-03
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for RNA recognition by the N-terminal tandem RRM domains of human RBM45.
Nucleic Acids Res., 49, 2021
2DIW
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BU of 2diw by Molmil
Solution structure of the RPR domain of Putative RNA-binding protein 16
Descriptor: Putative RNA-binding protein 16
Authors:Dang, W, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Terada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2006-03-30
Release date:2006-09-30
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of the RPR domain of Putative RNA-binding protein 16
To be Published
7V02
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BU of 7v02 by Molmil
Staphylococcus epidermidis RP62A CRISPR short effector complex
Descriptor: CRISPR system Cms endoribonuclease Csm3, CRISPR system Cms protein Csm2, CRISPR system Cms protein Csm4, ...
Authors:Smith, E.M, Ferrell, S.H, Tokars, V.L, Mondragon, A.
Deposit date:2022-05-09
Release date:2022-07-06
Last modified:2022-08-17
Method:ELECTRON MICROSCOPY (4.97 Å)
Cite:Structures of an active type III-A CRISPR effector complex.
Structure, 30, 2022
7UZZ
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BU of 7uzz by Molmil
Staphylococcus epidermidis RP62a CRISPR tall effector complex
Descriptor: CRISPR system Cms endoribonuclease Csm3, CRISPR system Cms protein Csm2, CRISPR system Cms protein Csm4, ...
Authors:Smith, E.M, Ferrell, S.H, Tokars, V.L, Mondragon, A.
Deposit date:2022-05-09
Release date:2022-07-06
Last modified:2022-08-17
Method:ELECTRON MICROSCOPY (4.45 Å)
Cite:Structures of an active type III-A CRISPR effector complex.
Structure, 30, 2022
7RDX
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BU of 7rdx by Molmil
SARS-CoV-2 replication-transcription complex bound to nsp13 helicase - nsp13(2)-RTC - open class
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, CHAPSO, ...
Authors:Chen, J, Malone, B, Campbell, E.A, Darst, S.A.
Deposit date:2021-07-12
Release date:2021-11-24
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Ensemble cryo-EM reveals conformational states of the nsp13 helicase in the SARS-CoV-2 helicase replication-transcription complex.
Nat.Struct.Mol.Biol., 29, 2022
7RDZ
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BU of 7rdz by Molmil
SARS-CoV-2 replication-transcription complex bound to nsp13 helicase - nsp13(2)-RTC - apo class
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Helicase, MAGNESIUM ION, ...
Authors:Chen, J, Malone, B, Campbell, E.A, Darst, S.A.
Deposit date:2021-07-12
Release date:2021-11-24
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Ensemble cryo-EM reveals conformational states of the nsp13 helicase in the SARS-CoV-2 helicase replication-transcription complex.
Nat.Struct.Mol.Biol., 29, 2022
7RE3
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BU of 7re3 by Molmil
SARS-CoV-2 replication-transcription complex bound to nsp13 helicase - nsp13(2)-RTC dimer
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, CHAPSO, ...
Authors:Chen, J, Malone, B, Campbell, E.A, Darst, S.A.
Deposit date:2021-07-12
Release date:2021-11-24
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.33 Å)
Cite:Ensemble cryo-EM reveals conformational states of the nsp13 helicase in the SARS-CoV-2 helicase replication-transcription complex.
Nat.Struct.Mol.Biol., 29, 2022
6O8W
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BU of 6o8w by Molmil
Cryo-EM image reconstruction of the 70S Ribosome Enterococcus faecalis Class01
Descriptor: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Jogl, G, Khayat, R.
Deposit date:2019-03-12
Release date:2020-09-23
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.53 Å)
Cite:Cryo-electron microscopy structure of the 70S ribosome from Enterococcus faecalis.
Sci Rep, 10, 2020
7RE1
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BU of 7re1 by Molmil
SARS-CoV-2 replication-transcription complex bound to nsp13 helicase - nsp13(2)-RTC (composite)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, CHAPSO, ...
Authors:Chen, J, Malone, B, Campbell, E.A, Darst, S.A.
Deposit date:2021-07-12
Release date:2021-12-01
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (2.91 Å)
Cite:Ensemble cryo-EM reveals conformational states of the nsp13 helicase in the SARS-CoV-2 helicase replication-transcription complex.
Nat.Struct.Mol.Biol., 29, 2022
7RE2
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BU of 7re2 by Molmil
SARS-CoV-2 replication-transcription complex bound to nsp13 helicase - nsp13(1)-RTC
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, CHAPSO, ...
Authors:Chen, J, Malone, B, Campbell, E.A, Darst, S.A.
Deposit date:2021-07-12
Release date:2021-12-01
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.17 Å)
Cite:Ensemble cryo-EM reveals conformational states of the nsp13 helicase in the SARS-CoV-2 helicase replication-transcription complex.
Nat.Struct.Mol.Biol., 29, 2022
7RDY
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BU of 7rdy by Molmil
SARS-CoV-2 replication-transcription complex bound to nsp13 helicase - nsp13(2)-RTC - engaged class
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, CHAPSO, ...
Authors:Chen, J, Malone, B, Campbell, E.A, Darst, S.A.
Deposit date:2021-07-12
Release date:2021-12-01
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Ensemble cryo-EM reveals conformational states of the nsp13 helicase in the SARS-CoV-2 helicase replication-transcription complex.
Nat.Struct.Mol.Biol., 29, 2022
7RE0
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BU of 7re0 by Molmil
SARS-CoV-2 replication-transcription complex bound to nsp13 helicase - nsp13(2)-RTC - swiveled class
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, Helicase, ...
Authors:Chen, J, Malone, B, Campbell, E.A, Darst, S.A.
Deposit date:2021-07-12
Release date:2021-12-01
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Ensemble cryo-EM reveals conformational states of the nsp13 helicase in the SARS-CoV-2 helicase replication-transcription complex.
Nat.Struct.Mol.Biol., 29, 2022
8PFJ
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BU of 8pfj by Molmil
fully recruited RfaH bound to E. coli transcription complex paused at ops site (not fully complementary scaffold; alternative state of RfaH)
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Zuber, P.K, Said, N, Hilal, T, Loll, B, Wahl, M.C, Knauer, S.H.
Deposit date:2023-06-16
Release date:2024-04-24
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Concerted transformation of a hyper-paused transcription complex and its reinforcing protein.
Nat Commun, 15, 2024
1XBP
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BU of 1xbp by Molmil
Inhibition of peptide bond formation by pleuromutilins: The structure of the 50S ribosomal subunit from Deinococcus radiodurans in complex with Tiamulin
Descriptor: 23S RIBOSOMAL RNA, 50S ribosomal protein L11, 50S ribosomal protein L13, ...
Authors:Schluenzen, F, Pyetan, E, Fucini, P, Yonath, A, Harms, J.M.
Deposit date:2004-08-31
Release date:2005-03-01
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Inhibition of peptide bond formation by pleuromutilins: the structure of the 50S ribosomal subunit from Deinococcus radiodurans in complex with tiamulin.
Mol.Microbiol., 54, 2004
7BMK
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BU of 7bmk by Molmil
ATP-Competitive Partial Antagonists-'PAIR's-Rheostatically Modulate IRE1alpha's Kinase Helix-alphaC to Segregate its RNase-Mediated Biological Outputs
Descriptor: 1,2-ETHANEDIOL, 2,2,2-tris(fluoranyl)-~{N}-[4-[3-[2-[[(3~{S})-piperidin-3-yl]amino]pyrimidin-4-yl]pyridin-2-yl]oxynaphthalen-1-yl]ethanesulfonamide, DI(HYDROXYETHYL)ETHER, ...
Authors:Feldman, H.C, Ghosh, R, Auyeung, V, Mueller, J.L, Vidadala, V.N, Olivier, A, Backes, B.J, Zikherman, J, Papa, F.R, Maly, D.J.
Deposit date:2021-01-20
Release date:2021-09-29
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:ATP-competitive partial antagonists of the IRE1 alpha RNase segregate outputs of the UPR.
Nat.Chem.Biol., 17, 2021
8PEN
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BU of 8pen by Molmil
fully recruited RfaH bound to E. coli transcription complex paused at ops site (alternative state of RfaH)
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Zuber, P.K, Said, N, Hilal, T, Loll, B, Wahl, M.C, Knauer, S.H.
Deposit date:2023-06-14
Release date:2024-04-24
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Concerted transformation of a hyper-paused transcription complex and its reinforcing protein.
Nat Commun, 15, 2024

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數據於2024-09-18公開中

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