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5D4E
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BU of 5d4e by Molmil
Crystal structure of Thermus thermophilus product complex for transcription initiation with 3'-dephosphate-CoA and CTP
Descriptor: CYTIDINE-5'-MONOPHOSPHATE, DEPHOSPHO COENZYME A, DIPHOSPHATE, ...
Authors:Zhang, Y, Ebright, R.H.
Deposit date:2015-08-07
Release date:2016-07-06
Last modified:2024-07-03
Method:X-RAY DIFFRACTION (3.08 Å)
Cite:The mechanism of RNA 5' capping with NAD(+), NADH and desphospho-CoA.
Nature, 535, 2016
6UD7
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BU of 6ud7 by Molmil
Crystal structure of full-length human DCAF15-DDB1(deltaBPB)-DDA1-RBM39 in complex with indisulam
Descriptor: DDB1- and CUL4-associated factor 15, DET1- and DDB1-associated protein 1, DNA damage-binding protein 1,DNA damage-binding protein 1, ...
Authors:Bussiere, D.E, Shu, W, Xie, L, Knapp, M.
Deposit date:2019-09-18
Release date:2019-12-18
Last modified:2020-01-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis of indisulam-mediated RBM39 recruitment to DCAF15 E3 ligase complex.
Nat.Chem.Biol., 16, 2020
8PFJ
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BU of 8pfj by Molmil
fully recruited RfaH bound to E. coli transcription complex paused at ops site (not fully complementary scaffold; alternative state of RfaH)
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Zuber, P.K, Said, N, Hilal, T, Loll, B, Wahl, M.C, Knauer, S.H.
Deposit date:2023-06-16
Release date:2024-04-24
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Concerted transformation of a hyper-paused transcription complex and its reinforcing protein.
Nat Commun, 15, 2024
8PEN
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BU of 8pen by Molmil
fully recruited RfaH bound to E. coli transcription complex paused at ops site (alternative state of RfaH)
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Zuber, P.K, Said, N, Hilal, T, Loll, B, Wahl, M.C, Knauer, S.H.
Deposit date:2023-06-14
Release date:2024-04-24
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Concerted transformation of a hyper-paused transcription complex and its reinforcing protein.
Nat Commun, 15, 2024
2BA1
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BU of 2ba1 by Molmil
Archaeal exosome core
Descriptor: Archaeal exosome RNA binding protein CSL4, Archaeal exosome complex exonuclease RRP41, Archaeal exosome complex exonuclease RRP42, ...
Authors:Hopfner, K.P, Buttner, K, Wenig, K.
Deposit date:2005-10-13
Release date:2005-11-22
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural framework for the mechanism of archaeal exosomes in RNA processing.
Mol.Cell, 20, 2005
2DR8
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BU of 2dr8 by Molmil
Complex structure of CCA-adding enzyme with tRNAminiDC and CTP
Descriptor: CCA-adding enzyme, CYTIDINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Tomita, K, Ishitani, R, Fukai, S, Nureki, O.
Deposit date:2006-06-08
Release date:2006-11-14
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Complete crystallographic analysis of the dynamics of CCA sequence addition
Nature, 443, 2006
2DRA
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BU of 2dra by Molmil
Complex structure of CCA-adding enzyme with tRNAminiDCC and ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CCA-adding enzyme, MAGNESIUM ION, ...
Authors:Tomita, K, Ishitani, R, Fukai, S, Nureki, O.
Deposit date:2006-06-08
Release date:2006-11-14
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Complete crystallographic analysis of the dynamics of CCA sequence addition
Nature, 443, 2006
4Y3C
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BU of 4y3c by Molmil
I304V 3D polymerase mutant of EMCV
Descriptor: 3D polymerase, CHLORIDE ION, GLYCEROL
Authors:Verdaguer, N, Ferrer-Orta, C, Vives-Adrian, L.
Deposit date:2015-02-10
Release date:2015-04-01
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:The RNA Template Channel of the RNA-Dependent RNA Polymerase as a Target for Development of Antiviral Therapy of Multiple Genera within a Virus Family.
Plos Pathog., 11, 2015
4Y2C
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BU of 4y2c by Molmil
M300V 3D polymerase mutant of EMCV
Descriptor: GLYCEROL, Genome polyprotein
Authors:Verdaguer, N, Ferrer-Orta, C, Vives-Adrian, L.
Deposit date:2015-02-09
Release date:2015-04-01
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The RNA Template Channel of the RNA-Dependent RNA Polymerase as a Target for Development of Antiviral Therapy of Multiple Genera within a Virus Family.
Plos Pathog., 11, 2015
7TO1
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BU of 7to1 by Molmil
Cryo-EM structure of RIG-I bound to the end of p3SLR30 (+ATP)
Descriptor: Antiviral innate immune response receptor RIG-I, ZINC ION, p3SLR30
Authors:Wang, W, Pyle, A.M.
Deposit date:2022-01-22
Release date:2022-11-02
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.66 Å)
Cite:The RIG-I receptor adopts two different conformations for distinguishing host from viral RNA ligands.
Mol.Cell, 82, 2022
4DF3
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BU of 4df3 by Molmil
Crystal Structure of Aeropyrum pernix fibrillarin in complex with natively bound S-adenosyl-L-methionine at 1.7A
Descriptor: Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase, S-ADENOSYLMETHIONINE
Authors:de Silva, U.
Deposit date:2012-01-22
Release date:2012-08-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Structure of Aeropyrum pernix fibrillarin in complex with natively bound S-adenosyl-L-methionine at 1.7 A resolution.
Acta Crystallogr.,Sect.F, 68, 2012
8E5P
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BU of 8e5p by Molmil
Escherichia coli Rho-dependent transcription pre-termination complex containing 24 nt long RNA spacer, Mg-ADP-BeF3, and NusG; Rho hexamer part
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ...
Authors:Molodtsov, V, Wang, C.
Deposit date:2022-08-22
Release date:2022-09-07
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Structural basis of Rho-dependent transcription termination.
Nature, 614, 2023
8E6W
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BU of 8e6w by Molmil
Escherichia coli Rho-dependent transcription pre-termination complex containing 18 nt long RNA spacer, lambda-tR1 rut RNA, Mg-ADP-BeF3, and NusG; Rho part
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ...
Authors:Molodtsov, V, Wang, C, Ebright, R.H.
Deposit date:2022-08-23
Release date:2022-09-07
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (4.27 Å)
Cite:Structural basis of Rho-dependent transcription termination.
Nature, 614, 2023
8E70
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BU of 8e70 by Molmil
Escherichia coli Rho-dependent transcription pre-termination complex containing 18 nt long RNA spacer, dC75 rut mimic RNA, Mg-ADP-BeF3, and NusG; Rho hexamer part
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ...
Authors:Molodtsov, V, Wang, C, Ebright, R.H.
Deposit date:2022-08-23
Release date:2022-09-07
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structural basis of Rho-dependent transcription termination.
Nature, 614, 2023
4RVQ
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BU of 4rvq by Molmil
PWI-like domain of Chaetomium thermophilum Brr2
Descriptor: 1,2-ETHANEDIOL, Pre-mRNA splicing helicase-like protein, SULFATE ION
Authors:Absmeier, E, Rosenberger, L, Santos, K.F, Becke, C, Wahl, M.C.
Deposit date:2014-11-27
Release date:2015-04-01
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.135 Å)
Cite:A noncanonical PWI domain in the N-terminal helicase-associated region of the spliceosomal Brr2 protein.
Acta Crystallogr.,Sect.D, 71, 2015
8PH9
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BU of 8ph9 by Molmil
E. coli RNA polymerase paused at ops site (non-complementary scaffold)
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Zuber, P.K, Said, N, Hilal, T, Loll, B, Wahl, M.C, Knauer, S.H.
Deposit date:2023-06-19
Release date:2024-04-24
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Concerted transformation of a hyper-paused transcription complex and its reinforcing protein.
Nat Commun, 15, 2024
3J0L
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BU of 3j0l by Molmil
Core of mammalian 80S pre-ribosome in complex with tRNAs fitted to a 9.8A cryo-EM map: classic PRE state 1
Descriptor: 40S ribosomal RNA fragment, 60S ribosomal RNA fragment, Ribosomal protein L10, ...
Authors:Budkevich, T, Giesebrecht, J, Altman, R, Munro, J, Mielke, T, Nierhaus, K, Blanchard, S, Spahn, C.M.
Deposit date:2011-10-04
Release date:2011-11-16
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (9.8 Å)
Cite:Structure and dynamics of the Mammalian ribosomal pretranslocation complex.
Mol.Cell, 44, 2011
4Y2A
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BU of 4y2a by Molmil
Crystal Structure of Coxsackie Virus B3 3D polymerase in complex with GPC-N114 inhibitor
Descriptor: 2,2'-[(4-chlorobenzene-1,2-diyl)bis(oxy)]bis(5-nitrobenzonitrile), 3D polymerase, GLYCEROL, ...
Authors:Vives-Adrian, L, Ferrer-Orta, C, Verdaguer, N.
Deposit date:2015-02-09
Release date:2015-04-01
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The RNA Template Channel of the RNA-Dependent RNA Polymerase as a Target for Development of Antiviral Therapy of Multiple Genera within a Virus Family.
Plos Pathog., 11, 2015
2EY4
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BU of 2ey4 by Molmil
Crystal Structure of a Cbf5-Nop10-Gar1 Complex
Descriptor: Probable tRNA pseudouridine synthase B, Ribosome biogenesis protein Nop10, ZINC ION, ...
Authors:Rashid, R, Liang, B, Li, H, Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2005-11-09
Release date:2006-01-24
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:Crystal structure of a Cbf5-Nop10-Gar1 complex and implications in RNA-guided pseudouridylation and dyskeratosis congenita.
Mol.Cell, 21, 2006
2DR7
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BU of 2dr7 by Molmil
Complex structure of CCA-adding enzyme with tRNAminiDC
Descriptor: CCA-adding enzyme, SULFATE ION, tRNA (33-MER)
Authors:Tomita, K, Ishitani, R, Fukai, S, Nureki, O.
Deposit date:2006-06-08
Release date:2006-11-14
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Complete crystallographic analysis of the dynamics of CCA sequence addition
Nature, 443, 2006
2DRB
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BU of 2drb by Molmil
Complex structure of CCA-adding enzyme with tRNAminiCCA
Descriptor: CCA-adding enzyme, SULFATE ION, tRNA (35-MER)
Authors:Tomita, K, Ishitani, R, Fukai, S, Nureki, O.
Deposit date:2006-06-08
Release date:2006-11-14
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Complete crystallographic analysis of the dynamics of CCA sequence addition
Nature, 443, 2006
2DR9
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BU of 2dr9 by Molmil
Complex structure of CCA-adding enzyme with tRNAminiDCC
Descriptor: CCA-adding enzyme, SULFATE ION, tRNA (34-MER)
Authors:Tomita, K, Ishitani, R, Fukai, S, Nureki, O.
Deposit date:2006-06-08
Release date:2006-11-14
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Complete crystallographic analysis of the dynamics of CCA sequence addition
Nature, 443, 2006
4XLQ
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BU of 4xlq by Molmil
Crystal structure of T.aquaticus transcription initiation complex containing upstream fork (-11 base-paired) promoter
Descriptor: DNA (26-MER), DNA (30-MER), DNA-directed RNA polymerase subunit alpha, ...
Authors:Bae, B, Darst, S.A.
Deposit date:2015-01-13
Release date:2015-09-23
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (4.6 Å)
Cite:Structure of a bacterial RNA polymerase holoenzyme open promoter complex.
Elife, 4, 2015
5Y7M
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BU of 5y7m by Molmil
Crystal structure of PhoRpp38 bound to a K-turn in P12.1 helix
Descriptor: 50S ribosomal protein L7Ae, GUANOSINE-5'-TRIPHOSPHATE, RNA (52-MER), ...
Authors:Oshima, K, Kimura, M.
Deposit date:2017-08-01
Release date:2018-02-07
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal structures of the archaeal RNase P protein Rpp38 in complex with RNA fragments containing a K-turn motif.
Acta Crystallogr F Struct Biol Commun, 74, 2018
4XLP
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BU of 4xlp by Molmil
Crystal structure of T.aquaticus transcription initiation complex containing upstream fork promoter
Descriptor: DNA (25-MER), DNA (30-MER), DNA-directed RNA polymerase subunit alpha, ...
Authors:Bae, B, Darst, S.A.
Deposit date:2015-01-13
Release date:2015-09-23
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (4 Å)
Cite:Structure of a bacterial RNA polymerase holoenzyme open promoter complex.
Elife, 4, 2015

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數據於2024-07-17公開中

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