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2QR0
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BU of 2qr0 by Molmil
Structure of VEGF complexed to a Fab containing TYR and SER in the CDRs
Descriptor: Fab-Fragment Heavy Chain, Fab-Fragment Light Chain, Vascular endothelial growth factor A
Authors:Wiesmann, C.
Deposit date:2007-07-27
Release date:2007-08-14
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:High-throughput generation of synthetic antibodies from highly functional minimalist phage-displayed libraries
J.Mol.Biol., 373, 2007
4HVW
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BU of 4hvw by Molmil
Crystal structure of the T98E c-Src-SH3 domain mutant in complex with the high affinity peptide VSL12
Descriptor: ACETYL GROUP, Proto-oncogene tyrosine-protein kinase Src, SULFATE ION, ...
Authors:Camara-Artigas, A.
Deposit date:2012-11-07
Release date:2013-05-01
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (0.98 Å)
Cite:Atomic resolution structures of the c-Src SH3 domain in complex with two high-affinity peptides from classes I and II.
Acta Crystallogr.,Sect.D, 69, 2013
3U8C
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BU of 3u8c by Molmil
Crystal structure of monomeric reversibly photoswitchable red fluorescent protein rsTagRFP in the ON state
Descriptor: Fluorescent protein rsTagRFP, GLYCEROL
Authors:Pletnev, S.
Deposit date:2011-10-16
Release date:2012-02-22
Last modified:2012-05-09
Method:X-RAY DIFFRACTION (2.188 Å)
Cite:A structural basis for reversible photoswitching of absorbance spectra in red fluorescent protein rsTagRFP.
J.Mol.Biol., 417, 2012
3U8X
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BU of 3u8x by Molmil
Crystal Structure of a chimera containing the N-terminal domain (residues 8-29) of drosophila Ciboulot and the C-terminal domain (residues 18-44) of bovine Thymosin-beta4, bound to G-actin-ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Renault, L, Husson, C, Carlier, M.F, Didry, D.
Deposit date:2011-10-17
Release date:2012-01-25
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:How a single residue in individual beta-thymosin/WH2 domains controls their functions in actin assembly
Embo J., 31, 2012
3H7S
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BU of 3h7s by Molmil
Crystal structures of K63-linked di- and tri-ubiquitin reveal a highly extended chain architecture
Descriptor: Ubiquitin, ZINC ION
Authors:Weeks, S.D, Grasty, K.C, Hernandez-Cuebas, L, Loll, P.J.
Deposit date:2009-04-28
Release date:2009-09-22
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures of Lys-63-linked tri- and di-ubiquitin reveal a highly extended chain architecture.
Proteins, 77, 2009
4HTT
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BU of 4htt by Molmil
Crystal Structure of Twin Arginine Translocase Receptor- TatC in DDM
Descriptor: Sec-independent protein translocase protein TatC, Lysozyme
Authors:Ramasamy, S, Suloway, C.J.M, Clemons Jr, W.M.
Deposit date:2012-11-01
Release date:2013-05-01
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (6.8 Å)
Cite:The Glove-like Structure of the Conserved Membrane Protein TatC Provides Insight into Signal Sequence Recognition in Twin-Arginine Translocation.
Structure, 21, 2013
2QV3
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BU of 2qv3 by Molmil
Crystal Structure of the Helicobacter pylori Vacuolating Toxin p55 Domain
Descriptor: Vacuolating cytotoxin
Authors:Gangwer, K.A.
Deposit date:2007-08-07
Release date:2007-10-23
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.401 Å)
Cite:Crystal structure of the Helicobacter pylori vacuolating toxin p55 domain
Proc.Natl.Acad.Sci.Usa, 104, 2007
4HWJ
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BU of 4hwj by Molmil
Crystal Structure of the Human C3a desArg anaphylatoxin
Descriptor: Complement C3, SULFATE ION
Authors:Bajic, G, Yatime, L, Andersen, G.R.
Deposit date:2012-11-08
Release date:2012-12-12
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Human C3a and C3a desArg anaphylatoxins have conserved structures, in contrast to C5a and C5a desArg.
Protein Sci., 22, 2013
3UAM
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BU of 3uam by Molmil
Crystal structure of a chitin binding domain from Burkholderia pseudomallei
Descriptor: Chitin binding domain, GLYCEROL, NITRATE ION
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2011-10-21
Release date:2011-11-02
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of a chitin binding domain from Burkholderia pseudomallei
to be published
3UBN
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BU of 3ubn by Molmil
Influenza hemagglutinin from the 2009 pandemic in complex with ligand 6SLN
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, ...
Authors:Xu, R, Wilson, I.A.
Deposit date:2011-10-24
Release date:2011-11-23
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.5079 Å)
Cite:Structural Characterization of the Hemagglutinin Receptor Specificity from the 2009 H1N1 Influenza Pandemic.
J.Virol., 86, 2012
4I1U
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BU of 4i1u by Molmil
Apo crystal structure of a dephospho-CoA kinase from Burkholderia vietnamiensis
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Dephospho-CoA kinase, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2012-11-21
Release date:2013-01-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Apo crystal structure of a dephospho-CoA kinase from Burkholderia vietnamiensis
TO BE PUBLISHED
4HXS
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BU of 4hxs by Molmil
Brd4 Bromodomain 1 complex with N-[3-(2-OXO-2,3-DIHYDRO-1,3-THIAZOL-4-YL)PHENYL]-1-PHENYLMETHANESULFONAMIDE inhibitor
Descriptor: Bromodomain-containing protein 4, N-[3-(2-oxo-2,3-dihydro-1,3-thiazol-4-yl)phenyl]-1-phenylmethanesulfonamide
Authors:Chen, T.T, Cao, D.Y, Chen, W.Y, Xiong, B, Shen, J.K, Xu, Y.C.
Deposit date:2012-11-12
Release date:2013-04-03
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.43 Å)
Cite:Fragment-Based Drug Discovery of 2-Thiazolidinones as Inhibitors of the Histone Reader BRD4 Bromodomain.
J.Med.Chem., 56, 2013
3H9Y
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BU of 3h9y by Molmil
Crystal structure of the IgE-Fc3-4 domains
Descriptor: AMMONIUM ION, Ig epsilon chain C region, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Wurzburg, B.A.
Deposit date:2009-04-30
Release date:2009-09-08
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Conformational flexibility in immunoglobulin E-Fc 3-4 revealed in multiple crystal forms.
J.Mol.Biol., 393, 2009
3TJE
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BU of 3tje by Molmil
Crystal structure of Fas receptor extracellular domain in complex with Fab E09
Descriptor: 1,2-ETHANEDIOL, CADMIUM ION, CHLORIDE ION, ...
Authors:Zuger, S, Stirnimann, C, Briand, C, Grutter, M.G.
Deposit date:2011-08-24
Release date:2012-05-09
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:A series of Fas receptor agonist antibodies that demonstrate an inverse correlation between affinity and potency.
Cell Death Differ., 19, 2012
4HYO
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BU of 4hyo by Molmil
Crystal Structure of MthK Pore
Descriptor: Calcium-gated potassium channel mthK, HEXANE-1,6-DIOL, POTASSIUM ION
Authors:Posson, D.J, McCoy, J.G, Nimigean, C.M.
Deposit date:2012-11-13
Release date:2012-12-26
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:The voltage-dependent gate in MthK potassium channels is located at the selectivity filter.
Nat.Struct.Mol.Biol., 20, 2013
2QXL
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BU of 2qxl by Molmil
Crystal Structure Analysis of Sse1, a yeast Hsp110
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein homolog SSE1, MAGNESIUM ION, ...
Authors:Hendrickson, W.A, Liu, Q.
Deposit date:2007-08-12
Release date:2007-10-23
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Insights into hsp70 chaperone activity from a crystal structure of the yeast hsp110 Sse1.
Cell(Cambridge,Mass.), 131, 2007
2R45
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BU of 2r45 by Molmil
Crystal structure of Escherichia coli Glycerol-3-phosphate Dehydrogenase in complex with 2-phospho-d-glyceric acid
Descriptor: 1,2-ETHANEDIOL, 2-PHOSPHOGLYCERIC ACID, Aerobic glycerol-3-phosphate dehydrogenase, ...
Authors:Yeh, J.I, Du, S, Chinte, U.
Deposit date:2007-08-30
Release date:2008-04-15
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of glycerol-3-phosphate dehydrogenase, an essential monotopic membrane enzyme involved in respiration and metabolism
Proc.Natl.Acad.Sci.USA, 105, 2008
4HZK
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BU of 4hzk by Molmil
Crystal structure of free CRM1 (crystal form 2)
Descriptor: CRM1 Nuclear transport receptor
Authors:Monecke, T, Neumann, P, Dickmanns, A, Ficner, R.
Deposit date:2012-11-15
Release date:2013-01-23
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural basis for cooperativity of CRM1 export complex formation.
Proc.Natl.Acad.Sci.USA, 110, 2013
2QAP
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BU of 2qap by Molmil
Fructose-1,6-bisphosphate aldolase from Leishmania mexicana
Descriptor: Fructose-1,6-bisphosphate aldolase, PHOSPHATE ION
Authors:Lafrance-Vanasse, J, Sygusch, J.
Deposit date:2007-06-15
Release date:2007-08-21
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Carboxy-Terminus Recruitment Induced by Substrate Binding in Eukaryotic Fructose Bis-phosphate Aldolases
Biochemistry, 46, 2007
3HC5
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BU of 3hc5 by Molmil
FXR with SRC1 and GSK826
Descriptor: 3-(6-{[3-(2,6-dichlorophenyl)-5-(1-methylethyl)isoxazol-4-yl]methoxy}-1-benzothiophen-2-yl)benzoic acid, Bile acid receptor, Nuclear receptor coactivator 1, ...
Authors:Williams, S.P, Madauss, K.P.
Deposit date:2009-05-05
Release date:2009-07-21
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:FXR agonist activity of conformationally constrained analogs of GW 4064.
Bioorg.Med.Chem.Lett., 19, 2009
2R18
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BU of 2r18 by Molmil
Structural insights into the multifunctional protein VP3 of Birnaviruses
Descriptor: Capsid assembly protein VP3
Authors:Casanas, A, Navarro, A, Ferrer-Orta, C, Gonzalez, D, Rodriguez, J.F, Verdaguer, N.
Deposit date:2007-08-22
Release date:2008-02-05
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural insights into the multifunctional protein VP3 of birnaviruses.
Structure, 16, 2008
3TM1
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BU of 3tm1 by Molmil
Crystal structure of mature ThnT, a pantetheine hydrolase
Descriptor: GLYCEROL, cysteine transferase
Authors:Schildbach, J.F, Wright, N.T, Buller, A.R.
Deposit date:2011-08-30
Release date:2012-07-04
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Autoproteolytic Activation of ThnT Results in Structural Reorganization Necessary for Substrate Binding and Catalysis.
J.Mol.Biol., 422, 2012
2QCP
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BU of 2qcp by Molmil
1.0 A Structure of CusF-Ag(I) residues 10-88 from Escherichia coli
Descriptor: Cation efflux system protein cusF, NITRATE ION, SILVER ION, ...
Authors:Loftin, I.R.
Deposit date:2007-06-19
Release date:2007-10-02
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1 Å)
Cite:Unusual Cu(I)/Ag(I) coordination of Escherichia coli CusF as revealed by atomic resolution crystallography and X-ray absorption spectroscopy
Protein Sci., 16, 2007
3GX0
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BU of 3gx0 by Molmil
Crystal Structure of GSH-dependent Disulfide bond Oxidoreductase
Descriptor: GST-like protein yfcG, OXIDIZED GLUTATHIONE DISULFIDE
Authors:Ladner, J.E, Harp, J.M, Wadington, M.C, Armstrong, R.N.
Deposit date:2009-04-01
Release date:2009-07-07
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Analysis of the structure and function of YfcG from Escherichia coli reveals an efficient and unique disulfide bond reductase.
Biochemistry, 48, 2009
3TN6
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BU of 3tn6 by Molmil
Crystal structure of GkaP mutant R230H from Geobacillus kaustophilus HTA426
Descriptor: COBALT (II) ION, Phosphotriesterase
Authors:An, J, Zhang, Z, Zhang, Y, Feng, Y, Wu, G.
Deposit date:2011-09-01
Release date:2012-09-12
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Engineering a thermostable lactonase for enhanced phosphotriesterase activity against organophosphate pesticides
to be published

223790

數據於2024-08-14公開中

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