3TM1

Crystal structure of mature ThnT, a pantetheine hydrolase

Summary for 3TM1

Entry DOI	10.2210/pdb3tm1/pdb
Related	3S3U
Descriptor	cysteine transferase, GLYCEROL (3 entities in total)
Functional Keywords	dom-fold, amidohydrolase, autoproteolytic, carbapenem, dmpa/oat superfamily, pantetheine hydrolase, thienamcyin biosynthesis, hydrolase
Biological source	Streptomyces cattleya
Total number of polymer chains	2
Total formula weight	82928.34
Authors	Schildbach, J.F.,Wright, N.T.,Buller, A.R. (deposition date: 2011-08-30, release date: 2012-07-04, Last modification date: 2024-02-28)
Primary citation	Buller, A.R.,Labonte, J.W.,Freeman, M.F.,Wright, N.T.,Schildbach, J.F.,Townsend, C.A. Autoproteolytic Activation of ThnT Results in Structural Reorganization Necessary for Substrate Binding and Catalysis. J.Mol.Biol., 422:508-518, 2012 Cited by PubMed: 22706025 DOI: 10.1016/j.jmb.2012.06.012 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation