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1W34
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BU of 1w34 by Molmil
FERREDOXIN-NADP REDUCTASE (MUTATION: Y 303 S)
Descriptor: FERREDOXIN-NADP REDUCTASE, FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION
Authors:Hermoso, J.A, Perez-Dorado, I, Medina, M, Julvez, M.M, Sanz-Aparicio, J, Gomez-Moreno, C.
Deposit date:2004-07-13
Release date:2005-10-19
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:C-Terminal Tyrosine of Ferredoxin-Nadp(+) Reductase in Hydride Transfer Processes with Nad(P)(+)/H.
Biochemistry, 44, 2005
1SN6
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BU of 1sn6 by Molmil
NMR solution structure of human Saposin C in SDS micelles
Descriptor: Proactivator polypeptide
Authors:Hawkins, C.A, de Alba, E, Tjandra, N.
Deposit date:2004-03-10
Release date:2005-03-01
Last modified:2024-11-13
Method:SOLUTION NMR
Cite:Solution structure of human saposin C in a detergent environment.
J.Mol.Biol., 346, 2005
3BUM
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BU of 3bum by Molmil
Crystal structure of c-Cbl-TKB domain complexed with its binding motif in Sprouty2
Descriptor: E3 ubiquitin-protein ligase CBL, Protein sprouty homolog 2
Authors:Ng, C, Jackson, A.R, Buschdorf, P.J, Sun, Q, Guy, R.G, Sivaraman, J.
Deposit date:2008-01-03
Release date:2008-02-26
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for a novel intrapeptidyl H-bond and reverse binding of c-Cbl-TKB domain substrates
Embo J., 27, 2008
4BSM
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BU of 4bsm by Molmil
Crystal structure of the Nuclear Export Receptor CRM1 (exportin-1) lacking the C-terminal helical extension at 4.5A
Descriptor: EXPORTIN-1
Authors:Dian, C, Bernaudat, F, Langer, K, Oliva, M.F, Fornerod, M, Schoehn, G, Muller, C.W, Petosa, C.
Deposit date:2013-06-10
Release date:2013-07-31
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (4.5 Å)
Cite:Structure of a Truncation Mutant of the Nuclear Export Factor Crm1 Provides Insights Into the Auto-Inhibitory Role of its C-Terminal Helix.
Structure, 21, 2013
4BSN
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BU of 4bsn by Molmil
Crystal structure of the Nuclear Export Receptor CRM1 (exportin-1) lacking the C-terminal helical extension at 4.1A
Descriptor: EXPORTIN-1
Authors:Dian, C, Bernaudat, F, Langer, K, Oliva, M.F, Fornerod, M, Schoehn, G, Muller, C.W, Petosa, C.
Deposit date:2013-06-11
Release date:2013-07-31
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (4.1 Å)
Cite:Structure of a Truncation Mutant of the Nuclear Export Factor Crm1 Provides Insights Into the Auto-Inhibitory Role of its C-Terminal Helix.
Structure, 21, 2013
3VKE
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BU of 3vke by Molmil
Contribution of the first K-homology domain of poly(C)-binding protein 1 to its affinity and specificity for C-rich oligonucleotides
Descriptor: DNA (5'-D(P*AP*CP*CP*CP*CP*A)-3'), Poly(rC)-binding protein 1
Authors:Traore, D.A.K, Wilce, M.C.J, Wilce, J.A.
Deposit date:2011-11-15
Release date:2012-02-29
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Contribution of the first K-homology domain of poly(C)-binding protein 1 to its affinity and specificity for C-rich oligonucleotides
Nucleic Acids Res., 40, 2012
2G15
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BU of 2g15 by Molmil
Structural Characterization of autoinhibited c-Met kinase
Descriptor: activated met oncogene
Authors:Wang, W, Marimuthu, A, Tsai, J, Kumar, A, Krupka, H.I, Zhang, C, Powell, B, Suzuki, Y, Nguyen, H, Tabrizizad, M, Luu, C, West, B.L.
Deposit date:2006-02-13
Release date:2006-03-21
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural characterization of autoinhibited c-Met kinase produced by coexpression in bacteria with phosphatase.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2G01
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BU of 2g01 by Molmil
Pyrazoloquinolones as Novel, Selective JNK1 inhibitors
Descriptor: 6-CHLORO-9-HYDROXY-1,3-DIMETHYL-1,9-DIHYDRO-4H-PYRAZOLO[3,4-B]QUINOLIN-4-ONE, C-jun-amino-terminal kinase-interacting protein 1, Mitogen-activated protein kinase 8, ...
Authors:Abad-Zapatero, C.
Deposit date:2006-02-10
Release date:2006-04-18
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Synthesis and SAR of 1,9-dihydro-9-hydroxypyrazolo[3,4-b]quinolin-4-ones as novel, selective c-Jun N-terminal kinase inhibitors.
Bioorg.Med.Chem.Lett., 16, 2006
1UX6
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BU of 1ux6 by Molmil
Structure of a thrombospondin C-terminal fragment reveals a novel calcium core in the type 3 repeats
Descriptor: CALCIUM ION, THROMBOSPONDIN-1
Authors:Kvansakul, M, Adams, J.C, Hohenester, E.
Deposit date:2004-02-19
Release date:2004-03-18
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of a Thrombospondin C-Terminal Fragment Reveals a Novel Calcium Core in the Type 3 Repeats
Embo J., 23, 2004
3CCN
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BU of 3ccn by Molmil
X-ray structure of c-Met with triazolopyridazine inhibitor.
Descriptor: 4-[(6-phenyl[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methyl]phenol, Hepatocyte growth factor receptor
Authors:Abrecht, B.K, Harmange, J.-C, Bauer, D, Dussault, I, long, A, Bellon, S.F.
Deposit date:2008-02-26
Release date:2008-04-29
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Discovery and Optimization of Triazolopyridazines as Potent and Selective Inhibitors of the c-Met Kinase.
J.Med.Chem., 51, 2008
3RHK
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BU of 3rhk by Molmil
Crystal structure of the catalytic domain of c-Met kinase in complex with ARQ 197
Descriptor: 1-[(3R,4R)-4-(1H-indol-3-yl)-2,5-dioxopyrrolidin-3-yl]pyrrolo[3,2,1-ij]quinolinium, Hepatocyte growth factor receptor
Authors:Eathiraj, S, Palma, R, Volckova, E, Hirschi, M, France, D.S, Ashwell, M.A, Chan, T.C.
Deposit date:2011-04-11
Release date:2011-04-27
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Discovery of a novel mode of protein kinase inhibition characterized by the mechanism of inhibition of human mesenchymal-epithelial transition factor (c-Met) protein autophosphorylation by ARQ 197.
J.Biol.Chem., 286, 2011
3CD8
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BU of 3cd8 by Molmil
X-ray Structure of c-Met with triazolopyridazine Inhibitor.
Descriptor: 7-methoxy-4-[(6-phenyl[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methoxy]quinoline, Hepatocyte growth factor receptor
Authors:Bellon, S.F, Albrecht, B.K, Harmange, J.-C, Bauer, D, Choquette, D, Dussault, I.
Deposit date:2008-02-26
Release date:2008-04-29
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Discovery and Optimization of Triazolopyridazines as Potent and Selective Inhibitors of the c-Met Kinase.
J.Med.Chem., 51, 2008
1TDB
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BU of 1tdb by Molmil
STRUCTURES OF THYMIDYLATE SYNTHASE WITH A C-TERMINAL DELETION: ROLE OF THE C-TERMINUS IN ALIGNMENT OF D/UMP AND CH2H4FOLATE
Descriptor: 5-FLUORO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE, THYMIDYLATE SYNTHASE
Authors:Perry, K.M, Carreras, C.W, Chang, L.C, Santi, D.V, Stroud, R.M.
Deposit date:1993-02-15
Release date:1993-07-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structures of thymidylate synthase with a C-terminal deletion: role of the C-terminus in alignment of 2'-deoxyuridine 5'-monophosphate and 5,10-methylenetetrahydrofolate.
Biochemistry, 32, 1993
1T0C
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BU of 1t0c by Molmil
Solution Structure of Human Proinsulin C-Peptide
Descriptor: Insulin
Authors:Munte, C.E, Vilela, L, Kalbitzer, H.-R, Garratt, R.C.
Deposit date:2004-04-08
Release date:2005-08-16
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure of human proinsulin C-peptide
Febs J., 272, 2005
1KNJ
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BU of 1knj by Molmil
Co-Crystal Structure of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate Synthase (ispF) from E. coli Involved in Mevalonate-Independent Isoprenoid Biosynthesis, Complexed with CMP/MECDP/Mn2+
Descriptor: 2C-METHYL-D-ERYTHRITOL 2,4-CYCLODIPHOSPHATE, 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, CYTIDINE-5'-MONOPHOSPHATE, ...
Authors:Richard, S.B, Ferrer, J.L, Bowman, M.E, Lillo, A.M, Tetzlaff, C.N, Cane, D.E, Noel, J.P.
Deposit date:2001-12-18
Release date:2002-06-18
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure and mechanism of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase. An enzyme in the mevalonate-independent isoprenoid biosynthetic pathway.
J.Biol.Chem., 277, 2002
1TDA
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BU of 1tda by Molmil
STRUCTURES OF THYMIDYLATE SYNTHASE WITH A C-TERMINAL DELETION: ROLE OF THE C-TERMINUS IN ALIGNMENT OF D/UMP AND CH2H4FOLATE
Descriptor: PHOSPHATE ION, THYMIDYLATE SYNTHASE
Authors:Perry, K.M, Carreras, C.W, Chang, L.C, Santi, D.V, Stroud, R.M.
Deposit date:1993-02-15
Release date:1993-07-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3.09 Å)
Cite:Structures of thymidylate synthase with a C-terminal deletion: role of the C-terminus in alignment of 2'-deoxyuridine 5'-monophosphate and 5,10-methylenetetrahydrofolate.
Biochemistry, 32, 1993
3ZJZ
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BU of 3zjz by Molmil
Open-form NavMS Sodium Channel Pore (with C-terminal Domain)
Descriptor: DODECAETHYLENE GLYCOL, HEGA-10, ION TRANSPORT PROTEIN, ...
Authors:Bagneris, C, Naylor, C.E, Wallace, B.A.
Deposit date:2013-01-21
Release date:2013-10-02
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.92 Å)
Cite:Role of the C-Terminal Domain in the Structure and Function of Tetrameric Sodium Channels.
Nat.Commun., 4, 2013
1MUZ
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BU of 1muz by Molmil
NMR STRUCTURE OF THE TUMOR SUPPRESSOR BIN1: ALTERNATIVE SPLICING IN MELANOMA AND INTERACTION WITH C-MYC
Descriptor: Myc box dependent interacting protein 1
Authors:Pineda-Lucena, A, Arrowsmith, C.H.
Deposit date:2002-09-24
Release date:2003-09-30
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:A structure-based model of the c-Myc/Bin1 protein interaction shows alternative splicing of Bin1 and c-Myc phosphorylation are key binding determinants.
J.Mol.Biol., 351, 2005
1EGI
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BU of 1egi by Molmil
STRUCTURE OF A C-TYPE CARBOHYDRATE-RECOGNITION DOMAIN (CRD-4) FROM THE MACROPHAGE MANNOSE RECEPTOR
Descriptor: CALCIUM ION, MACROPHAGE MANNOSE RECEPTOR
Authors:Feinberg, H, Park-Snyder, S, Kolatkar, A.R, Heise, C.T, Taylor, M.E, Weis, W.I.
Deposit date:2000-02-15
Release date:2000-08-30
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of a C-type carbohydrate recognition domain from the macrophage mannose receptor.
J.Biol.Chem., 275, 2000
1MV0
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BU of 1mv0 by Molmil
NMR STRUCTURE OF THE TUMOR SUPPRESSOR BIN1: ALTERNATIVE SPLICING IN MELANOMA AND INTERACTION WITH C-MYC
Descriptor: Myc box-dependent-interacting protein 1, Myc proto-oncogene protein
Authors:Pineda-Lucena, A, Arrowsmith, C.H.
Deposit date:2002-09-24
Release date:2003-09-30
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:A structure-based model of the c-Myc/Bin1 protein interaction shows alternative splicing of Bin1 and c-Myc phosphorylation are key binding determinants.
J.Mol.Biol., 351, 2005
2AVF
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BU of 2avf by Molmil
Crystal Structure of C-terminal Desundecapeptide Nitrite Reductase from Achromobacter cycloclastes
Descriptor: CHLORIDE ION, COPPER (II) ION, Copper-containing nitrite reductase
Authors:Li, H.T, Chang, T, Chang, W.C, Chen, C.J, Liu, M.Y, Gui, L.L, Zhang, J.P, An, X.M, Chang, W.R.
Deposit date:2005-08-30
Release date:2005-12-20
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of C-terminal desundecapeptide nitrite reductase from Achromobacter cycloclastes
Biochem.Biophys.Res.Commun., 338, 2005
3FRY
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BU of 3fry by Molmil
Crystal structure of the CopA C-terminal metal binding domain
Descriptor: CITRIC ACID, Probable copper-exporting P-type ATPase A
Authors:Agarwal, S, Sazinsky, M, Arguello, J, Rosenzweig, A.C.
Deposit date:2009-01-08
Release date:2010-01-12
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure and interactions of the C-terminal metal binding domain of Archaeoglobus fulgidus CopA.
Proteins, 78, 2010
3O8I
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BU of 3o8i by Molmil
Structure of 14-3-3 isoform sigma in complex with a C-Raf1 peptide and a stabilizing small molecule fragment
Descriptor: 14-3-3 binding site peptide of RAF proto-oncogene serine/threonine-protein kinase, 14-3-3 protein sigma, 6,6-dihydroxy-1-methoxyhexan-2-one
Authors:Ottmann, C, Rose, R, Kaiser, M, Kuhenne, P.
Deposit date:2010-08-03
Release date:2010-09-29
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Impaired Binding of 14-3-3 to C-RAF in Noonan Syndrome Suggests New Approaches in Diseases with Increased Ras Signaling
Mol.Cell.Biol., 30, 2010
2OCC
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BU of 2occ by Molmil
BOVINE HEART CYTOCHROME C OXIDASE AT THE FULLY OXIDIZED STATE
Descriptor: COPPER (II) ION, CYTOCHROME C OXIDASE, HEME-A, ...
Authors:Tsukihara, T, Yao, M.
Deposit date:1998-05-26
Release date:1999-01-13
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Redox-coupled crystal structural changes in bovine heart cytochrome c oxidase.
Science, 280, 1998
1LBK
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BU of 1lbk by Molmil
Crystal structure of a recombinant glutathione transferase, created by replacing the last seven residues of each subunit of the human class pi isoenzyme with the additional C-terminal helix of human class alpha isoenzyme
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLUTATHIONE, Glutathione S-transferase class pi chimaera (CODA), ...
Authors:Kong, G.K.W, Micaloni, C, Mazzetti, A.P, Nuccetelli, M, Antonini, G, Stella, L, McKinstry, W.J, Polekhina, G, Rossjohn, J, Federici, G, Ricci, G, Parker, M.W, Lo Bello, M.
Deposit date:2002-04-04
Release date:2002-04-17
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Engineering a new C-terminal tail in the H-site of human glutathione transferase P1-1: structural and functional consequences.
J.Mol.Biol., 325, 2003

238582

數據於2025-07-09公開中

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