1TDB
STRUCTURES OF THYMIDYLATE SYNTHASE WITH A C-TERMINAL DELETION: ROLE OF THE C-TERMINUS IN ALIGNMENT OF D/UMP AND CH2H4FOLATE
Summary for 1TDB
Entry DOI | 10.2210/pdb1tdb/pdb |
Descriptor | THYMIDYLATE SYNTHASE, 5-FLUORO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE (3 entities in total) |
Functional Keywords | transferase (methyltransferase) |
Biological source | Lactobacillus casei |
Cellular location | Cytoplasm: P00469 |
Total number of polymer chains | 1 |
Total formula weight | 36857.50 |
Authors | Perry, K.M.,Carreras, C.W.,Chang, L.C.,Santi, D.V.,Stroud, R.M. (deposition date: 1993-02-15, release date: 1993-07-15, Last modification date: 2024-02-14) |
Primary citation | Perry, K.M.,Carreras, C.W.,Chang, L.C.,Santi, D.V.,Stroud, R.M. Structures of thymidylate synthase with a C-terminal deletion: role of the C-terminus in alignment of 2'-deoxyuridine 5'-monophosphate and 5,10-methylenetetrahydrofolate. Biochemistry, 32:7116-7125, 1993 Cited by PubMed: 8343503DOI: 10.1021/bi00079a007 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.65 Å) |
Structure validation
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