4NIG
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4NJN
| Crystal Structure of E.coli GlpG at pH 4.5 | Descriptor: | Rhomboid protease GlpG | Authors: | Dickey, S.W, Baker, R.P, Cho, S, Urban, S. | Deposit date: | 2013-11-11 | Release date: | 2013-12-25 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Proteolysis inside the Membrane Is a Rate-Governed Reaction Not Driven by Substrate Affinity. Cell(Cambridge,Mass.), 155, 2013
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4NI1
| Quaternary R CO-liganded hemoglobin structure in complex with a thiol containing compound | Descriptor: | 5-[(2R)-2,3-dihydro-1,4-benzodioxin-2-yl]-2,4-dihydro-3H-1,2,4-triazole-3-thione, CARBON MONOXIDE, Hemoglobin subunit alpha, ... | Authors: | Safo, M.K, Meadows, J, Ko, T.-P, Nakagawa, A, Zapol, W. | Deposit date: | 2013-11-05 | Release date: | 2014-09-17 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Identification of a Small Molecule that Increases Hemoglobin Oxygen Affinity and Reduces SS Erythrocyte Sickling. Acs Chem.Biol., 9, 2014
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4NID
| Crystal structure of AlkB protein with cofactors bound to dsDNA containing m6A | Descriptor: | 2-OXOGLUTARIC ACID, 5'-D(*AP*AP*CP*GP*GP*TP*AP*TP*TP*AP*CP*CP*T)-3', 5'-D(*TP*AP*GP*GP*TP*AP*AP*(6MA)P*AP*CP*CP*GP*T)-3', ... | Authors: | Zhu, C.X, Yi, C.Q. | Deposit date: | 2013-11-06 | Release date: | 2014-04-16 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | Switching Demethylation Activities between AlkB Family RNA/DNA Demethylases through Exchange of Active-Site Residues. Angew.Chem.Int.Ed.Engl., 53, 2014
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4P8Q
| Crystal Structure of Human Insulin Regulated Aminopeptidase with Alanine in Active Site | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Leucyl-cystinyl aminopeptidase, ... | Authors: | Hermans, S.J, Ascher, D.B, Hancock, N.C, Holien, J.K, Michell, B, Morton, C.J, Parker, M.W. | Deposit date: | 2014-03-31 | Release date: | 2014-12-03 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (3.02 Å) | Cite: | Crystal structure of human insulin-regulated aminopeptidase with specificity for cyclic peptides. Protein Sci., 24, 2015
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4PHU
| Crystal structure of Human GPR40 bound to allosteric agonist TAK-875 | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, DIMETHYL SULFOXIDE, Free fatty acid receptor 1,Lysozyme, ... | Authors: | Srivastava, A, Yano, J.K, Hirozane, Y, Kefala, G, Snell, G, Lane, W, Gruswitz, F, Ivetac, A, Aertgeerts, K, Nguyen, J, Jennings, A, Okada, K. | Deposit date: | 2014-05-07 | Release date: | 2014-07-16 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.332 Å) | Cite: | High-resolution structure of the human GPR40 receptor bound to allosteric agonist TAK-875. Nature, 513, 2014
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4PKH
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4PEW
| Structure of sacteLam55A from Streptomyces sp. SirexAA-E | Descriptor: | 1,2-ETHANEDIOL, MAGNESIUM ION, Putative secreted protein | Authors: | Bianchetti, C.M, Takasuka, T.E, Bergeman, L.F, Fox, B.G. | Deposit date: | 2014-04-25 | Release date: | 2015-03-18 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.51 Å) | Cite: | Active site and laminarin binding in glycoside hydrolase family 55. J.Biol.Chem., 290, 2015
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4OV5
| Structure of HLA-DR1 with a bound peptide with non-optimal alanine in the P1 pocket | Descriptor: | HLA class I histocompatibility antigen, A-2 alpha chain, HLA class II histocompatibility antigen, ... | Authors: | Trenh, P, Yin, L, Stern, L.J. | Deposit date: | 2014-02-20 | Release date: | 2014-07-16 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.199 Å) | Cite: | Susceptibility to HLA-DM Protein Is Determined by a Dynamic Conformation of Major Histocompatibility Complex Class II Molecule Bound with Peptide. J.Biol.Chem., 289, 2014
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4OXF
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4OQ6
| Crystal Structure of Human MCL-1 Bound to Inhibitor 4-hydroxy-4'-propylbiphenyl-3-carboxylic acid | Descriptor: | 4-hydroxy-4'-propylbiphenyl-3-carboxylic acid, Induced myeloid leukemia cell differentiation protein Mcl-1 | Authors: | Petros, A.M, Swann, S.L, Song, D, Swinger, K, Park, C, Zhang, H, Wendt, M.D, Kunzer, A.R, Souers, A.J, Sun, C. | Deposit date: | 2014-02-07 | Release date: | 2014-03-12 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.81 Å) | Cite: | Fragment-based discovery of potent inhibitors of the anti-apoptotic MCL-1 protein. Bioorg.Med.Chem.Lett., 24, 2014
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4OE4
| Crystal Structure of Yeast ALDH4A1 Complexed with NAD+ | Descriptor: | Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | Authors: | Tanner, J.J. | Deposit date: | 2014-01-11 | Release date: | 2014-02-19 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.168 Å) | Cite: | Structural Studies of Yeast Delta (1)-Pyrroline-5-carboxylate Dehydrogenase (ALDH4A1): Active Site Flexibility and Oligomeric State. Biochemistry, 53, 2014
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4OL9
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4OH3
| Crystal structure of a nitrate transporter | Descriptor: | DODECYL-BETA-D-MALTOSIDE, NITRATE ION, Nitrate transporter 1.1 | Authors: | Sun, J, Bankston, J.R, Payandeh, J, Hinds, T.R, Zagotta, W.N, Zheng, N. | Deposit date: | 2014-01-16 | Release date: | 2014-03-05 | Last modified: | 2014-03-12 | Method: | X-RAY DIFFRACTION (3.25 Å) | Cite: | Crystal structure of the plant dual-affinity nitrate transporter NRT1.1. Nature, 507, 2014
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4PKI
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4PJ0
| Structure of T.elongatus Photosystem II, rows of dimers crystal packing | Descriptor: | 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, ... | Authors: | Hellmich, J, Bommer, M, Burkhardt, A, Ibrahim, M, Kern, J, Meents, A, Mueh, F, Dobbek, H, Zouni, A. | Deposit date: | 2014-05-10 | Release date: | 2014-10-22 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.437 Å) | Cite: | Native-like Photosystem II Superstructure at 2.44 angstrom Resolution through Detergent Extraction from the Protein Crystal. Structure, 22, 2014
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4PKG
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4PEX
| Structure of the E502A variant of sacteLam55A from Streptomyces sp. SirexAA-E in complex with glucose | Descriptor: | 1,2-ETHANEDIOL, Putative secreted protein, beta-D-glucopyranose | Authors: | Bianchetti, C.M, Takasuka, T.E, Yik, E.J, Bergeman, L.F, Fox, B.G. | Deposit date: | 2014-04-25 | Release date: | 2015-03-18 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Active site and laminarin binding in glycoside hydrolase family 55. J.Biol.Chem., 290, 2015
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4O79
| Crystal Structure of Ascorbate-bound Cytochrome b561, crystal soaked in 1 M L-ascorbate for 10 minutes | Descriptor: | ASCORBIC ACID, PROTOPORPHYRIN IX CONTAINING FE, Probable transmembrane ascorbate ferrireductase 2, ... | Authors: | Lu, P, Ma, D, Yan, C, Gong, X, Du, M, Shi, Y. | Deposit date: | 2013-12-24 | Release date: | 2014-02-05 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.003 Å) | Cite: | Structure and mechanism of a eukaryotic transmembrane ascorbate-dependent oxidoreductase Proc.Natl.Acad.Sci.USA, 111, 2014
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4OE6
| Crystal Structure of Yeast ALDH4A1 | Descriptor: | Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial | Authors: | Tanner, J.J. | Deposit date: | 2014-01-11 | Release date: | 2014-02-19 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.951 Å) | Cite: | Structural Studies of Yeast Delta (1)-Pyrroline-5-carboxylate Dehydrogenase (ALDH4A1): Active Site Flexibility and Oligomeric State. Biochemistry, 53, 2014
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4ONC
| Crystal Structure of Mycobacterium Tuberculosis Decaprenyl Diphosphate Synthase in Complex with BPH-640 | Descriptor: | Decaprenyl diphosphate synthase, [hydroxy(1,1':3',1''-terphenyl-3-yl)methanediyl]bis(phosphonic acid) | Authors: | Feng, X, Chan, H.C, Ko, T.P. | Deposit date: | 2014-01-28 | Release date: | 2014-04-02 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | Structure and Inhibition of Tuberculosinol Synthase and Decaprenyl Diphosphate Synthase from Mycobacterium tuberculosis J.Am.Chem.Soc., 136, 2014
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4OU3
| Crystal structure of porcine aminopeptidase N complexed with CNGRCG tumor-homing peptide | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Aminopeptidase N, ... | Authors: | Liu, C, Yang, Y, Chen, L, Lin, Y.-L, Li, F. | Deposit date: | 2014-02-14 | Release date: | 2014-11-05 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | A Unified Mechanism for Aminopeptidase N-based Tumor Cell Motility and Tumor-homing Therapy. J.Biol.Chem., 289, 2014
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4OR5
| Crystal structure of HIV-1 Tat complexed with human P-TEFb and AFF4 | Descriptor: | AF4/FMR2 family member 4, Cyclin-T1, Cyclin-dependent kinase 9, ... | Authors: | Gu, J, Babayeva, N.D, Suwa, Y, Baranovskiy, A.G, Price, D.H, Tahirov, T.H. | Deposit date: | 2014-02-10 | Release date: | 2014-04-16 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal structure of HIV-1 Tat complexed with human P-TEFb and AFF4. Cell Cycle, 13, 2014
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4NFL
| Crystal structure of human mitochondrial 5'(3')-deoxyribonucleotidase in complex with the inhibitor NPB-T | Descriptor: | 1-{2-deoxy-3,5-O-[(4-nitrophenyl)(phosphono)methylidene]-beta-D-threo-pentofuranosyl}-5-methylpyrimidine-2,4(1H,3H)-dione, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5'(3')-deoxyribonucleotidase, ... | Authors: | Pachl, P, Rezacova, P, Brynda, J. | Deposit date: | 2013-10-31 | Release date: | 2014-09-10 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.375 Å) | Cite: | Conformationally constrained nucleoside phosphonic acids - potent inhibitors of human mitochondrial and cytosolic 5'(3')-nucleotidases. Org.Biomol.Chem., 12, 2014
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4NO4
| Crystal Structure of Galectin-1 L11A mutant | Descriptor: | GLYCEROL, Galectin-1, MAGNESIUM ION, ... | Authors: | Dessau, M. | Deposit date: | 2013-11-19 | Release date: | 2014-12-03 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.399 Å) | Cite: | Crystal Structure of Galectin-1 L11A mutant To be Published
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