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5NDG
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BU of 5ndg by Molmil
Crystal structure of geneticin (G418) bound to the yeast 80S ribosome
Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
Authors:Prokhorova, I, Djumagulov, M, Urzhumtsev, A, Yusupov, M, Yusupova, G.
Deposit date:2017-03-08
Release date:2017-12-13
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Aminoglycoside interactions and impacts on the eukaryotic ribosome.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5V1Z
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BU of 5v1z by Molmil
Crystal structure of the RPN13 PRU-RPN2 (932-953)-ubiquitin complex
Descriptor: 26S proteasome non-ATPase regulatory subunit 1, Proteasomal ubiquitin receptor ADRM1, Ubiquitin
Authors:Hemmis, C.W, VanderLinden, R.T, Yao, T, Robinson, H, Hill, C.P.
Deposit date:2017-03-02
Release date:2017-05-03
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure and energetics of pairwise interactions between proteasome subunits RPN2, RPN13, and ubiquitin clarify a substrate recruitment mechanism.
J. Biol. Chem., 292, 2017
5V1Y
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BU of 5v1y by Molmil
Crystal structure of the ternary RPN13 PRU-RPN2 (940-953)-ubiquitin complex
Descriptor: 26S proteasome non-ATPase regulatory subunit 1, Proteasomal ubiquitin receptor ADRM1, Ubiquitin
Authors:Hemmis, C.W, VanderLinden, R.T, Yao, T, Robinson, H, Hill, C.P.
Deposit date:2017-03-02
Release date:2017-05-03
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.421 Å)
Cite:Structure and energetics of pairwise interactions between proteasome subunits RPN2, RPN13, and ubiquitin clarify a substrate recruitment mechanism.
J. Biol. Chem., 292, 2017
5N9V
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BU of 5n9v by Molmil
NMR solution structure of ubl5 domain from polyubiquitin locus of T.thermophila.
Descriptor: NAD(P)(+)--arginine ADP-ribosyltransferase
Authors:Chiarini, V, Tossavainen, H.
Deposit date:2017-02-27
Release date:2018-03-21
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:NMR structure of a non-conjugatable, ADP-ribosylation associated, ubiquitin-like domain from Tetrahymena thermophila polyubiquitin locus.
Biochim Biophys Acta Gen Subj, 1863, 2019
5N4W
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BU of 5n4w by Molmil
Crystal structure of the Cul2-Rbx1-EloBC-VHL ubiquitin ligase complex
Descriptor: Cullin-2, E3 ubiquitin-protein ligase RBX1, Elongin-B, ...
Authors:Cardote, T.A.F, Gadd, M.S, Ciulli, A.
Deposit date:2017-02-11
Release date:2017-06-07
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Crystal Structure of the Cul2-Rbx1-EloBC-VHL Ubiquitin Ligase Complex.
Structure, 25, 2017
5N38
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BU of 5n38 by Molmil
S65DParkin and pUB complex
Descriptor: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, E3 ubiquitin-protein ligase parkin,E3 ubiquitin-protein ligase parkin, ...
Authors:Kumar, A, Chaugule, V.K, Johnson, C, Toth, R, Sundaramoorthy, R, Knebel, A, Walden, H.
Deposit date:2017-02-08
Release date:2017-04-19
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Parkin-phosphoubiquitin complex reveals cryptic ubiquitin-binding site required for RBR ligase activity.
Nat. Struct. Mol. Biol., 24, 2017
5N2W
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BU of 5n2w by Molmil
WT-Parkin and pUB complex
Descriptor: CHLORIDE ION, E3 ubiquitin-protein ligase parkin,E3 ubiquitin-protein ligase parkin, Polyubiquitin-B, ...
Authors:Kumar, A, Chaugule, V.K, Johnson, C, Toth, R, Sundaramoorthy, R, Knebel, A, Walden, H.
Deposit date:2017-02-08
Release date:2017-04-19
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:Parkin-phosphoubiquitin complex reveals cryptic ubiquitin-binding site required for RBR ligase activity.
Nat. Struct. Mol. Biol., 24, 2017
5X3O
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BU of 5x3o by Molmil
Crystal structure of p-DiUb-S65-COOH
Descriptor: D-ubiquitin, Polyubiquitin-B
Authors:Man, P, Shuai, G, Qian, Q, Lei, L.
Deposit date:2017-02-06
Release date:2017-04-12
Last modified:2022-02-09
Method:X-RAY DIFFRACTION (2.194 Å)
Cite:Structure of p-DiUb-S65-COOH at 2.19 Angstroms resolution.
To Be Published
5X3N
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BU of 5x3n by Molmil
Crystal structure of DiUb-K6
Descriptor: PHOSPHATE ION, Polyubiquitin-B
Authors:Man, P, Shuai, G, Qian, Q, Lei, L.
Deposit date:2017-02-06
Release date:2017-04-12
Method:X-RAY DIFFRACTION (1.649 Å)
Cite:Structure of p-Ub-S65-NH2 at 1.82 Angstroms resolution.
To Be Published
5X3M
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BU of 5x3m by Molmil
crystal structure of p-Ub-S65-NH2
Descriptor: D-ubiquitin, Polyubiquitin-B
Authors:Man, P, Shuai, G, Qian, Q, Lei, L.
Deposit date:2017-02-06
Release date:2017-04-05
Last modified:2022-02-09
Method:X-RAY DIFFRACTION (1.818 Å)
Cite:Structure of p-Ub-S65-NH2 at 1.82 Angstroms resolution
To Be Published
5UMD
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BU of 5umd by Molmil
Structure of the Plasmodium falciparum 80S ribosome bound to the antimalarial drug mefloquine
Descriptor: 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Wong, W, Bai, X.-C, Brown, A, Scheres, S, Baum, J.
Deposit date:2017-01-27
Release date:2017-03-01
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Mefloquine targets the Plasmodium falciparum 80S ribosome to inhibit protein synthesis.
Nat Microbiol, 2, 2017
5ULK
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BU of 5ulk by Molmil
Crystal Structure of RNF165 in complex with a UbcH5b~Ub conjugate
Descriptor: E3 ubiquitin-protein ligase RNF165, Ubiquitin, Ubiquitin-conjugating enzyme E2 D2, ...
Authors:Middleton, A.J, Day, C.L, Wright, J.D.
Deposit date:2017-01-24
Release date:2017-06-07
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Discovery of new non-covalent ubiquitin binding sites on UbcH5
To be published
5ULH
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BU of 5ulh by Molmil
Structure of RNF165 in complex with a UbcH5b~Ub conjugate
Descriptor: E3 ubiquitin-protein ligase RNF165, GLYCEROL, THIOCYANATE ION, ...
Authors:Middleton, A.J, Day, C.L, Wright, J.D.
Deposit date:2017-01-24
Release date:2017-06-07
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Discovery of new non-covalent ubiquitin binding sites on UbcH5
To be published
5ULF
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BU of 5ulf by Molmil
Crystal Structure of a UbcH5b~Ub conjugate
Descriptor: GLYCEROL, Ubiquitin, Ubiquitin-conjugating enzyme E2 D2
Authors:Middleton, A.J, Day, C.L, Wright, J.D.
Deposit date:2017-01-24
Release date:2017-06-07
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Discovery of new non-covalent ubiquitin binding sites on UbcH5
To be published
5UJL
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BU of 5ujl by Molmil
Representative 1-conformer ensembles of K27-linked Ub2 from RDC data
Descriptor: Ubiquitin
Authors:Castaneda, C.A, Fushman, D.
Deposit date:2017-01-18
Release date:2017-10-25
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Linkage via K27 Bestows Ubiquitin Chains with Unique Properties among Polyubiquitins.
Structure, 24, 2016
5UJN
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BU of 5ujn by Molmil
Representative 2-conformer ensembles of K27-linked Ub2 from RDC data
Descriptor: Ubiquitin
Authors:Castaneda, C.A, Fushman, D.
Deposit date:2017-01-18
Release date:2018-08-08
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Linkage via K27 Bestows Ubiquitin Chains with Unique Properties among Polyubiquitins.
Structure, 24, 2016
5WYJ
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BU of 5wyj by Molmil
Cryo-EM structure of the 90S small subunit pre-ribosome (Dhr1-depleted, Enp1-TAP, state 1)
Descriptor: 13 kDa ribonucleoprotein-associated protein, 18S ribosomal RNA, 40S ribosomal protein S1-A, ...
Authors:Ye, K, Zhu, X, Sun, Q.
Deposit date:2017-01-13
Release date:2017-03-29
Last modified:2019-10-09
Method:ELECTRON MICROSCOPY (8.7 Å)
Cite:Molecular architecture of the 90S small subunit pre-ribosome.
Elife, 6, 2017
5WVO
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BU of 5wvo by Molmil
Crystal structure of DNMT1 RFTS domain in complex with K18/K23 mono-ubiquitylated histone H3
Descriptor: DNA (cytosine-5)-methyltransferase 1, Histone H3.1, Ubiquitin, ...
Authors:Ishiyama, S, Nishiyama, A, Nakanishi, M, Arita, K.
Deposit date:2016-12-28
Release date:2017-11-15
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.997 Å)
Cite:Structure of the Dnmt1 Reader Module Complexed with a Unique Two-Mono-Ubiquitin Mark on Histone H3 Reveals the Basis for DNA Methylation Maintenance
Mol. Cell, 68, 2017
5UDH
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BU of 5udh by Molmil
HHARI/ARIH1-UBCH7~Ubiquitin
Descriptor: E3 ubiquitin-protein ligase ARIH1, Ubiquitin C variant, Ubiquitin-conjugating enzyme E2 L3, ...
Authors:Miller, D.J, Schulman, B.A.
Deposit date:2016-12-27
Release date:2017-06-14
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (3.24 Å)
Cite:Structural Studies of HHARI/UbcH7Ub Reveal Unique E2Ub Conformational Restriction by RBR RING1.
Structure, 25, 2017
5MN9
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BU of 5mn9 by Molmil
Crystal structure of MINDY-1 tMIU in complex with K48-diUb
Descriptor: Ubiquitin carboxyl-terminal hydrolase MINDY-1, Ubiquitin-40S ribosomal protein S27a
Authors:Kristariyanto, Y.A, Abdul Rehman, S.A, Kulathu, Y.
Deposit date:2016-12-13
Release date:2017-01-25
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:A single MIU motif of MINDY-1 recognizes K48-linked polyubiquitin chains.
EMBO Rep., 18, 2017
5MNJ
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BU of 5mnj by Molmil
Structure of MDM2-MDMX-UbcH5B-ubiquitin complex
Descriptor: E3 ubiquitin-protein ligase Mdm2, Polyubiquitin-B, Protein Mdm4, ...
Authors:Klejnot, M, Huang, D.T.
Deposit date:2016-12-13
Release date:2017-05-31
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Structural analysis of MDM2 RING separates degradation from regulation of p53 transcription activity.
Nat. Struct. Mol. Biol., 24, 2017
5U4P
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BU of 5u4p by Molmil
Protein-protein complex between 26S proteasome regulatory subunit RPN8, RPN11, and Ubiquitin S31
Descriptor: 26S proteasome regulatory subunit RPN11, 26S proteasome regulatory subunit RPN8, Ubiquitin-40S ribosomal protein S31, ...
Authors:Worden, E.J, Dong, K.C, Martin, A.
Deposit date:2016-12-05
Release date:2017-09-06
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:An AAA Motor-Driven Mechanical Switch in Rpn11 Controls Deubiquitination at the 26S Proteasome.
Mol. Cell, 67, 2017
5WQ4
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BU of 5wq4 by Molmil
Crystal structure of OPTN and linear diubiquitin complex
Descriptor: Optineurin, ubiquitin
Authors:Li, F, Pan, L.
Deposit date:2016-11-23
Release date:2017-12-06
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural insights into the ubiquitin recognition by OPTN (optineurin) and its regulation by TBK1-mediated phosphorylation.
Autophagy, 14, 2018
5H7S
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BU of 5h7s by Molmil
Structural basis of the flanking zinc-finger motifs crucial for the E3 ligase activity of the LNX1 RING domain
Descriptor: E3 ubiquitin-protein ligase LNX, Ubiquitin-conjugating enzyme E2 N, Ubiquitin-like 1, ...
Authors:Nayak, D, Sivaraman, J.
Deposit date:2016-11-21
Release date:2017-11-29
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.49 Å)
Cite:Structure of LNX1:Ubc13~Ubiquitin Complex Reveals the Role of Additional Motifs for the E3 Ligase Activity of LNX1.
J. Mol. Biol., 430, 2018
5TXK
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BU of 5txk by Molmil
CRYSTAL STRUCTURE OF USP35 C450S IN COMPLEX WITH UBIQUITIN
Descriptor: 1,2-ETHANEDIOL, Polyubiquitin-B, SULFATE ION, ...
Authors:Bader, G, Weiss-Puxbaum, A, Zoephel, A.
Deposit date:2016-11-17
Release date:2018-05-09
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Expansion of DUB functionality generated by alternative isoforms - USP35, a case study.
J. Cell. Sci., 131, 2018

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數據於2024-06-26公開中

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