7TYZ
| Cryo-EM structure of SARS-CoV-2 spike in complex with FSR22, an anti-SARS-CoV-2 DARPin | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DARPin FSR22, ... | Authors: | Kwon, Y.D, Gorman, J, Kwong, P.D. | Deposit date: | 2022-02-15 | Release date: | 2022-12-07 | Last modified: | 2023-03-15 | Method: | ELECTRON MICROSCOPY (3.51 Å) | Cite: | A potent and broad neutralization of SARS-CoV-2 variants of concern by DARPins. Nat.Chem.Biol., 19, 2023
|
|
7TPK
| |
7U0Q
| |
7U0X
| |
7TPI
| SARS-CoV-2 E406W mutant Spike ectodomain | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | Authors: | Addetia, A, Veesler, D. | Deposit date: | 2022-01-25 | Release date: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (2.3 Å) | Cite: | SARS-CoV-2 E406W mutant Spike ectodomain To Be Published
|
|
7UHB
| |
7UB0
| |
7UB5
| |
7UB6
| |
7UAP
| |
7UAR
| |
7UAQ
| Structure of the SARS-CoV-2 NTD in complex with C1520, local refinement | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C1520 Fab Heavy Chain, ... | Authors: | Barnes, C.O. | Deposit date: | 2022-03-13 | Release date: | 2022-04-27 | Last modified: | 2024-10-16 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Analysis of memory B cells identifies conserved neutralizing epitopes on the N-terminal domain of variant SARS-Cov-2 spike proteins. Immunity, 55, 2022
|
|
7URS
| |
7URQ
| |
7UFL
| Crystal structure of chimeric omicron RBD (strain BA.2) complexed with chimeric mouse ACE2 | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Zhang, W, Shi, K, Geng, Q, Ye, G, Aihara, H, Li, F. | Deposit date: | 2022-03-22 | Release date: | 2022-10-19 | Last modified: | 2024-10-23 | Method: | X-RAY DIFFRACTION (2.84 Å) | Cite: | Structural basis for mouse receptor recognition by SARS-CoV-2 omicron variant. Proc.Natl.Acad.Sci.USA, 119, 2022
|
|
7UPL
| SARS-Cov2 Omicron varient S protein structure in complex with neutralizing monoclonal antibody 002-S21F2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | Authors: | Patel, A, Ortlund, E. | Deposit date: | 2022-04-15 | Release date: | 2022-08-10 | Last modified: | 2024-10-09 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Structural insights for neutralization of Omicron variants BA.1, BA.2, BA.4, and BA.5 by a broadly neutralizing SARS-CoV-2 antibody. Sci Adv, 8, 2022
|
|
7UPX
| Three RBD-down state of SARS-CoV-2 D614G spike in complex with the SP1-77 neutralizing antibody Fab fragment (local refinement of the RBD and Fab variable domains) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, SP1-77 Fab heavy chain, SP1-77 Fab light chain, ... | Authors: | Zhang, J, Luo, S, Kreutzberger, A, Kirchhausen, T, Chen, B, Haynes, B, Alt, F. | Deposit date: | 2022-04-18 | Release date: | 2022-08-10 | Last modified: | 2024-10-09 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | An antibody from single human V H -rearranging mouse neutralizes all SARS-CoV-2 variants through BA.5 by inhibiting membrane fusion. Sci Immunol, 7, 2022
|
|
7UPY
| An antibody from single human VH-rearranging mouse neutralizes all SARS-CoV-2 variants through BA.5 by inhibiting membrane fusion | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Zhang, J, Luo, S, Kreutzberger, A, Kirchhausen, T, Chen, B, Haynes, B, Alt, F. | Deposit date: | 2022-04-18 | Release date: | 2022-08-10 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | An antibody from single human V H -rearranging mouse neutralizes all SARS-CoV-2 variants through BA.5 by inhibiting membrane fusion. Sci Immunol, 7, 2022
|
|
7UPW
| Three RBD-down state of SARS-CoV-2 D614G spike in complex with the SP1-77 neutralizing antibody Fab fragment | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Zhang, J, Luo, S, Kreutzberger, A, Kirchhausen, T, Chen, B, Haynes, B, Alt, F. | Deposit date: | 2022-04-18 | Release date: | 2022-08-10 | Last modified: | 2024-10-30 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | An antibody from single human V H -rearranging mouse neutralizes all SARS-CoV-2 variants through BA.5 by inhibiting membrane fusion. Sci Immunol, 7, 2022
|
|
7U9O
| SARS-CoV-2 spike trimer RBD in complex with Fab NE12 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, NE12 Fab heavy chain, NE12 Fab light chain, ... | Authors: | Tsybovsky, Y, Kwong, P.D, Farci, P. | Deposit date: | 2022-03-11 | Release date: | 2022-11-23 | Last modified: | 2024-10-23 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Potent monoclonal antibodies neutralize Omicron sublineages and other SARS-CoV-2 variants. Cell Rep, 41, 2022
|
|
7U9P
| SARS-CoV-2 spike trimer RBD in complex with Fab NA8 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, NA8 Fab heavy chain, NA8 Fab light chain, ... | Authors: | Tsybovsky, Y, Kwong, P.D, Farci, P. | Deposit date: | 2022-03-11 | Release date: | 2022-11-23 | Last modified: | 2024-11-06 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Potent monoclonal antibodies neutralize Omicron sublineages and other SARS-CoV-2 variants. Cell Rep, 41, 2022
|
|
7UZ9
| |
7UZ8
| |
7UZA
| |
7UZ5
| |