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1KHC
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Crystal Structure of the PWWP Domain of Mammalian DNA Methyltransferase Dnmt3b
Descriptor: DNA cytosine-5 methyltransferase 3B2, UNKNOWN ATOM OR ION
Authors:Qiu, C, Sawada, K, Zhang, X, Cheng, X.
Deposit date:2001-11-29
Release date:2002-02-27
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The PWWP domain of mammalian DNA methyltransferase Dnmt3b defines a new family of DNA-binding folds.
Nat.Struct.Biol., 9, 2002
1KHI
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BU of 1khi by Molmil
CRYSTAL STRUCTURE OF HEX1
Descriptor: Hex1
Authors:Yuan, P, Swaminathan, K.
Deposit date:2001-11-30
Release date:2002-11-30
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:A HEX-1 crystal lattice required for Woronin body function in Neurospora crassa
NAT.STRUCT.BIOL., 10, 2003
5I5S
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BU of 5i5s by Molmil
X-RAY CRYSTAL STRUCTURE AT 2.06A RESOLUTION OF HUMAN MITOCHONDRIAL BRANCHED CHAIN AMINOTRANSFERASE (BCATM) COMPLEXED WITH A BENZISOXAZOLE COMPOUND AND AN INTERNAL ALDIMINE LINKED PLP COFACTOR.
Descriptor: 1,2-ETHANEDIOL, 2-(1,2-benzoxazol-3-yl)ethanoic acid, Branched-chain-amino-acid aminotransferase, ...
Authors:Somers, D.
Deposit date:2016-02-15
Release date:2016-03-23
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Structurally Diverse Mitochondrial Branched Chain Aminotransferase (BCATm) Leads with Varying Binding Modes Identified by Fragment Screening.
J.Med.Chem., 59, 2016
1KHG
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PEPCK
Descriptor: 1,2-ETHANEDIOL, MANGANESE (II) ION, Phosphoenolpyruvate carboxykinase, ...
Authors:Dunten, P, Belunis, C, Crowther, R, Hollfelder, K, Kammlott, U, Levin, W, Michel, H, Ramsey, G.B, Swain, A, Weber, D, Wertheimer, S.J.
Deposit date:2001-11-29
Release date:2002-02-27
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Crystal structure of human cytosolic phosphoenolpyruvate carboxykinase reveals a new GTP-binding site.
J.Mol.Biol., 316, 2002
1KHO
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Crystal Structure Analysis of Clostridium perfringens alpha-Toxin Isolated from Avian Strain SWCP
Descriptor: ZINC ION, alpha-toxin
Authors:Justin, N, Moss, D.S, Titball, R.W, Basak, A.K.
Deposit date:2001-11-30
Release date:2002-06-19
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The first strain of Clostridium perfringens isolated from an avian source has an alpha-toxin with divergent structural and kinetic properties.
Biochemistry, 41, 2002
1KR4
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Structure Genomics, Protein TM1056, cutA
Descriptor: Protein TM1056, cutA
Authors:Savchenko, A, Zhang, R, Joachimiak, A, Edwards, A, Akarina, T, Midwest Center for Structural Genomics (MCSG)
Deposit date:2002-01-08
Release date:2002-08-14
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:X-ray crystal structure of CutA from Thermotoga maritima at 1.4 A resolution.
Proteins, 54, 2004
1KR8
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Refinement of d(GCGAAGC) Hairpin Structure Using One-and Two-Bonds Residual Dipolar Couplings
Descriptor: 5'-D(*GP*CP*GP*AP*AP*GP*C)-3'
Authors:Padrta, P, Stefl, R, Zidek, L, Sklenar, V.
Deposit date:2002-01-09
Release date:2002-12-11
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Refinement of d(GCGAAGC) Hairpin Structure Using One- and Two-Bond Residual Dipolar Couplings
J.BIOMOL.NMR, 24, 2002
1KRL
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Crystal Structure of Racemic DL-monellin in P-1
Descriptor: MONELLIN, CHAIN A, CHAIN B
Authors:Hung, L.W, Kohmura, M, Ariyoshi, Y, Kim, S.H.
Deposit date:2002-01-10
Release date:2002-02-27
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural differences in D and L-monellin in the crystals of racemic mixture.
J.Mol.Biol., 285, 1999
1KRO
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Thermolysin complexed with Z-D-Threonine (benzyloxycarbonyl-D-Threonine)
Descriptor: CALCIUM ION, D-THREONINE, Thermolysin, ...
Authors:Senda, M, Senda, T, Kidokoro, S.
Deposit date:2002-01-10
Release date:2003-01-10
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure analyses of thermolysin in complex with its inhibitors.
To be Published
1KHU
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Smad1 crystal structure reveals the details of BMP signaling pathway
Descriptor: SMAD1
Authors:Qin, B.Y, Lin, K.
Deposit date:2001-12-01
Release date:2001-12-12
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis of Smad1 activation by receptor kinase phosphorylation.
Mol.Cell, 8, 2001
1KI0
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The X-ray Structure of Human Angiostatin
Descriptor: ANGIOSTATIN, BICINE
Authors:Abad, M.C, Arni, R.K, Grella, D.K, Castellino, F.J, Tulinsky, A, Geiger, J.H.
Deposit date:2001-12-02
Release date:2002-05-29
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:The X-ray crystallographic structure of the angiogenesis inhibitor angiostatin.
J.Mol.Biol., 318, 2002
1KHM
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C-TERMINAL KH DOMAIN OF HNRNP K (KH3)
Descriptor: PROTEIN (HNRNP K)
Authors:Baber, J, Libutti, D, Levens, D, Tjandra, N.
Deposit date:1999-01-07
Release date:2000-01-12
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:High precision solution structure of the C-terminal KH domain of heterogeneous nuclear ribonucleoprotein K, a c-myc transcription factor.
J.Mol.Biol., 289, 1999
1KI8
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CRYSTAL STRUCTURE OF THYMIDINE KINASE FROM HERPES SIMPLEX VIRUS TYPE I COMPLEXED WITH 5-BROMOVINYLDEOXYURIDINE
Descriptor: 5-BROMOVINYLDEOXYURIDINE, SULFATE ION, THYMIDINE KINASE
Authors:Champness, J.N, Bennett, M.S, Wien, F, Visse, R, Summers, W.C, Sanderson, M.R.
Deposit date:1998-05-15
Release date:1998-12-02
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Exploring the active site of herpes simplex virus type-1 thymidine kinase by X-ray crystallography of complexes with aciclovir and other ligands.
Proteins, 32, 1998
1KSL
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STRUCTURE OF RSUA
Descriptor: RIBOSOMAL SMALL SUBUNIT PSEUDOURIDINE SYNTHASE A, URACIL
Authors:Sivaraman, J, Sauve, V, Larocque, R, Stura, E.A, Schrag, J.D, Cygler, M, Matte, A, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
Deposit date:2002-01-13
Release date:2002-04-24
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of the 16S rRNA pseudouridine synthase RsuA bound to uracil and UMP.
Nat.Struct.Biol., 9, 2002
1KSV
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BU of 1ksv by Molmil
STRUCTURE OF RSUA
Descriptor: RIBOSOMAL SMALL SUBUNIT PSEUDOURIDINE SYNTHASE A, URIDINE-5'-MONOPHOSPHATE
Authors:Sivaraman, J, Sauve, V, Larocque, R, Stura, E.A, Schrag, J.D, Cygler, M, Matte, A.
Deposit date:2002-01-14
Release date:2002-04-24
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structure of the 16S rRNA pseudouridine synthase RsuA bound to uracil and UMP.
Nat.Struct.Biol., 9, 2002
1KT0
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Structure of the Large FKBP-like Protein, FKBP51, Involved in Steroid Receptor Complexes
Descriptor: 51 KDA FK506-BINDING PROTEIN, SULFATE ION
Authors:Sinars, C.R, Cheung-Flynn, J, Rimerman, R.A, Scammell, J.G, Smith, D.F, Clardy, J.C.
Deposit date:2002-01-14
Release date:2003-02-04
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of the large FK506-binding protein FKBP51, an Hsp90-binding protein and a component of steroid receptor complexes
Proc.Natl.Acad.Sci.USA, 100, 2003
5ICG
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BU of 5icg by Molmil
Crystal structure of apo (S)-norcoclaurine 6-O-methyltransferase
Descriptor: (S)-norcoclaurine 6-O-methyltransferase, POTASSIUM ION
Authors:Robin, A.Y, Graindorge, M, Giustini, C, Dumas, R, Matringe, M.
Deposit date:2016-02-23
Release date:2016-06-08
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of norcoclaurine-6-O-methyltransferase, a key rate-limiting step in the synthesis of benzylisoquinoline alkaloids.
Plant J., 87, 2016
1KTQ
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DNA POLYMERASE
Descriptor: DNA POLYMERASE I
Authors:Korolev, S, Waksman, G.
Deposit date:1995-08-16
Release date:1996-11-08
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the large fragment of Thermus aquaticus DNA polymerase I at 2.5-A resolution: structural basis for thermostability.
Proc.Natl.Acad.Sci.USA, 92, 1995
1KIX
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BU of 1kix by Molmil
Dimeric Structure of the O. nova Telomere End Binding Protein Alpha Subunit with Bound ssDNA
Descriptor: 5'-D(*T*TP*TP*TP*GP*GP*GP*G)-3', SULFATE ION, Telomere-Binding Protein alpha Subunit
Authors:Peersen, O.B, Ruggles, J.A, Schultz, S.C.
Deposit date:2001-12-03
Release date:2002-02-22
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Dimeric structure of the Oxytricha nova telomere end-binding protein alpha-subunit bound to ssDNA.
Nat.Struct.Biol., 9, 2002
1KU9
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X-ray Structure of a Methanococcus jannaschii DNA-Binding Protein: Implications for Antibiotic Resistance in Staphylococcus aureus
Descriptor: hypothetical protein MJ223
Authors:Ray, S.S, Bonanno, J.B, Chen, H, de Lencastre, H, Wu, S, Tomasz, A, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2002-01-21
Release date:2002-12-25
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:X-ray structure of an M. jannaschii DNA-binding protein: implications for antibiotic resistance in S. aureus
Proteins, 50, 2002
6UKX
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STING C-terminal Domain Complexed with Non-cyclic Dinucleotide Compound 11
Descriptor: 4,4'-{propane-1,3-diylbis[oxy(5-methoxy-1-benzothiene-6,2-diyl)]}bis(4-oxobutanoic acid), fusion protein of Ubiquitin-like protein SMT3 and Stimulator of interferon protein c-terminal domain
Authors:Lesburg, C.A.
Deposit date:2019-10-06
Release date:2020-08-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:An orally available non-nucleotide STING agonist with antitumor activity.
Science, 369, 2020
1KUX
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X-ray Crystallographic Studies of Serotonin N-acetyltransferase Catalysis and Inhibition
Descriptor: COA-S-TRIMETHYLENE-ACETYL-TRYPTAMINE, Serotonin N-acetyltransferase
Authors:Wolf, E, De Angelis, J, Khalil, E.M, Cole, P.A, Burley, S.K.
Deposit date:2002-01-22
Release date:2002-03-22
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:X-ray crystallographic studies of serotonin N-acetyltransferase catalysis and inhibition.
J.Mol.Biol., 317, 2002
1KIR
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FV MUTANT Y(A 50)S (VL DOMAIN) OF MOUSE MONOCLONAL ANTIBODY D1.3 COMPLEXED WITH HEN EGG WHITE LYSOZYME
Descriptor: LYSOZYME, MONOCLONAL ANTIBODY D1.3
Authors:Fields, B.A, Poljak, R.J, Mariuzza, R.A.
Deposit date:1996-10-23
Release date:1996-12-23
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:Hydrogen bonding and solvent structure in an antigen-antibody interface. Crystal structures and thermodynamic characterization of three Fv mutants complexed with lysozyme.
Biochemistry, 35, 1996
1KJ7
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SUBSTRATE SHAPE DETERMINES SPECIFICITY OF RECOGNITION RECOGNITION FOR HIV-1 PROTEASE: ANALYSIS OF CRYSTAL STRUCTURES OF SIX SUBSTRATE COMPLEXES
Descriptor: ACETATE ION, POL POLYPROTEIN, gag polyprotein
Authors:Schiffer, C.A.
Deposit date:2001-12-04
Release date:2002-03-06
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Substrate shape determines specificity of recognition for HIV-1 protease: analysis of crystal structures of six substrate complexes.
Structure, 10, 2002
6UKZ
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STING C-terminal Domain Complexed with Non-cyclic Dinucleotide Compound 6
Descriptor: 4-[5-(2-{[2-(3-carboxypropanoyl)-4-fluoro-6-methoxy-1-benzothiophen-5-yl]oxy}ethoxy)-6-methoxy-1-benzothiophen-2-yl]-4-oxobutanoic acid, fusion protein of Ubiquitin-like protein SMT3 and Stimulator of interferon protein c-terminal domain
Authors:Lesburg, C.A.
Deposit date:2019-10-06
Release date:2020-08-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:An orally available non-nucleotide STING agonist with antitumor activity.
Science, 369, 2020

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數據於2025-12-03公開中

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