8RHR

E.coli Peptide Deformylase with bound inhibitor BB4

Summary for 8RHR

Entry DOI	10.2210/pdb8rhr/pdb
Descriptor	Peptide deformylase, ZINC ION, 2-(5-bromo-1H-indol-3-yl)-N-hydroxyacetamide, ... (6 entities in total)
Functional Keywords	peptide deformylase (ec 3.5.1.88), inhibitor, hydrolase
Biological source	Escherichia coli
Total number of polymer chains	1
Total formula weight	20135.51
Authors	Kirschner, H.,Stoll, R.,Hofmann, E. (deposition date: 2023-12-16, release date: 2024-04-17)
Primary citation	Kirschner, H.,Heister, N.,Zouatom, M.,Zhou, T.,Hofmann, E.,Scherkenbeck, J.,Stoll, R. Toward More Selective Antibiotic Inhibitors: A Structural View of the Complexed Binding Pocket of E. coli Peptide Deformylase. J.Med.Chem., 2024 Cited by PubMed: 38574272 DOI: 10.1021/acs.jmedchem.3c02382 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.42 Å)

Structure validation