8HX9
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![BU of 8hx9 by Molmil](/molmil-images/mine/8hx9) | Crystal structure of 4-amino-4-deoxychorismate synthase from Streptomyces venezuelae with chorismate | Descriptor: | (3R,4R)-3-[(1-carboxyethenyl)oxy]-4-hydroxycyclohexa-1,5-diene-1-carboxylic acid, 4-amino-4-deoxychorismate synthase, FORMIC ACID, ... | Authors: | Nakamichi, Y, Watanabe, M. | Deposit date: | 2023-01-04 | Release date: | 2023-10-18 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Structural basis for the allosteric pathway of 4-amino-4-deoxychorismate synthase. Acta Crystallogr D Struct Biol, 79, 2023
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8HX6
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![BU of 8hx6 by Molmil](/molmil-images/mine/8hx6) | |
8HX8
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![BU of 8hx8 by Molmil](/molmil-images/mine/8hx8) | |
8HX7
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![BU of 8hx7 by Molmil](/molmil-images/mine/8hx7) | |
4WIN
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![BU of 4win by Molmil](/molmil-images/mine/4win) | Crystal structure of the GATase domain from Plasmodium falciparum GMP synthetase | Descriptor: | GMP synthetase, NITRATE ION | Authors: | Ballut, L, Violot, S, Haser, R, Aghajari, N. | Deposit date: | 2014-09-26 | Release date: | 2015-12-02 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Active site coupling in Plasmodium falciparum GMP synthetase is triggered by domain rotation. Nat Commun, 6, 2015
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4WIM
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![BU of 4wim by Molmil](/molmil-images/mine/4wim) | |
4WXY
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![BU of 4wxy by Molmil](/molmil-images/mine/4wxy) | |
4WIO
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![BU of 4wio by Molmil](/molmil-images/mine/4wio) | Crystal structure of the C89A GMP synthetase inactive mutant from Plasmodium falciparum in complex with glutamine | Descriptor: | GLUTAMINE, GMP synthetase | Authors: | Ballut, L, Violot, S, Haser, R, Aghajari, N. | Deposit date: | 2014-09-26 | Release date: | 2015-12-02 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.15 Å) | Cite: | Active site coupling in Plasmodium falciparum GMP synthetase is triggered by domain rotation. Nat Commun, 6, 2015
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3R76
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![BU of 3r76 by Molmil](/molmil-images/mine/3r76) | Crystal structure of 2-amino-2-desoxyisochorismate synthase (ADIC) synthase PhzE from Burkholderia lata 383 in complex with benzoate, pyruvate and glutamine | Descriptor: | Anthranilate/para-aminobenzoate synthases component I, BENZOIC ACID, MAGNESIUM ION, ... | Authors: | Li, Q.A, Mavrodi, D.V, Thomashow, L.S, Roessle, M, Blankenfeldt, W. | Deposit date: | 2011-03-22 | Release date: | 2011-03-30 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Ligand Binding Induces an Ammonia Channel in 2-Amino-2-desoxyisochorismate (ADIC) Synthase PhzE. J.Biol.Chem., 286, 2011
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3R74
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![BU of 3r74 by Molmil](/molmil-images/mine/3r74) | Crystal structure of 2-amino-2-desoxyisochorismate synthase (ADIC) synthase PhzE from Burkholderia lata 383 | Descriptor: | Anthranilate/para-aminobenzoate synthases component I | Authors: | Li, Q.A, Mavrodi, D.V, Thomashow, L.S, Roessle, M, Blankenfeldt, W. | Deposit date: | 2011-03-22 | Release date: | 2011-03-30 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Ligand Binding Induces an Ammonia Channel in 2-Amino-2-desoxyisochorismate (ADIC) Synthase PhzE. J.Biol.Chem., 286, 2011
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3R75
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![BU of 3r75 by Molmil](/molmil-images/mine/3r75) | Crystal structure of 2-amino-2-desoxyisochorismate synthase (ADIC) synthase PhzE from Burkholderia lata 383 in complex with benzoate, pyruvate, glutamine and contaminating Zn2+ | Descriptor: | Anthranilate/para-aminobenzoate synthases component I, BENZOIC ACID, MAGNESIUM ION, ... | Authors: | Li, Q.A, Mavrodi, D.V, Thomashow, L.S, Roessle, M, Blankenfeldt, W. | Deposit date: | 2011-03-22 | Release date: | 2011-03-30 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Ligand Binding Induces an Ammonia Channel in 2-Amino-2-desoxyisochorismate (ADIC) Synthase PhzE. J.Biol.Chem., 286, 2011
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3TQI
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![BU of 3tqi by Molmil](/molmil-images/mine/3tqi) | Structure of the GMP synthase (guaA) from Coxiella burnetii | Descriptor: | GMP synthase [glutamine-hydrolyzing] | Authors: | Franklin, M.C, Cheung, J, Rudolph, M, Cassidy, M, Gary, E, Burshteyn, F, Love, J. | Deposit date: | 2011-09-09 | Release date: | 2011-09-28 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.84 Å) | Cite: | Structural genomics for drug design against the pathogen Coxiella burnetii. Proteins, 83, 2015
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4L7Q
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![BU of 4l7q by Molmil](/molmil-images/mine/4l7q) | Crystal structure of gamma glutamyl hydrolase (wild-type) from zebrafish | Descriptor: | GLYCEROL, Gamma-glutamyl hydrolase | Authors: | Chuankhayan, P, Kao, T.-T, Chen, C.-J, Fu, T.-F. | Deposit date: | 2013-06-14 | Release date: | 2014-05-14 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural insights into the hydrolysis and polymorphism of methotrexate polyglutamate by zebrafish gamma-glutamyl hydrolase J.Med.Chem., 56, 2013
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1S1M
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![BU of 1s1m by Molmil](/molmil-images/mine/1s1m) | Crystal Structure of E. Coli CTP Synthetase | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, CTP synthase, IODIDE ION, ... | Authors: | Endrizzi, J.A, Kim, H, Anderson, P.M, Baldwin, E.P. | Deposit date: | 2004-01-06 | Release date: | 2004-06-15 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal Structure of Escherichia coli Cytidine Triphosphate Synthetase, a Nucleotide-Regulated Glutamine Amidotransferase/ATP-Dependent Amidoligase Fusion Protein and Homologue of Anticancer and Antiparasitic Drug Targets Biochemistry, 43, 2004
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4L8F
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![BU of 4l8f by Molmil](/molmil-images/mine/4l8f) | Crystal structure of gamma-glutamyl hydrolase (C108A) complex with MTX | Descriptor: | Gamma-glutamyl hydrolase, METHOTREXATE | Authors: | Chuankhayan, P, Kao, T.-T, Chen, C.-J, Fu, T.-F. | Deposit date: | 2013-06-17 | Release date: | 2014-05-14 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Structural insights into the hydrolysis and polymorphism of methotrexate polyglutamate by zebrafish gamma-glutamyl hydrolase J.Med.Chem., 56, 2013
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4L8Y
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![BU of 4l8y by Molmil](/molmil-images/mine/4l8y) | |
1T36
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![BU of 1t36 by Molmil](/molmil-images/mine/1t36) | Crystal structure of E. coli carbamoyl phosphate synthetase small subunit mutant C248D complexed with uridine 5'-monophosphate | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, Carbamoyl-phosphate synthase large chain, ... | Authors: | Thoden, J.B, Huang, X, Raushel, F.M, Holden, H.M. | Deposit date: | 2004-04-24 | Release date: | 2004-09-21 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Long-range allosteric transitions in carbamoyl phosphate synthetase. Protein Sci., 13, 2004
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4L8W
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![BU of 4l8w by Molmil](/molmil-images/mine/4l8w) | Crystal structure of gamma glutamyl hydrolase (H218N) from zebrafish complex with MTX polyglutamate | Descriptor: | D-GLUTAMIC ACID, Gamma-glutamyl hydrolase, METHOTREXATE | Authors: | Chuankhayan, P, Kao, T.-T, Chen, C.-J, Fu, T.-F. | Deposit date: | 2013-06-18 | Release date: | 2014-05-14 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.39 Å) | Cite: | Structural insights into the hydrolysis and polymorphism of methotrexate polyglutamate by zebrafish gamma-glutamyl hydrolase J.Med.Chem., 56, 2013
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4L95
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![BU of 4l95 by Molmil](/molmil-images/mine/4l95) | Crystal structure of gamma glutamyl hydrolase (H218N) from zebrafish | Descriptor: | GLYCEROL, Gamma-glutamyl hydrolase | Authors: | Chuankhayan, P, Kao, T.-T, Chen, C.-J, Fu, T.-F. | Deposit date: | 2013-06-18 | Release date: | 2014-05-14 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.34 Å) | Cite: | Structural insights into the hydrolysis and polymorphism of methotrexate polyglutamate by zebrafish gamma-glutamyl hydrolase J.Med.Chem., 56, 2013
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1VCO
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![BU of 1vco by Molmil](/molmil-images/mine/1vco) | |
1VCM
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![BU of 1vcm by Molmil](/molmil-images/mine/1vcm) | |
1VCN
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![BU of 1vcn by Molmil](/molmil-images/mine/1vcn) | |
5U3C
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![BU of 5u3c by Molmil](/molmil-images/mine/5u3c) | |
5TW7
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![BU of 5tw7 by Molmil](/molmil-images/mine/5tw7) | |
5U6R
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![BU of 5u6r by Molmil](/molmil-images/mine/5u6r) | |