7ZF4
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![BU of 7zf4 by Molmil](/molmil-images/mine/7zf4) | SARS-CoV-2 Omicron RBD in complex with Omi-9 Fab and nanobody F2 | Descriptor: | Nanobody F2, Omi-9 heavy chain, Omi-9 light chain, ... | Authors: | Zhou, D, Huo, J, Ren, J, Stuart, D.I. | Deposit date: | 2022-04-01 | Release date: | 2022-06-08 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (4.18 Å) | Cite: | Potent cross-reactive antibodies following Omicron breakthrough in vaccinees. Cell, 185, 2022
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7ZF3
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![BU of 7zf3 by Molmil](/molmil-images/mine/7zf3) | SARS-CoV-2 Omicron RBD in complex with Omi-3 and EY6A Fabs | Descriptor: | EY6A heavy chain, EY6A light chain, GLYCEROL, ... | Authors: | Zhou, D, Huo, J, Ren, J, Stuart, D.I. | Deposit date: | 2022-04-01 | Release date: | 2022-06-01 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (3.15 Å) | Cite: | Potent cross-reactive antibodies following Omicron breakthrough in vaccinees. Cell, 185, 2022
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7ZF2
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![BU of 7zf2 by Molmil](/molmil-images/mine/7zf2) | Protomeric substructure from an octameric assembly of M. tuberculosis RNA polymerase in complex with sigma-b initiation factor | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | Authors: | Trapani, S, Bron, P, Lai Kee Him, J, Brodolin, K, Morichaud, Z, Vishwakarma, R. | Deposit date: | 2022-03-31 | Release date: | 2023-02-08 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.86 Å) | Cite: | Structural basis of the mycobacterial stress-response RNA polymerase auto-inhibition via oligomerization. Nat Commun, 14, 2023
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7ZEN
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![BU of 7zen by Molmil](/molmil-images/mine/7zen) | BRD4 in complex with FragLite23 | Descriptor: | 2-(4-bromo-1H-pyrazol-1-yl)ethan-1-ol, GLYCEROL, Isoform C of Bromodomain-containing protein 4 | Authors: | Turberville, S, Martin, M.P, Hope, I, Noble, M.E.M. | Deposit date: | 2022-03-31 | Release date: | 2022-11-23 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.14 Å) | Cite: | Mapping Ligand Interactions of Bromodomains BRD4 and ATAD2 with FragLites and PepLites─Halogenated Probes of Druglike and Peptide-like Molecular Interactions. J.Med.Chem., 65, 2022
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7ZEI
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![BU of 7zei by Molmil](/molmil-images/mine/7zei) | Thermostable GH159 glycoside hydrolase from Caldicellulosiruptor at 1.7 A | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, ... | Authors: | Baudrexl, M, Fida, T, Berk, B, Schwarz, W, Zverlov, V.V, Groll, M, Liebl, W. | Deposit date: | 2022-03-31 | Release date: | 2022-08-03 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Biochemical and Structural Characterization of Thermostable GH159 Glycoside Hydrolases Exhibiting alpha-L-Arabinofuranosidase Activity. Front Mol Biosci, 9, 2022
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7ZEH
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![BU of 7zeh by Molmil](/molmil-images/mine/7zeh) | Human cytosolic 5' nucleotidase IIIB in complex with 3,4-diF-Bn7Guanine | Descriptor: | 1,2-ETHANEDIOL, 7-methylguanosine phosphate-specific 5'-nucleotidase, D-ribulose, ... | Authors: | Kubacka, D, Kozarski, M, Baranowski, M.R, Wojcik, R, Jemielity, J, Kowalska, J, Basquin, J. | Deposit date: | 2022-03-31 | Release date: | 2022-05-25 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Substrate-Based Design of Cytosolic Nucleotidase IIIB Inhibitors and Structural Insights into Inhibition Mechanism. Pharmaceuticals, 15, 2022
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7ZEG
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![BU of 7zeg by Molmil](/molmil-images/mine/7zeg) | Human cytosolic 5' nucleotidase IIIB in complex with 3,4-diF-Bn7GMP | Descriptor: | 1,2-ETHANEDIOL, 7-methylguanosine phosphate-specific 5'-nucleotidase, MAGNESIUM ION, ... | Authors: | Kubacka, D, Kozarski, M, Baranowski, M.R, Wojcik, R, Jemielity, J, Kowalska, J, Basquin, J. | Deposit date: | 2022-03-31 | Release date: | 2022-04-13 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.56 Å) | Cite: | Substrate-Based Design of Cytosolic Nucleotidase IIIB Inhibitors and Structural Insights into Inhibition Mechanism. Pharmaceuticals, 15, 2022
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7ZEF
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![BU of 7zef by Molmil](/molmil-images/mine/7zef) | BRD4 in complex with FragLite22 | Descriptor: | (4-bromo-2-methoxyphenyl)methanol, Bromodomain-containing protein 4, GLYCEROL | Authors: | Turberville, S, Martin, M.P, Hope, I, Noble, M.E.M. | Deposit date: | 2022-03-31 | Release date: | 2022-11-23 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.12 Å) | Cite: | Mapping Ligand Interactions of Bromodomains BRD4 and ATAD2 with FragLites and PepLites─Halogenated Probes of Druglike and Peptide-like Molecular Interactions. J.Med.Chem., 65, 2022
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7ZEE
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![BU of 7zee by Molmil](/molmil-images/mine/7zee) | Human cytosolic 5' nucleotidase IIIB | Descriptor: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 7-methylguanosine phosphate-specific 5'-nucleotidase, ... | Authors: | Kubacka, D, Kozarski, M, Baranowski, M.R, Wojcik, R, Jemielity, J, Kowalska, J, Basquin, J. | Deposit date: | 2022-03-31 | Release date: | 2022-04-13 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.36 Å) | Cite: | Substrate-Based Design of Cytosolic Nucleotidase IIIB Inhibitors and Structural Insights into Inhibition Mechanism. Pharmaceuticals, 15, 2022
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7ZEB
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![BU of 7zeb by Molmil](/molmil-images/mine/7zeb) | Complex I from Ovis aries at pH9, Closed state | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ADENOSINE MONOPHOSPHATE, ... | Authors: | Sazanov, L, Petrova, O. | Deposit date: | 2022-03-30 | Release date: | 2022-09-21 | Last modified: | 2022-10-05 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | A universal coupling mechanism of respiratory complex I. Nature, 609, 2022
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7ZEA
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![BU of 7zea by Molmil](/molmil-images/mine/7zea) | |
7ZE7
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![BU of 7ze7 by Molmil](/molmil-images/mine/7ze7) | BRD4 in complex with FragLite21 | Descriptor: | 5-bromo-2-hydroxybenzonitrile, Bromodomain-containing protein 4, GLYCEROL | Authors: | Turberville, S, Martin, M.P, Hope, I, Noble, M.E.M. | Deposit date: | 2022-03-30 | Release date: | 2022-12-07 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.23 Å) | Cite: | Mapping Ligand Interactions of Bromodomains BRD4 and ATAD2 with FragLites and PepLites─Halogenated Probes of Druglike and Peptide-like Molecular Interactions. J.Med.Chem., 65, 2022
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7ZE6
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![BU of 7ze6 by Molmil](/molmil-images/mine/7ze6) | BRD4 in complex with FragLite10 | Descriptor: | 6-bromo-1,3-dihydro-2H-indol-2-one, Bromodomain-containing protein 4, GLYCEROL | Authors: | Turberville, S, Martin, M.P, Hope, I, Noble, M.E.M. | Deposit date: | 2022-03-30 | Release date: | 2022-11-23 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.04 Å) | Cite: | Mapping Ligand Interactions of Bromodomains BRD4 and ATAD2 with FragLites and PepLites─Halogenated Probes of Druglike and Peptide-like Molecular Interactions. J.Med.Chem., 65, 2022
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7ZDQ
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![BU of 7zdq by Molmil](/molmil-images/mine/7zdq) | Cryo-EM structure of Human ACE2 bound to a high-affinity SARS CoV-2 mutant | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, Spike protein S1 | Authors: | Bate, N, Savva, C.G, Moody, P.C.E, Brown, E.A, Schwabe, W.R, Brindle, N.P.J, Ball, J.K, Sale, J.E. | Deposit date: | 2022-03-29 | Release date: | 2022-05-18 | Last modified: | 2022-08-10 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | In vitro evolution predicts emerging SARS-CoV-2 mutations with high affinity for ACE2 and cross-species binding. Plos Pathog., 18, 2022
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7ZDP
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![BU of 7zdp by Molmil](/molmil-images/mine/7zdp) | Complex I from Ovis aries at pH9, Open state | Descriptor: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ADENOSINE MONOPHOSPHATE, Acyl carrier protein, ... | Authors: | Sazanov, L, Petrova, O. | Deposit date: | 2022-03-29 | Release date: | 2022-09-21 | Last modified: | 2022-10-05 | Method: | ELECTRON MICROSCOPY (3.88 Å) | Cite: | A universal coupling mechanism of respiratory complex I. Nature, 609, 2022
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7ZDM
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![BU of 7zdm by Molmil](/molmil-images/mine/7zdm) | Complex I from Ovis aries at pH5.5, Closed state | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ... | Authors: | Sazanov, L, Petrova, O. | Deposit date: | 2022-03-29 | Release date: | 2022-09-21 | Last modified: | 2022-10-05 | Method: | ELECTRON MICROSCOPY (3.44 Å) | Cite: | A universal coupling mechanism of respiratory complex I. Nature, 609, 2022
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7ZDJ
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![BU of 7zdj by Molmil](/molmil-images/mine/7zdj) | Complex I from Ovis aries at pH5.5, Open state | Descriptor: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Acyl carrier protein, Complex I subunit B13, ... | Authors: | Petrova, O, Sazanov, L. | Deposit date: | 2022-03-29 | Release date: | 2022-09-21 | Last modified: | 2022-10-05 | Method: | ELECTRON MICROSCOPY (3.25 Å) | Cite: | A universal coupling mechanism of respiratory complex I. Nature, 609, 2022
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7ZDH
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![BU of 7zdh by Molmil](/molmil-images/mine/7zdh) | Complex I from Ovis aries at pH7.4, Closed state | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ... | Authors: | Sazanov, L, Petrova, O. | Deposit date: | 2022-03-29 | Release date: | 2022-09-21 | Last modified: | 2022-10-05 | Method: | ELECTRON MICROSCOPY (3.46 Å) | Cite: | A universal coupling mechanism of respiratory complex I. Nature, 609, 2022
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7ZDF
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![BU of 7zdf by Molmil](/molmil-images/mine/7zdf) | |
7ZDD
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![BU of 7zdd by Molmil](/molmil-images/mine/7zdd) | Crystal structure of TRIM33 PHD-Bromodomain isoform B in complex with H3K10ac histone peptide. | Descriptor: | 1,2-ETHANEDIOL, E3 ubiquitin-protein ligase TRIM33, Histone H3.X, ... | Authors: | Caria, S, Duclos, S, Crespillo, S, Errey, J, Barker, J.J. | Deposit date: | 2022-03-29 | Release date: | 2022-06-29 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.625 Å) | Cite: | Identification of Histone Peptide Binding Specificity and Small-Molecule Ligands for the TRIM33 alpha and TRIM33 beta Bromodomains. Acs Chem.Biol., 17, 2022
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7ZD9
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![BU of 7zd9 by Molmil](/molmil-images/mine/7zd9) | Crystal structure of the E352T mutant of S-adenosyl-L-homocysteine hydrolase from Synechocystis sp. PCC 6803 cocrystallized with adenosine in the presence of Rb+ cations | Descriptor: | ADENOSINE, Adenosylhomocysteinase, CHLORIDE ION, ... | Authors: | Malecki, P.H, Imiolczyk, B, Wozniak, K, Brzezinski, K. | Deposit date: | 2022-03-29 | Release date: | 2022-07-13 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | Biochemical and structural insights into an unusual, alkali-metal-independent S-adenosyl-L-homocysteine hydrolase from Synechocystis sp. PCC 6803. Acta Crystallogr D Struct Biol, 78, 2022
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7ZD8
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![BU of 7zd8 by Molmil](/molmil-images/mine/7zd8) | Crystal structure of the R24E mutant of S-adenosyl-L-homocysteine hydrolase from Synechocystis sp. PCC 6803 cocrystallized with adenosine in the presence of Rb+ cations | Descriptor: | ADENOSINE, Adenosylhomocysteinase, CHLORIDE ION, ... | Authors: | Malecki, P.H, Imiolczyk, B, Wozniak, K, Brzezinski, K. | Deposit date: | 2022-03-29 | Release date: | 2022-07-13 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Biochemical and structural insights into an unusual, alkali-metal-independent S-adenosyl-L-homocysteine hydrolase from Synechocystis sp. PCC 6803. Acta Crystallogr D Struct Biol, 78, 2022
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7ZD7
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![BU of 7zd7 by Molmil](/molmil-images/mine/7zd7) | Crystal structure of the R24E/E352T double mutant of S-adenosyl-L-homocysteine hydrolase from Synechocystis sp. PCC 6803 cocrystallized with adenosine in the presence of Rb+ cations | Descriptor: | ADENOSINE, Adenosylhomocysteinase, CHLORIDE ION, ... | Authors: | Malecki, P.H, Imiolczyk, B, Wozniak, K, Brzezinski, K. | Deposit date: | 2022-03-29 | Release date: | 2022-07-13 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Biochemical and structural insights into an unusual, alkali-metal-independent S-adenosyl-L-homocysteine hydrolase from Synechocystis sp. PCC 6803. Acta Crystallogr D Struct Biol, 78, 2022
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7ZD6
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![BU of 7zd6 by Molmil](/molmil-images/mine/7zd6) | Complex I from Ovis aries, at pH7.4, Open state | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ... | Authors: | Sazanov, L, Petrova, O. | Deposit date: | 2022-03-29 | Release date: | 2022-09-21 | Last modified: | 2022-10-05 | Method: | ELECTRON MICROSCOPY (3.16 Å) | Cite: | A universal coupling mechanism of respiratory complex I. Nature, 609, 2022
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7ZD3
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![BU of 7zd3 by Molmil](/molmil-images/mine/7zd3) | Crystal structure of Pseudomonas aeruginosa S-adenosyl-L-homocysteine hydrolase inhibited by Zn2+ ions | Descriptor: | 1,3-PROPANDIOL, 1,4-BUTANEDIOL, ADENOSINE, ... | Authors: | Malecki, P.H, Gawel, M, Brzezinski, K. | Deposit date: | 2022-03-29 | Release date: | 2023-04-19 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of Pseudomonas aeruginosa S-adenosyl-L-homocysteine hydrolase inhibited by Zn2+ ions To Be Published
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