7ZEE

Human cytosolic 5' nucleotidase IIIB

Summary for 7ZEE

Entry DOI	10.2210/pdb7zee/pdb
Descriptor	7-methylguanosine phosphate-specific 5'-nucleotidase, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, MAGNESIUM ION, ... (5 entities in total)
Functional Keywords	cytosolic 5' nucleotidase, n7 methylguanosine monophosphate dephosphorylation, mrna cap degradation, nucleotide level regulation, hydrolase
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	35702.11
Authors	Kubacka, D.,Kozarski, M.,Baranowski, M.R.,Wojcik, R.,Jemielity, J.,Kowalska, J.,Basquin, J. (deposition date: 2022-03-31, release date: 2022-04-13, Last modification date: 2024-01-31)
Primary citation	Kubacka, D.,Kozarski, M.,Baranowski, M.R.,Wojcik, R.,Panecka-Hofman, J.,Strzelecka, D.,Basquin, J.,Jemielity, J.,Kowalska, J. Substrate-Based Design of Cytosolic Nucleotidase IIIB Inhibitors and Structural Insights into Inhibition Mechanism. Pharmaceuticals, 15:-, 2022 Cited by PubMed: 35631380 DOI: 10.3390/ph15050554 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.36 Å)

Structure validation