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7OHP
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BU of 7ohp by Molmil
Nog1-TAP associated immature ribosomal particles from S. cerevisiae after rpL25 expression shut down, population A
Descriptor: 25S rRNA, 5.8S rRNA, 60S ribosomal protein L13-A, ...
Authors:Milkereit, P, Poell, G.
Deposit date:2021-05-11
Release date:2021-11-03
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Analysis of subunit folding contribution of three yeast large ribosomal subunit proteins required for stabilisation and processing of intermediate nuclear rRNA precursors.
Plos One, 16, 2021
7OHX
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BU of 7ohx by Molmil
Nog1-TAP associated immature ribosomal particles from S. cerevisiae after rpL34 expression shut down, population A
Descriptor: 25S rRNA, 5.8S rRNA, 60S ribosomal protein L13-A, ...
Authors:Milkereit, P, Poell, G.
Deposit date:2021-05-11
Release date:2021-11-03
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Analysis of subunit folding contribution of three yeast large ribosomal subunit proteins required for stabilisation and processing of intermediate nuclear rRNA precursors.
Plos One, 16, 2021
7OHT
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BU of 7oht by Molmil
Nog1-TAP associated immature ribosomal particles from S. cerevisiae after rpL2 expression shut down, population A
Descriptor: 25S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Milkereit, P, Poell, G.
Deposit date:2021-05-11
Release date:2021-11-03
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (4.7 Å)
Cite:Analysis of subunit folding contribution of three yeast large ribosomal subunit proteins required for stabilisation and processing of intermediate nuclear rRNA precursors.
Plos One, 16, 2021
8DCS
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BU of 8dcs by Molmil
Cryo-EM structure of cyanopindolol-bound beta1-adrenergic receptor in complex with heterotrimeric Gs-protein
Descriptor: 4-{[(2S)-3-(tert-butylamino)-2-hydroxypropyl]oxy}-3H-indole-2-carbonitrile, Endolysin,Endolysin,Beta-1 adrenergic receptor chimera, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Su, M, Paknejad, N, Hite, R.K, Huang, X.Y.
Deposit date:2022-06-17
Release date:2022-07-27
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Structures of beta 1 -adrenergic receptor in complex with Gs and ligands of different efficacies.
Nat Commun, 13, 2022
8DCR
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BU of 8dcr by Molmil
Cryo-EM structure of dobutamine-bound beta1-adrenergic receptor in complex with heterotrimeric Gs-protein
Descriptor: DOBUTAMINE, Endolysin,Endolysin,Beta-1 adrenergic receptor chimera, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Su, M, Paknejad, N, Hite, R.K, Huang, X.Y.
Deposit date:2022-06-17
Release date:2022-07-27
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Structures of beta 1 -adrenergic receptor in complex with Gs and ligands of different efficacies.
Nat Commun, 13, 2022
6G6N
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BU of 6g6n by Molmil
Crystal structure of the computationally designed Tako8 protein in C2
Descriptor: Tako8
Authors:Noguchi, H, Addy, C, Simoncini, D, Van Meervelt, L, Schiex, T, Zhang, K.Y.J, Tame, J.R.H, Voet, A.R.D.
Deposit date:2018-04-01
Release date:2018-11-28
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.001 Å)
Cite:Computational design of symmetrical eight-bladed beta-propeller proteins.
IUCrJ, 6, 2019
5HQG
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BU of 5hqg by Molmil
WD40 domain of Human E3 Ubiquitin Ligase COP1 (RFWD2)
Descriptor: E3 ubiquitin-protein ligase RFWD2
Authors:Uljon, S, Blacklow, S.C.
Deposit date:2016-01-21
Release date:2016-04-20
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Basis for Substrate Selectivity of the E3 Ligase COP1.
Structure, 24, 2016
5ZCU
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BU of 5zcu by Molmil
Crystal structure of RCAR3:PP2C wild-type with pyrabactin
Descriptor: 4-bromo-N-(pyridin-2-ylmethyl)naphthalene-1-sulfonamide, ABA receptor RCAR3, MAGNESIUM ION, ...
Authors:Han, S, Lee, Y, Lee, S.
Deposit date:2018-02-20
Release date:2019-03-06
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.413 Å)
Cite:Structural determinants for pyrabactin recognition in ABA receptors in Oryza sativa.
Plant Mol.Biol., 100, 2019
5ZEP
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BU of 5zep by Molmil
M. smegmatis hibernating state 70S ribosome structure
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Mishra, S, Ahmed, T, Tyagi, A, Shi, J, Bhushan, S.
Deposit date:2018-02-27
Release date:2018-09-26
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structures of Mycobacterium smegmatis 70S ribosomes in complex with HPF, tmRNA, and P-tRNA.
Sci Rep, 8, 2018
5HYN
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BU of 5hyn by Molmil
Structure of Human Polycomb Repressive Complex 2 (PRC2) with oncogenic histone H3K27M peptide
Descriptor: H3K27M, Histone-lysine N-methyltransferase EZH2, JARID2 K116me3, ...
Authors:Zhang, Y, Justin, N, Wilson, J.R, Gamblin, S.J.
Deposit date:2016-02-01
Release date:2016-05-11
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Structural basis of oncogenic histone H3K27M inhibition of human polycomb repressive complex 2.
Nat Commun, 7, 2016
6E1Z
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BU of 6e1z by Molmil
Displacement of WDR5 from chromatin by a pharmacological WIN site inhibitor with picomolar affinity
Descriptor: 5-[(1H-imidazol-1-yl)methyl]furan-2-carboxylic acid, WD repeat-containing protein 5
Authors:Phan, J, Fesik, S.W.
Deposit date:2018-07-10
Release date:2019-03-13
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Displacement of WDR5 from Chromatin by a WIN Site Inhibitor with Picomolar Affinity.
Cell Rep, 26, 2019
6DZI
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BU of 6dzi by Molmil
Cryo-EM Structure of Mycobacterium smegmatis 70S C(minus) ribosome 70S-MPY complex
Descriptor: 16S rRNA, 23 S rRNA (3119-MER), 30S ribosomal protein S10, ...
Authors:Sharma, M.R, Li, Y, Korripella, R, Yang, Y, Kaushal, P.S, Lin, Q, Wade, J.T, Gray, A.G, Derbyshire, K.M, Agrawal, R.K, Ojha, A.
Deposit date:2018-07-05
Release date:2018-09-26
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.46 Å)
Cite:Zinc depletion induces ribosome hibernation in mycobacteria.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
7O5B
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BU of 7o5b by Molmil
Cryo-EM structure of a Bacillus subtilis MifM-stalled ribosome-nascent chain complex with (p)ppGpp-SRP bound
Descriptor: 16S rRNA (1533-MER), 23S rRNA (2887-MER), 30S ribosomal protein S10, ...
Authors:Kratzat, H, Czech, L, Berninghausen, O, Bange, G, Beckmann, R.
Deposit date:2021-04-08
Release date:2022-02-02
Last modified:2022-03-09
Method:ELECTRON MICROSCOPY (3.33 Å)
Cite:Inhibition of SRP-dependent protein secretion by the bacterial alarmone (p)ppGpp.
Nat Commun, 13, 2022
6E23
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BU of 6e23 by Molmil
Displacement of WDR5 from chromatin by a pharmacological WIN site inhibitor with picomolar affinity
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, N-[(3,4-dichlorophenyl)methyl]-3-(6-fluoro-2-methylpyridin-3-yl)-5-{[(2E)-2-imino-3-methyl-2,3-dihydro-1H-imidazol-1-yl]methyl}benzamide, WD repeat-containing protein 5
Authors:Phan, J, Fesik, S.W.
Deposit date:2018-07-10
Release date:2019-03-13
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Displacement of WDR5 from Chromatin by a WIN Site Inhibitor with Picomolar Affinity.
Cell Rep, 26, 2019
6E22
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BU of 6e22 by Molmil
Displacement of WDR5 from chromatin by a pharmacological WIN site inhibitor with picomolar affinity
Descriptor: 3-{[(4,5-dihydro-1H-imidazol-2-yl)amino]methyl}-N-[(3,5-dimethoxyphenyl)methyl]-4-fluorobenzamide, SULFATE ION, WD repeat-containing protein 5
Authors:Phan, J, Fesik, S.W.
Deposit date:2018-07-10
Release date:2019-03-13
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Displacement of WDR5 from Chromatin by a WIN Site Inhibitor with Picomolar Affinity.
Cell Rep, 26, 2019
6GSN
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BU of 6gsn by Molmil
Structure of a partial yeast 48S preinitiation complex in closed conformation
Descriptor: 18S rRNA (1798-MER), 40S ribosomal protein S0, 40S ribosomal protein S1, ...
Authors:Llacer, J.L, Hussain, T, Ramakrishnan, V.
Deposit date:2018-06-14
Release date:2019-06-26
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (5.75 Å)
Cite:Large-scale movement of eIF3 domains during translation initiation modulate start codon selection.
Nucleic Acids Res., 2021
5ZEB
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BU of 5zeb by Molmil
M. Smegmatis P/P state 70S ribosome structure
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Mishra, S, Ahmed, T, Tyagi, A, Shi, J, Bhushan, S.
Deposit date:2018-02-27
Release date:2018-09-26
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structures of Mycobacterium smegmatis 70S ribosomes in complex with HPF, tmRNA, and P-tRNA.
Sci Rep, 8, 2018
5Z4T
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BU of 5z4t by Molmil
Complex structure - AxMan113A-M3
Descriptor: beta-1,4-mannanas, beta-D-mannopyranose-(1-4)-beta-D-mannopyranose
Authors:Jiang, Z.Q, You, X, Yang, S.Q, Huang, P, Ma, J.W.
Deposit date:2018-01-13
Release date:2018-06-20
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Structural insights into the catalytic mechanism of a novel glycoside hydrolase family 113 beta-1,4-mannanase fromAmphibacillus xylanus
J. Biol. Chem., 293, 2018
5FK7
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BU of 5fk7 by Molmil
Structure of D80A-fructofuranosidase from Xanthophyllomyces dendrorhous complexed with neokestose
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BETA-FRUCTOFURANOSIDASE, ...
Authors:Ramirez-Escudero, M, Sanz-Aparicio, J.
Deposit date:2015-10-15
Release date:2016-02-10
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural Analysis of Beta-Fructofuranosidase from Xanthophyllomyces Dendrorhous Reveals Unique Features and the Crucial Role of N-Glycosylation in Oligomerization and Activity
J.Biol.Chem., 291, 2016
5FLX
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BU of 5flx by Molmil
Mammalian 40S HCV-IRES complex
Descriptor: 18S RRNA, 40S RIBOSOMAL PROTEIN S10, 40S RIBOSOMAL PROTEIN S11, ...
Authors:Yamamoto, H, Collier, M, Loerke, J, Ismer, J, Schmidt, A, Hilal, T, Sprink, T, Yamamoto, K, Mielke, T, Burger, J, Shaikh, T.R, Dabrowski, M, Hildebrand, P.W, Scheerer, P, Spahn, C.M.T.
Deposit date:2015-10-28
Release date:2015-12-23
Last modified:2017-08-30
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Molecular Architecture of the Ribosome-Bound Hepatitis C Virus Internal Ribosomal Entry Site RNA.
Embo J., 34, 2015
6GQ1
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BU of 6gq1 by Molmil
Cryo-EM reconstruction of yeast 80S ribosome in complex with mRNA, tRNA and eEF2 (GMPPCP/sordarin)
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
Authors:Pellegrino, S, Demeshkina, N, Mancera-Martinez, E, Melnikov, S, Simonetti, A, Myasnikov, A, Yusupov, M, Yusupova, G, Hashem, Y.
Deposit date:2018-06-07
Release date:2018-07-11
Last modified:2018-08-08
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Structural Insights into the Role of Diphthamide on Elongation Factor 2 in mRNA Reading-Frame Maintenance.
J. Mol. Biol., 430, 2018
6FZC
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BU of 6fzc by Molmil
Crystal Structure of lipase from Geobacillus stearothermophilus T6 variant L184F/L360F
Descriptor: CALCIUM ION, Lipase, ZINC ION
Authors:Gihaz, S, Kanteev, M, Pazy, Y, Fishman, A.
Deposit date:2018-03-14
Release date:2018-10-17
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Filling the Void: Introducing Aromatic Interactions into Solvent Tunnels To Enhance Lipase Stability in Methanol.
Appl.Environ.Microbiol., 84, 2018
5F93
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BU of 5f93 by Molmil
Blood group antigen binding adhesin BabA of Helicobacter pylori strain A730 in complex with blood group H Lewis b hexasaccharide
Descriptor: Adhesin binding fucosylated histo-blood group antigen,Adhesin,Adhesin binding fucosylated histo-blood group antigen, Nanobody Nb-ER19, alpha-L-fucopyranose-(1-2)-beta-D-galactopyranose-(1-3)-[alpha-L-fucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose
Authors:Moonens, K, Gideonsson, P, Subedi, S, Romao, E, Oscarson, S, Muyldermans, S, Boren, T, Remaut, H.
Deposit date:2015-12-09
Release date:2016-01-20
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.99 Å)
Cite:Structural Insights into Polymorphic ABO Glycan Binding by Helicobacter pylori.
Cell Host Microbe, 19, 2016
5F8R
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BU of 5f8r by Molmil
Blood group antigen binding adhesin BabA of Helicobacter pylori strain S831 in complex with blood group H Lewis b hexasaccharide
Descriptor: Adhesin binding fucosylated histo-blood group antigen,Adhesin,Adhesin binding fucosylated histo-blood group antigen, Nanobody Nb-ER19, alpha-L-fucopyranose-(1-2)-beta-D-galactopyranose-(1-3)-[alpha-L-fucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose
Authors:Moonens, K, Gideonsson, P, Subedi, S, Romao, E, Oscarson, S, Muyldermans, S, Boren, T, Remaut, H.
Deposit date:2015-12-09
Release date:2016-01-20
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.44 Å)
Cite:Structural Insights into Polymorphic ABO Glycan Binding by Helicobacter pylori.
Cell Host Microbe, 19, 2016
5FA5
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BU of 5fa5 by Molmil
Crystal Structure of PRMT5:MEP50 in complex with MTA and H4 peptide
Descriptor: 5'-DEOXY-5'-METHYLTHIOADENOSINE, Histone H4, Methylosome protein 50, ...
Authors:Sprague, E.R, McNamara, J.T.
Deposit date:2015-12-10
Release date:2016-02-24
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Disordered methionine metabolism in MTAP/CDKN2A-deleted cancers leads to dependence on PRMT5.
Science, 351, 2016

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數據於2024-10-09公開中

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